Pharmacologic Substance
scopolamine hydrobromide
Effect:
Decreased GI Motility; Decreased Histamine Activity; Decreased Nasal and Sinus Secretions; Decreased Parasympathetic Acetylcholine Activity; Decreased Serotonin Activity; Positive Chronotropy; Pupillary Dilation; Salivation Inhibition
May Prevent:
Motion Sickness; Nausea; Vomiting
May Treat:
Colonic Diseases;
Diverticulitis;
Dysentery;
Facial Paralysis;
Iridocyclitis;
Parkinson Disease, Postencephalitic;
Rhinitis, Vasomotor
More Information:
Definitions related to scopolamine hydrobromide:
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The hydrobromide salt form of scopolamine, a tropane alkaloid derived from plants of the nightshade family (Solanaceae), specifically Hyoscyamus niger and Atropa belladonna, with anticholinergic, antiemetic and antivertigo properties. Structurally similar to acetylcholine, scopolamine antagonizes acetylcholine activity mediated by muscarinic receptors located on structures innervated by postganglionic cholinergic nerves as well as on smooth muscles that respond to acetylcholine but lack cholinergic innervation. The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.NCI ThesaurusU.S. National Cancer Institute, 2021
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