Pharmacologic Substance
phentermine Audio
phen·ter·mine [ fen-ter-meen ]
Brand Names:
Adipex-P; Lomaira; Qsymia
Effect:
Increased Cerebral Cortex Dopamine Activity; Increased Cerebral Cortex Norepinephrine Activity; Increased Sympathetic Activity
May Treat:
Obesity
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to phentermine:
  • A central nervous system stimulant and sympathomimetic with actions and uses similar to those of DEXTROAMPHETAMINE. It has been used most frequently in the treatment of obesity.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A natural monoamine alkaloid derivative and a sympathomimetic stimulant with appetite suppressant property. Phentermine, which was part of the Fen-Phen anti-obesity medication, stimulates hypothalamic release of norepinephrine, a neurotransmitter involved in stress responses (fight-or-flight reactions), and reduces hunger sensation. Phentermine also causes the release of epinephrine or adrenaline outside of the brain, resulting in breakdown of stored fat.
    NCI
    U.S. National Cancer Institute, 2021
  • Central nervous system stimulant and sympathomimetic with actions and uses similar to dextroamphetamine; used in the treatment of obesity.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.