Pharmacologic Substance
scopolamine
sco·pol·a·mine [ skuh-pol-uh-meen, -min, skoh-puh-lam-in ]
Brand Names:
Donnatal; D-Tal; Isopto Hyoscine; Phenohytro; Transderm Scop
Effect:
Decreased GI Motility; Decreased Histamine Activity; Decreased Nasal and Sinus Secretions; Decreased Parasympathetic Acetylcholine Activity; Decreased Serotonin Activity; Positive Chronotropy; Pupillary Dilation; Salivation Inhibition
May Prevent:
Motion Sickness; Nausea; Vomiting
May Treat:
Colonic Diseases;
Diverticulitis;
Dysentery;
Facial Paralysis;
Iridocyclitis;
Parkinson Disease, Postencephalitic;
Rhinitis, Vasomotor
More Information:
Definitions related to scopolamine:
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A tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.NCI ThesaurusU.S. National Cancer Institute, 2021
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An alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like ATROPINE, but may have more central nervous system effects. Its many uses include an anesthetic premedication, the treatment of URINARY INCONTINENCE and MOTION SICKNESS, an antispasmodic, and a mydriatic and cycloplegic.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Scopolamine, alkaloid drug obtained from a number of plants of the family Solenaceae, including nightshade, henbane, and jimsonweed. Scopolamine is an effective remedy for motion sickness, probably because of its ability to depress the central nervous system (brain and spinal cord). Like atropine...Encyclopedia Britannica, Inc., 2020
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