Pharmacologic Substance
amphetamine
am·phet·a·mine [ am-fet-uh-meen, -min ]
Brand Names:
Adderall; Adzenys; Dyanavel; Evekeo; Mydayis
Effect:
Bronchodilation; Increased Cerebral Cortex Dopamine Activity; Increased Cerebral Cortex Norepinephrine Activity
May Treat:
Attention Deficit Disorder with Hyperactivity;
Narcolepsy
More Information:
Definitions related to amphetamine:
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A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A synthetic substance related to natural sympathomimetic amines. Amphetamine appears to exert its central nervous system (CNS) and peripheral effects indirectly by inducing the release of biogenic amines from their storage sites in nerve terminals. This agent is a commonly abused psychostimulant drug, which may be snorted, taken orally, smoked, or injected. Amphetamine induces psychologic dependence which is manifested by elevated mood, increased wakefulness, concentration, physical performance and a feeling of well-being. With sustained use, the effects of tachycardia and enhanced alertness diminish while psychotoxic effects such as hallucinations and delusions may occur. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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Powerful central nervous system stimulant and sympathomimetic with multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase; it is also a drug of abuse and a psychotomimetic.CRISP ThesaurusNational Institutes of Health, 2006
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Amphetamine, prototype of a series of synthetic drugs, all called amphetamines, that have pronounced stimulatory actions on the central nervous system. Amphetamine itself is a colourless liquid with an acrid taste and a faint odour; the most widely used preparation of the drug is amphetamine...Encyclopedia Britannica, Inc., 2020
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