Neoplastic Process
mast-cell sarcoma
mast·cell sar·co·ma
Subclass of:
Mastocytosis
Definitions related to mast-cell sarcoma:
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(mast cell sarcoma) A rare malignant neoplasm characterized by localized but destructive growth of a tumor consisting of highly atypical, immature mast cells. (WHO, 2001)NCI ThesaurusU.S. National Cancer Institute, 2021
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A unifocal malignant tumor that consists of atypical pathological MAST CELLS without systemic involvement. It causes local destructive growth in organs other than in skin or bone marrow.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(mast cell sarcoma) Mast cell sarcoma is a rare, neoplastic disease characterized by locally destructive sarcoma-like growth of a solitary mass, composed of atypical mast cells, and without systemic involvement. It can affect any organ and the symptoms depend on the location. Cells are medium to large, pleomorphic or epithelioid, with oval, bilobed or multilobulated nuclei, sometimes prominent multinucleated giant cells. The disease closely resembles other neoplasms and may share associated markers, however the tumor is positive for mast cell tryptase.OrphaNetINSERM, 2021
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