Pharmacologic Substance
phenylephrine Audio
phen·yl·eph·rine [ fen-l-ef-reen, -rin, feen- ]
Brand Names:
4-Way; Afrin Nasal; Alahist D; Aldex CT; Benadryl Allergy Plus Congestion; Benadryl-D Allergy and Sinus; Biorphen; Brovex PBC; B-Tuss; ColdCough PD; Congestaid II; Cyclomydril; Dallergy Reformulated Nov 2011; De-Chlor G; De-Chlor HC; De-Chlor MR; Dytan-D; Dytan-D Chewable; GRX Hemorrhoidal; Hydro GP; Hydron CP; Hydro-PC II; Little Noses Decongestant; Maxiphen CDX; Medicone Hemorrhoidal; M-End PE; Mydfrin; Nariz HC; Nasop; Nasopen PE; Nazarin HC; Neo-Synephrine; Nikzon; Omidria; Poly Hist PD; Prep-Hem; RectiCare Advance Cream; Relasin HC; Rhinall; Simuc-HD; Sudafed PE; Sudogest PE; Sudo-Tab; Triant-HC; Vanatab DM; Vazculep; Ventuss; Wal-Dryl PE; Wal-Dryl-D; Wal-Four; Wal-Phed PE; Zotex C
Effect:
Conjunctival Arterial Vasoconstriction; Decreased Nasal and Sinus Secretions
May Treat:
Fissure in Ano; Glaucoma, Open-Angle; Hemorrhoids; Hypotension; Pruritus Ani; Rhinitis, Vasomotor; Shock, Septic; Tachycardia, Supraventricular
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to phenylephrine:
  • A direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output.
    NCI
    U.S. National Cancer Institute, 2021
  • An alpha-1 adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • Direct acting sympathomimetic amine that stimulates alpha-adrenergic receptors and is a powerful vasoconstrictor.
    CRISP Thesaurus
    National Institutes of Health, 2006
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