Antibiotic
ofloxacin
[ oh-flok-suh-sin ]
Brand Names:
Floxin; Ocuflox
Effect:
Decreased DNA Integrity; Decreased DNA Replication; Decreased Transcription to RNA
May Treat:
Bronchitis;
Chlamydia Infections;
Conjunctivitis, Bacterial;
Corneal Ulcer;
Cystitis;
Epididymitis;
Escherichia coli Infections;
Gonorrhea;
Haemophilus Infections;
Helicobacter Infections;
Klebsiella Infections;
Otitis Externa;
Otitis Media, Suppurative;
Prostatitis;
Proteus Infections;
Salmonella Infections;
Skin Diseases, Bacterial;
Soft Tissue Infections;
Staphylococcal Infections;
Tuberculosis, Pulmonary;
Urinary Tract Infections
More Information:
Definitions related to ofloxacin:
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A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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An antibiotic drug used to treat infection. It belongs to the family of drugs called quinolone antibiotics.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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