-
Annals of Medicine and Surgery (2012) May 2023Case report.
UNLABELLED
Case report.
INTRODUCTION AND IMPORTANCE
The purpose of this study is to report an extremely rare case of PIK3CA-related overgrowth spectrum.
CASE PRESENTATION
A 12-year-old boy presented with severe overgrowth in the left lower limb causing severe movement restriction and decreased quality of life.
INTERVENTIONS AND OUTCOME
Episodes of myiasis were manually treated through mechanical removal and the patient was placed on rapamycin therapy for managing vascular malformations.
CONCLUSION
CLOVES syndrome is a rare overgrowth disorder that can be confused with other overgrowth syndromes; however, clinical and imaging findings are essential for pinpointing the correct diagnosis as genetic sequencing may not always prove reliable.
PubMed: 37229069
DOI: 10.1097/MS9.0000000000000485 -
Clinical Practice and Cases in... Nov 2019Cutaneous maggots are occasionally encountered in the emergency department. We present a case in which maggots were visually identified and ultrasound was used to detect...
Cutaneous maggots are occasionally encountered in the emergency department. We present a case in which maggots were visually identified and ultrasound was used to detect additional maggots below the skin crevices in a patient with elephantiasis nostras verrucosa.
PubMed: 31763611
DOI: 10.5811/cpcem.2019.7.43250 -
The Brazilian Journal of Infectious... 2020Epidermal parasitic skin diseases encompass scabies, pediculosis, cutaneous larva migrans, myiasis, and tungiasis. Tungiasis is probably the most neglected of all... (Review)
Review
Epidermal parasitic skin diseases encompass scabies, pediculosis, cutaneous larva migrans, myiasis, and tungiasis. Tungiasis is probably the most neglected of all Neglected Tropical Diseases (NTD). It occurs in South America, the Caribbean and Sub-Saharan Africa and affects marginalized populations where people live in extreme poverty. In endemic communities the prevalence can be up to 30% in general population and 85% in children. Over time, chronic pathology develops characterized by hyperkeratosis, edema around the nail rim, fissures, ulcers, deformation and loss of nails. This leads to a pattern of disabilities, eventually resulting in impairment of mobility. Dimeticones are a family of silicon oils with a potential to kill parasites located on top or inside the epidermis by a physical mode of action. They are considered the treatment of choice for pediculosis capitis and pediculosis pubis. With regard to tungiasis, the so called rear abdominal cone of the parasites has been identified as a target for treatment with dimeticones. NYDA®, a mixture of two dimeticones with different viscosity, is the only dimeticone product for which data on the mode of action, efficacy and safety with regard to tungiasis exists. The product has been shown highly effective against embedded sand fleas, even in very intense infection with more than 500 parasites situated on top of each other. A randomized controlled trial showed that seven days after a targeted application of NYDA® 97% (95% CI 94-99%) of the embedded sand fleas had lost all signs of viability. Comprehensive toxicological investigations on the dimeticones contained in NYDA® showed that there is practically no risk of embryotoxicity, fetotoxicity, teratogenicity, and other toxicity. The safety of dimeticones was also demonstrated in clinical trials with a total of 106 participants with tungiasis, in which not a single adverse event was observed.
Topics: Animals; Child; Clinical Trials as Topic; Dimethylpolysiloxanes; Female; Humans; Male; Neglected Diseases; Skin Diseases, Parasitic; Tungiasis
PubMed: 32105621
DOI: 10.1016/j.bjid.2020.01.004 -
Case Reports in Obstetrics and... 2023Human myiasis is an infestation produced by fly larvae invading the tissues. We present a case of a 40-year-old virgin woman with vulvar myiasis. She reported at the...
Human myiasis is an infestation produced by fly larvae invading the tissues. We present a case of a 40-year-old virgin woman with vulvar myiasis. She reported at the gynecology clinic with a bloody discharge, severe pain, and swelling of the genital area for six days. Her menstrual history revealed the use of folded clothes. She had no specific gynecological disease. At the examination of the external genitalia, a tender mass measuring 6 cm × 4 cm and an ulcer measuring 1 cm × 1 cm on the surface of the labia majora were found. The patient was hospitalized. Serology, blood, and urine tests were requested; all laboratory tests were normal. The patient was transferred to the operating room (OR) with the diagnosis of necrotizing fasciitis. In the OR, we performed a longitudinal incision on the mass and removed nearly 30 visible maggots. After washing with normal saline, the patient was transferred to the ward without wound suturing. Debridement of the necrotic vulvar mass along with daily washing was performed for 7 days. The wound was sutured on the seventh day at the OR. Antibiotic therapy was continued for 4 days, and the patient was discharged with normal laboratory tests on the eleventh day after admission. We believe that poor sanitary hygiene was the cause of vulvar myiasis in our patient. We conclude that appropriate measures must be taken to reduce the risk of human myiasis, especially in tropical rural regions.
PubMed: 37593321
DOI: 10.1155/2023/5579531 -
Frontiers in Medicine 2019Myasis is the infestation by fly larvae (Diptera) in live vertebrates including humans. Myasis has been reported most commonly in tropical and subtropical areas around...
Myasis is the infestation by fly larvae (Diptera) in live vertebrates including humans. Myasis has been reported most commonly in tropical and subtropical areas around the world with poor sanitation and presence of cattle. Neonatal umbilical myiasis is an important cause of death in bovines and produces major economic losses in the livestock industry. However, its presentation in humans is rare, with a few cases reported worldwide. Moreover, umbilical myasis can be life-treating due to the risk of larvae migration to deeper tissues of the abdomen, omphalitis, and sepsis. We describe the case of a 7-day-old infant admitted to the hospital due to umbilical cord myiasis. In total, 55 larvae were removed from the wound and identified as . The patient recovered satisfactorily after treatment with ivermectin and amoxicillin. A literature search was performed in Pubmed, Medline, Lilacs and Google Scholar, with 64 cases of myasis by being reviewed. Oral cavity, wounds, scalp and natural orifices are the main affected anatomical areas. Risk factors include the extremes of age, male sex, poor hygiene, alcohol and drug use, cancer, and mental disability. Programs for human myiasis prevention and surveillance are needed in neotropical areas where living conditions make it difficult to implement control strategies.
PubMed: 32039212
DOI: 10.3389/fmed.2019.00292 -
Turkiye Parazitolojii Dergisi Jun 2023Myiasis is a parasitic infestation of tissues and body cavities of vertebrates by . Nasal myiasis is mostly caused by the and families. Many predisposing factors play...
Myiasis is a parasitic infestation of tissues and body cavities of vertebrates by . Nasal myiasis is mostly caused by the and families. Many predisposing factors play a role in the appearance of nasal myiasis. In the treatment of the disease, the use of antiseptics together with mechanical cleaning is recommended. In this report, a case of nasopharyngeal myiasis in a 75-year-old patient hospitalized in the intensive care unit is presented. Nine larvae were detected in the patient's nose. Larvae were removed from the area and were cleaned with iodine solution for three days. As a result of macroscopic and microscopic examination, the larvae were identified as the third stage of sp. in order to prevent myiasis infestations, personnel working in places where the patient is unconscious, such as intensive care units, should daily check the patient's body cavities such as nose, mouth and ear cavities, and perform their care and cleaning.
Topics: Animals; Humans; Aged; Sarcophagidae; Diptera; Myiasis; Larva
PubMed: 37249117
DOI: 10.4274/tpd.galenos.2023.86547 -
Journal of Infection in Developing... Nov 2022Furuncular myiasis is a parasitosis of the skin that is commonly reported in the tropical areas and is caused by various agents including Dermatobia hominis. Knowledge...
Furuncular myiasis is a parasitosis of the skin that is commonly reported in the tropical areas and is caused by various agents including Dermatobia hominis. Knowledge of myiasis is limited in Italy, resulting in difficulties in its diagnosis and treatment. We report a case of imported furuncular myiasis in a 48 year old Italian patient who returned from Peru. A third stage larva of D. hominis was identified and the diagnosis of myiasis was confirmed.
Topics: Humans; Middle Aged; Myiasis; Travel; Skin; Italy
PubMed: 36449652
DOI: 10.3855/jidc.17006 -
Parasites & Vectors Jul 2019Oestrosis, caused by the larvae of Oestrus ovis, commonly known as sheep nose bot, is an obligatory cavitary myiasis of sheep and goats. Oestrus ovis is a widespread... (Meta-Analysis)
Meta-Analysis
BACKGROUND
Oestrosis, caused by the larvae of Oestrus ovis, commonly known as sheep nose bot, is an obligatory cavitary myiasis of sheep and goats. Oestrus ovis is a widespread parasite, but little is known about the prevalence of oestrosis at the global and broad geographical levels. The present study aimed to explore the epidemiology of oestrosis at the global and regional level to estimate prevalences and their associated factors using a systematic approach. This is, to the author's knowledge, the first meta-analysis of oestrosis in sheep and goats.
METHODS
Published articles were obtained from nine electronic databases (PubMed, CAB Abstracts, Web of Science, Scopus, UCB library, Medline, Biosis Citation Index, Indian journals and Google Scholar) reporting the prevalence of O. ovis in sheep and goats from 1970 to 2018. Pooled prevalences were estimated using a random effect meta-analysis model.
RESULTS
Sixty-six studies were eligible, and data from 40,870 sheep and 18,216 goats were used for quantitative analysis. The random effect estimated prevalence of oestrosis at the global level in sheep was 51.15% (95% CI: 42.80-59.51%) and in goats was 42.19% (95% CI: 33.43-50.95%). The pooled prevalence estimates for Africa, Asia, Europe and the Americas were 47.85% (95% CI: 36.04-59.66%), 44.48% (95% CI: 33.09-55.87%), 56.83% (95% CI: 48.92-64.74%) and 34.46% (95% CI: 19.90-49.01%), respectively. Heterogeneity (I > 80%) was detected in most pooled estimates.
CONCLUSIONS
Oestrosis is highly prevalent in many geographical regions of the world, especially in Europe and Africa. Factors that contribute to the pooled prevalence estimate of oestrosis need to be emphasised in any survey to estimate the true prevalence of oestrosis. Furthermore, there is a need for immunisation or implementation of other preventive measures to reduce the burden of oestrosis in sheep and goats and to improve the health and welfare status.
Topics: Animals; Databases, Factual; Diptera; Ectoparasitic Infestations; Female; Goat Diseases; Goats; Larva; Male; Myiasis; Nose; Prevalence; Seasons; Sheep; Sheep Diseases
PubMed: 31300017
DOI: 10.1186/s13071-019-3597-2 -
Travel Medicine and Infectious Disease 2023
Topics: Humans; Animals; Female; Child; Male; Myiasis; Diptera; Fathers; Larva
PubMed: 37956728
DOI: 10.1016/j.tmaid.2023.102670 -
International Journal of Surgery Case... May 2022Myiasis is the infestation of humans and vertebrate animals with dipterous larvae. It is a rare clinical condition, mainly observed in vulnerable people living in...
INTRODUCTION
Myiasis is the infestation of humans and vertebrate animals with dipterous larvae. It is a rare clinical condition, mainly observed in vulnerable people living in tropical and subtropical regions.
CASE PRESENTATION
We reported a 2-year-old boy, with history of anemia and psoriasis who was admitted to our department after discovering larvea coming out from the left ear 6 weeks ago. Ear examination revealed a few maggots in the left concha and external auditory canal. A larvea was removed and identified as Musca domestica. Management of this otomyiasis was based on manual maggot removal and regular auditory toilets with povidone iodine.
DISCUSSION
Although rarely reported, clinicians should still suspect aural myiasis in the event of an unexplained otalgia in children, mainly if they are from rural area with poor hygienic conditions.
CONCLUSION
Otomyiasis is mainly reported in tropical rural location in debilitated individuals with low socioeconomic conditions and poor hygiene. Thus prophylactic measures are the most effective means to reduce its incidence.
PubMed: 35468383
DOI: 10.1016/j.ijscr.2022.107108