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Retinopathy of Prematurity
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Retinopathy of Prematurity (ROP)
National Eye Institute
Related terms:
angioid streak
bronchopulmonary dysplasia
diabetic retinopathy
periventricular leukomalacia
retinal degeneration
retinal detachment
retina disorder
retinal dysplasia
retina hemorrhage
Disease or Syndrome
retinopathy of prematurity
Subclass of:
Infant, Premature, Diseases; Retinal Diseases
Also called:
Retrolental Fibroplasia
Definitions related to retinopathy of prematurity:
  • A bilateral retinopathy characterized by neovascularization, scarring, retinal detachment, and eventually blindness. It may be mild or severe. It occurs in babies born prematurely. Causes include oxygen toxicity and hypoxia.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A rare retinal vasoproliferative disease affecting preterm infants characterized initially by a delay in physiologic retinal vascular development and compromised physiologic vascularity, and subsequently by aberrant angiogenesis in the form of intravitreal neovascularization.
    OrphaNet
    INSERM, 2021
  • A retinal condition of very immature infants that may be characterized by non-vascularized retina that may lead to neovascularization, scarring, retinal detachment, and blindness.
    NICHD Pediatric Terminology
    U.S. National Cancer Institute, 2021
  • An avascular or abnormally vascularized retina that occurs in premature infants and can lead to blindness.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • Bilateral retinopathy typically occurring in premature infants treated with high concentrations of oxygen; characterized by vascular dilation, proliferation, and tortuosity, edema, and retinal detachment with ultimate conversion of the retina into a fibrous mass; usually growth of the eye is arrested and may result in microophthalmia; blindness may occur.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Retinopathy of prematurity is a bilateral disorder of abnormal retinal vascularization in premature infants, especially those of lowest birth weight. Outcomes range from normal vision to blindness. Diagnosis is by ophthalmoscopy. Treatment of severe disease may include cryotherapy, laser photocoagulation, or bevacizumab; other treatment...
    Merck Manuals
    Merck & Co., Inc., 2020
  • Retinopathy of prematurity (ROP) is a serious vasoproliferative disorder that affects extremely premature infants. Retinopathy of prematurity often regresses or heals but can lead to severe visual impairment or blindness.
    Medscape
    WebMD, 2019
  • Retinopathy of prematurity, disease in which retinal blood vessels develop abnormally in the eyes of premature infants. In mild forms of retinopathy of prematurity, developing blood vessels within the retina, which originate at the optic disk, stop growing toward the periphery of the retina for a...
    Encyclopedia Britannica
    Encyclopedia Britannica, Inc., 2020
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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