Pharmacologic Substance
procaine
pro·caine [ proh-keyn, proh-keyn ]
Effect:
Conduction System Depolarization; Decreased Organized Electrical Activity
May Prevent:
Pain
May Treat:
Pain;
Substance Withdrawal Syndrome
More Information:
Definitions related to procaine:
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A benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.NCI ThesaurusU.S. National Cancer Institute, 2021
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A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1016).NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Local anesthetic of the ester type that has a slow onset and a short duration of action, mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.CRISP ThesaurusNational Institutes of Health, 2006
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