Pharmacologic Substance
succimer
Brand Names:
Chemet
Effect:
Unknown Physiological Effect
May Treat:
Lead Poisoning, Nervous System, Childhood
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to succimer:
  • A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An orally active mercaptodicarboxylic acid, with heavy metal chelating activity. As a strong chelator, succimer is able to bind to heavy metals, such as lead, in the bloodstream, thereby forming a water-soluble complex that can be eliminated via urinary excretion. This prevents heavy metal poisoning. In addition, succimer is able to chelate the alpha particle emitter and radionuclide polonium Po 210 ((Po-210), thereby increasing its excretion and reducing the toxic effects of Po-210.
    NCI
    U.S. National Cancer Institute, 2021
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