Pharmacologic Substance
ranitidine Audio
ra·nit·i·dine [ ra-nit-i-deen ]
Brand Names:
Wal-Zan; Zantac
Effect:
Decreased Histamine Activity; Inhibition Gastric Acid Secretion
May Prevent:
Duodenal Ulcer; Gastrointestinal Hemorrhage; Stomach Ulcer
May Treat:
Duodenal Ulcer; Esophagitis, Peptic; Gastroesophageal Reflux; Stomach Ulcer; Zollinger-Ellison Syndrome
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to ranitidine:
  • A member of the class of histamine H2-receptor antagonists with antacid activity. Ranitidine is a competitive and reversible inhibitor of the action of histamine, released by enterochromaffin-like (ECL) cells, at the histamine H2-receptors on parietal cells in the stomach, thereby inhibiting the normal and meal-stimulated secretion of stomach acid. In addition, other substances that promote acid secretion have a reduced effect on parietal cells when the H2 receptors are blocked.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A non-imidazole blocker of those histamine receptors that mediate gastric secretion (H2 receptors). It is used to treat gastrointestinal ulcers.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • N-2-(5-dimethylamino)methyl-2- furanylmethyl thioethyl-N'-methyl-2-nitro-1,1 -ethenediamine; cimetidine analog; H2 histamine receptor antagonist used to treat gastric ulcers.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.