Disease or Syndrome
osteoarthritis
os·te·o·ar·thri·tis [ os-tee-oh-ahr-thrahy-tis ]
Subclass of:
Rheumatism;
Arthritis
Etymology:
Greek osteon = bone + arthron = joint + -itis = inflammation
Also called:
Degenerative joint disease; OA; Osteoarthrosis; Hypertrophic Osteoarthritis
Definitions related to degenerative polyarthritis:
-
(degenerative joint disease) A disease process characterized by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. (INHAND)CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
-
(osteoarthritis) A joint disease in which the cartilage that lines the joints slowly deteriorates. Also called degenerative joint disease.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
-
(osteoarthritis) A noninflammatory degenerative joint disease occurring chiefly in older persons, characterised by degeneration of the articular cartilage, hypertrophy of bone at the margins and changes in the synovial membrane. It is accompanied by pain and stiffness, particularly after prolonged activity.NCI ThesaurusU.S. National Cancer Institute, 2021
-
(osteoarthritis) A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
-
(osteoarthritis) Degeneration (wear and tear) of articular cartilage, i.e., of the joint surface. Joint degeneration may be accompanied by osteophytes (bone overgrowth), narrowing of the joint space, regions of sclerosis at the joint surface, or joint deformity.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
-
(osteoarthritis) Noninflammatory degenerative joint disease occurring chiefly in older persons, characterized by degeneration of the articular cartilage, hypertrophy of bone at the margins, and changes in the synovial membrane, accompanied by pain and stiffness.CRISP ThesaurusNational Institutes of Health, 2006
-
(osteoarthritis) Osteoarthritis is the most common form of arthritis. It causes pain, swelling, and reduced motion in your joints. It can occur in any joint, but usually it affects your hands, knees, hips or spine. Osteoarthritis breaks down the cartilage in your joints. Cartilage is the slippery tissue that covers the ends of bones in a joint. Healthy cartilage absorbs the shock of movement. When you lose cartilage, your bones rub together. Over time, this rubbing can permanently damage the joint. Risk factors for osteoarthritis include Being overweight; Getting older; Injuring a joint . There is no specific test for osteoarthritis. Most doctors use several methods, including medical history, a physical exam, x-rays, or lab tests. Treatments include exercise, medicines, and sometimes surgery. NIH: National Institute of Arthritis and Musculoskeletal and Skin DiseasesMedlinePlusU.S. National Library of Medicine, 2021
-
Osteoarthritis is a chronic arthropathy characterized by disruption and potential loss of joint cartilage along with other joint changes, including bone hypertrophy (osteophyte formation). Symptoms include gradually developing pain aggravated or triggered by activity, stiffness lasting < 30 minutes on awakening and after inactivity, and...Merck & Co., Inc., 2020
-
Osteoarthritis is the most common type of joint disease, affecting more than 20 million individuals in the United States alone (see Epidemiology). It represents a heterogeneous group of conditions resulting in common histopathologic and radiologic changes.WebMD, 2019
-
Osteoarthritis is the most common form of arthritis, affecting millions of people worldwide. It occurs when the protective cartilage that cushions the ends of your bones wears down over time.Mayo Foundation for Medical Education and Research
-
Osteoarthritis (OA) is the result of mechanical and biologic events that destabilize the normal process of degradation and synthesis of articular cartilage chondrocytes, extracellular matrix, and subchondral bone. It involves the entire joint, including the articular cartilage, subchondral bone, pericapsular muscles, capsule, and...Athenahealth, Inc., 2019
-
Osteoarthritis, disorder of the joints characterized by progressive deterioration of the articular cartilage or of the entire joint, including the articular cartilage, the synovium (joint lining), the ligaments, and the subchondral bone (bone beneath the cartilage). Osteoarthritis is the most...Encyclopedia Britannica, Inc., 2020
Return to OpenMD Medical Dictionary
> O
This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.