Pharmacologic Substance
succinylcholine
suc·ci·nyl·cho·line
Brand Names:
Anectine; Quelicin
Effect:
Decreased Striated Muscle Contraction
More Information:
Definitions related to succinylcholine:
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A quaternary ammonium compound and depolarizing agent with short-term muscle relaxant properties. Succinylcholine binds to nicotinic receptors at the neuromuscular junction and opening the ligand-gated channels in the same way as acetylcholine, resulting in depolarization and inhibition of neuromuscular transmission. Depolarization may be prolonged due to succinylcholine's resistance to acetylcholinesterases thereby leading to disorganized muscle contraction followed by skeletal muscle relaxation and flaccid paralysis.NCI ThesaurusU.S. National Cancer Institute, 2021
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A quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. It is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. Succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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