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27:39
Squamous Cell Carcinoma and Precursors
Paul Bolin
Related terms:
adenocarcinoma
carcinoma
carcinoma in situ
basal cell carcinoma
basosquamous carcinoma
transitional cell carcinoma
papilloma
adenosquamous carcinoma
verrucous carcinoma
Neoplastic Process
squamous cell carcinoma Audio
[ skway-mus sel kar-sih-noh-muh ]
Subclass of:
Squamous Cell Neoplasms; Carcinoma
Definitions related to squamous cell carcinoma:
  • (carcinoma, squamous cell, malignant) A malignant neoplasm arising from squamous epithelial cells.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Cancer that begins in squamous cells, which are thin, flat cells that look like fish scales. Squamous cells are found in the tissue that forms the surface of the skin, the lining of the hollow organs of the body, and the passages of the respiratory and digestive tracts.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Carcinoma developed from squamous epithelium.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • The presence of squamous cell carcinoma of the skin.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • (carcinoma, squamous cell) A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Squamous cell carcinoma is a malignant tumor of epidermal keratinocytes that invades the dermis; this cancer usually occurs in sun-exposed areas. Local destruction may be extensive, and metastases occur in advanced stages. Diagnosis is by biopsy. Treatment depends on the tumor�s characteristics and may involve curettage and...
    Merck Manuals
    Merck & Co., Inc., 2020
  • Squamous cell carcinoma (SCC) is the second most common skin cancer. SCC most often affects individuals who are exposed to large amounts of sunlight. It is typically characterized by a red papule or plaque with a scaly or crusted surface; it may be suspected whenever a small, firm reddish-colored skin lesion, growth or bump appears on...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
  • Cutaneous squamous cell carcinoma (SCC) is the proliferation of atypical, transformed keratinocytes in the skin with malignant behavior. It ranges from in situ tumors (also known as Bowen disease) to invasive tumors and metastatic disease.Precursor lesions for SCCs are called actinic (or sun-damage) keratosis; this topic is covered in...
    Epocrates
    Athenahealth, Inc., 2019
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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