Biologically Active Substance
prothrombin
pro·throm·bin [ proh-throm-bin ]
Brand Names:
Kcentra
Definitions related to prothrombin:
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A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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Plasma protein precursor of thrombin, converted to thrombin by a prothrombin activator complex; deficiency of prothrombin leads to hypoprothrombinemia.CRISP ThesaurusNational Institutes of Health, 2006
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Clotting factor II, or prothrombin, is a vitamin K�dependent proenzyme that functions in the blood coagulation cascade. Factor II deficiency is a rare, inherited or acquired bleeding disorder.WebMD, 2019
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Prothrombin, glycoprotein (carbohydrate-protein compound) occurring in blood plasma and an essential component of the blood-clotting mechanism. Prothrombin is transformed into thrombin by a clotting factor known as factor X or prothrombinase; thrombin then acts to transform fibrinogen, also present...Encyclopedia Britannica, Inc., 2020
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