Disease or Syndrome
osteoporosis
os·te·o·po·ro·sis [ os-tee-oh-puh-roh-sis ]
Subclass of:
Metabolic Bone Disorder
Etymology:
Greek osteon = bone + poros = passage or pore + -osis = condition
Definitions related to osteoporosis:
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A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).NCI ThesaurusU.S. National Cancer Institute, 2021
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A condition that is marked by a decrease in bone mass and density, causing bones to become fragile.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Loss of bone mass and strength due to nutritional, metabolic, or other factors, usually resulting in deformity or fracture; a major public health problem of the elderly, especially women.CRISP ThesaurusNational Institutes of Health, 2006
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Osteoporosis is a disease that thins and weakens the bones. Your bones become fragile and fracture (break) easily, especially the bones in the hip, spine, and wrist. In the United States, millions of people either already have osteoporosis or are at high risk due to low bone mass. Anyone can develop osteoporosis, but it is more common in older women. Risk factors include Getting older; Being small and thin; Having a family history of osteoporosis; Taking certain medicines; Being a white or Asian woman; Having low bone density. Osteoporosis is a silent disease. You might not know you have it until you break a bone. A bone mineral density test is the best way to check your bone health. To keep bones strong, eat a diet rich in calcium and vitamin D, exercise, and do not smoke. If needed, medicines can also help. It is also important to try to avoid falling down. Falls are the number one cause of fractures in older adults. NIH: National Institute of Arthritis and Musculoskeletal and Skin DiseasesMedlinePlusU.S. National Library of Medicine, 2021
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Osteoporosis is a systemic skeletal disease characterized by low bone density and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility. According to the WHO criteria, osteoporosis is defined as a BMD that lies 2.5 standard deviations or more below the average value for young healthy adults (a T-score below -2.5 SD).Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Reduced bone mineral density due to decreased number and thickness of bone trabeculae and decreased cortical thickness, associated with increased risk of skeletal fractures. A clinical diagnosis of osteoporosis in childhood requires either a finding of one or more otherwise unexplained vertebral compression fractures, or the presence of bone mineral density Z-score less than or equal to 2.0 accompanied by one or more of the following: 1) at least two long bone fractures by age 10 years; 2) at least three long bone fractures up to age 19 years.NICHD Pediatric TerminologyU.S. National Cancer Institute, 2021
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Reduction of bone mass without alteration in the composition of bone, leading to fractures. Primary osteoporosis can be of two major types: postmenopausal osteoporosis (OSTEOPOROSIS, POSTMENOPAUSAL) and age-related or senile osteoporosis.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Significant thinning and weakening of bones over time, making them vulnerable to breaks.Harvard Dictionary of Health TermsHarvard Medical Publishing, 2011
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A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence.Common Terminology Criteria for Adverse EventsU.S. National Institutes of Health, 2021
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Osteoporosis is a progressive metabolic bone disease that decreases bone mineral density (bone mass per unit volume), with deterioration of bone structure. Skeletal weakness leads to fractures with minor or inapparent trauma, particularly in the thoracic and lumbar spine, wrist, and hip (called fragility fractures). Diagnosis is by...Merck & Co., Inc., 2020
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Osteoporosis, a chronic, progressive disease of multifactorial etiology (see Etiology), is the most common metabolic bone disease in the United States. It has been most frequently recognized in elderly white women, although it does occur in both sexes, all races, and all age groups.WebMD, 2019
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Osteoporosis causes bones to become weak and brittle - so brittle that a fall or even mild stresses such as bending over or coughing can cause a fracture. Osteoporosis-related fractures most commonly occur in the hip, wrist or spine.Mayo Foundation for Medical Education and Research
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Osteoporosis is a complex skeletal disease characterized by low bone density and microarchitectural defects in bone tissue, resulting in increased bone fragility and susceptibility to fracture.Athenahealth, Inc., 2019
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Osteoporosis, disease characterized by the thinning of bones, with a consequent tendency to sustain fractures from minor stresses. Osteoporosis is the most common metabolic bone disease, and its name literally means "porous bone." The disorder is most common in postmenopausal women over age 50. It...Encyclopedia Britannica, Inc., 2020
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