Neoplastic Process
gonadoblastoma Audio
[ goh-na-doh-blas-toh-muh ]
Subclass of:
Neoplasms, Germ Cell and Embryonal; Neoplasms, Gonadal Tissue; Gonadal Dysgenesis, 46,XY
Definitions related to gonadoblastoma:
  • A complex neoplasm composed of a mixture of gonadal elements, such as large primordial GERM CELLS, immature SERTOLI CELLS or GRANULOSA CELLS of the sex cord, and gonadal stromal cells. Gonadoblastomas are most often associated with gonadal dysgenesis, 46, XY.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • A mixed germ cell/sex cord-stromal tumor characterized by the presence of large germ cells which resemble seminoma cells and small cells which resemble Sertoli or granulosa cells. It occurs in the testis and the ovary and is identified in children and adults. It is often associated with gonadal dysgenesis and abnormal karyotype.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • The presence of a gonadoblastoma, a neoplasm of a gonad that consists of aggregates of germ cells and sex cord elements.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2021
  • In 1953, Scully first described a unique gonadal neoplasm that strongly resembled a normally developing gonad and subsequently named the neoplasm gonadoblastoma. Gonadoblastoma is a rare benign tumor that has the potential for malignant transformation and affects a subset of patients with an intersex disorder or disorder of sex...
    Medscape
    WebMD, 2019
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