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Medicina Oral, Patologia Oral Y Cirugia... Jan 2023Burning mouth syndrome is an idiopathic condition characterized by burning pain in a normal-appearing oral mucosa lasting at least four to six months. In the case of... (Review)
Review
BACKGROUND
Burning mouth syndrome is an idiopathic condition characterized by burning pain in a normal-appearing oral mucosa lasting at least four to six months. In the case of secondary burning mouth syndrome is associated with local or systemic factors (such as thyroid disorders) that can cause these symptoms. The aim of this review was to study the relationship between thyroid disorders and burning mouth syndrome.
MATERIAL AND METHODS
The present study followed the PRISMA guidelines. An electronic search strategy was developed for PubMed/Medline, Scopus and Cochrane. The following combination of keywords and Boolean operators were used: Thyroid AND burning mouth; Thyroid AND burning mouth syndrome; Hypothyroidism AND burning mouth; Hypothyroidism AND burning mouth syndrome; Hyperthyroidism AND burning mouth; Hyperthyroidism AND burning mouth syndrome. The results were processed by existing free software in https://www.graphpad.com/. To evaluate the association of the categorical variables we used the Fisher test at a level of significance of p-value ≤ 0,05. As a primary summary measure the Odds Ratio (OR) has been used. To analyze the risk of bias the guidelines of the GRADE guide were used and the grade of evidence was analyzed by the guide of Joanna Briggs Institute: Levels of Evidence and Grades of Recommendations.
RESULTS
After applying the inclusion and exclusion criteria, 5 studies were selected for review. The Chi-square was 10.92 and the Odds Ratio was 3.31 with respect to TSH values with p <0.0001 (Fisher's test). The population of patients with TSH alterations is increased in 80.49% and decreased in 19.51%.
CONCLUSIONS
It can be concluded that thyroid hormone abnormalities are a factor in secondary burning mouth syndrome; specially in patients with hypothyroidism.
Topics: Humans; Burning Mouth Syndrome; Hypothyroidism; Thyroid Hormones; Hyperthyroidism; Thyrotropin
PubMed: 36173716
DOI: 10.4317/medoral.25596 -
Dermatologic Clinics Apr 1996Burning mouth syndrome is a common condition particularly affecting elderly women. Numerous precipitating factors are recognized that lead to a burning sensation in... (Review)
Review
Burning mouth syndrome is a common condition particularly affecting elderly women. Numerous precipitating factors are recognized that lead to a burning sensation in clinically normal mucosa. By taking each precipitating factor into account, a favorable treatment outcome usually can be achieved. This article highlights the significance of precipitating factors in burning mouth syndrome and suggests a treatment protocol based on current scientific evidence.
Topics: Adult; Burning Mouth Syndrome; Child; Female; Humans; Middle Aged
PubMed: 8725589
DOI: 10.1016/s0733-8635(05)70361-2 -
JAMA Otolaryngology-- Head & Neck... Jun 2021
Topics: Burning Mouth Syndrome; Humans
PubMed: 33830201
DOI: 10.1001/jamaoto.2021.0177 -
Advances in Oto-rhino-laryngology 2006Burning mouth syndrome (BMS) has been considered an enigmatic condition because the intensity of pain rarely corresponds to the clinical signs of the disease. As a... (Review)
Review
Burning mouth syndrome (BMS) has been considered an enigmatic condition because the intensity of pain rarely corresponds to the clinical signs of the disease. As a result, BMS patients have variously been labelled as depressed, anxious or hypochondriacal and have often been underserviced by the medical and dental communities. Recently, there has been a resurgence of interest in this disorder with the discovery that the pain of BMS may be neuropathic in origin and originate both centrally and peripherally. This chapter discusses some of our recent understandings of the etiology and pathogenesis of BMS as well as the role of pharmacotherapeutic management in this disorder.
Topics: Burning Mouth Syndrome; Diagnosis, Differential; Humans; Prevalence; Taste Disorders
PubMed: 16733345
DOI: 10.1159/000093766 -
Recenti Progressi in Medicina Feb 2007Burning mouth syndrome (BMS) is characterized by burning sensations of the oral cavity in the absence of abnormalities of the oral mucosa. BMS predominantly affects... (Comparative Study)
Comparative Study Review
Burning mouth syndrome (BMS) is characterized by burning sensations of the oral cavity in the absence of abnormalities of the oral mucosa. BMS predominantly affects middle-aged women. This condition has a multifactorial etiology. Multiple approaches to treatment have been described. This article examines BMS, its related factors, and treatment options.
Topics: Age Factors; Aged; Amines; Analgesics; Anti-Anxiety Agents; Antioxidants; Burning Mouth Syndrome; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Diagnosis, Differential; Female; Gabapentin; Humans; Incidence; Male; Middle Aged; Prevalence; Sex Factors; Thioctic Acid; Vitamin B Complex; gamma-Aminobutyric Acid
PubMed: 17439072
DOI: No ID Found -
American Journal of Dentistry Feb 2022To evaluate whether the prevalence of glossodynia increased among patients affected by COVID-19 compared to other hospital populations.
PURPOSE
To evaluate whether the prevalence of glossodynia increased among patients affected by COVID-19 compared to other hospital populations.
METHODS
The i2b2 patient registry platform at the University of Florida Health Center was used to generate a count of patients using the international classification of diseases (ICD)-10 diagnosis codes from October 2015 to June 2021. Logistic regression of the aggregates was used for analysis.
RESULTS
Of the patients with both glossodynia and COVID-19, 60% were females, 32% were African American, 64% were white, and 100% were adults. There were 72% females, 19% African Americans, 72% whites, and 93% adults with glossodynia only. For COVID-19 patients, 57% were females, 23% were African American, 56% whites, and 90% were adults. The odds ratio (OR) for glossodynia in the COVID-19 patients was significant (OR = 2.9; 95% CI, 1.94-4.32; P < 0.0001).
CLINICAL SIGNIFICANCE
Glossodynia is significantly more common in COVID-19 patients and should be considered in the differential diagnoses among the oral complications of this infection.
Topics: Adult; Black or African American; Burning Mouth Syndrome; COVID-19; Female; Glossalgia; Humans; Male; White People
PubMed: 35316585
DOI: No ID Found -
Clinical Evidence Jun 2003
Review
Topics: Antidepressive Agents; Burning Mouth Syndrome; Cognitive Behavioral Therapy; Humans
PubMed: 15366199
DOI: No ID Found -
British Dental Journal Nov 2022
Topics: Humans; Burning Mouth Syndrome
PubMed: 36434235
DOI: 10.1038/s41415-022-5275-6 -
Frontiers in Bioscience (Elite Edition) Jan 2016Burning mouth syndrome (BMS) is characterised by the presence of a burning sensation in the oral mucosa in the absence of any clinically apparent mucosal sign. It occurs... (Review)
Review
Burning mouth syndrome (BMS) is characterised by the presence of a burning sensation in the oral mucosa in the absence of any clinically apparent mucosal sign. It occurs more commonly in older women and often affects the tongue tip and lateral borders, lips, and hard and soft palates. Besides the burning sensation, patients with BMS may complain of unremitting oral mucosal pain, dysgeusia, and xerostomia. The exact pathophysiology of primary BMS remains unknown. A major challenge for the clinician is the treatment of BMS: identifying possible causative factors is the first step, but BMS is often idiopathic. Drug therapy, in addition to behavioural therapy and psychotherapy, may help to eliminate the symptoms. Considering the growing incidence of BMS in older people, further research is required to determine the true efficacy of current management strategies for patients with this disorder.
Topics: Benzylamines; Burning Mouth Syndrome; Capsaicin; Clonazepam; Humans; Lidocaine; Prevalence
PubMed: 26709657
DOI: 10.2741/E762 -
Dermatologic Clinics Jan 2003Burning mouth syndrome is the occurrence of oral pain in a patient with a normal oral mucosal examination. It can be caused by both organic and psychologic or... (Review)
Review
Burning mouth syndrome is the occurrence of oral pain in a patient with a normal oral mucosal examination. It can be caused by both organic and psychologic or psychiatric factors, which can be broken down into local, systemic. psychologic or psychiatric, and idiopathic causes. The most frequently associated conditions are psychiatric (depression, anxiety, or cancerphobia); xerostomia; nutritional deficiency; allergic contact dermatitis; candidiasis; denture-related pain: and parafunctional behavior. Multiple different factors contributing to the oral pain are common, and a systematic approach to the evaluation is important. Identification of correctable causes of BMS should be emphasized and psychiatric causes should not be invoked without thorough evaluation of the patient. A directed history and careful oral examination must be completed to exclude local diseases and identify clues to potential causes. Assessment of medications, psychiatric history and background, and selected laboratory and patch tests may help identify the etiologies of these symptoms. Treatment should be tailored to each patient and may best be managed in a multidisciplinary approach with input from dermatologists, dentists, psychiatrists. otorhinolaryngologists, and primary care providers. A thoughtful and structured evaluation of the patient with BMS has been associated with improvement in about 70% of patients. The remaining patients may benefit from empiric therapy with a chronic pain protocol and continued supportive interactions.
Topics: Burning Mouth Syndrome; Humans
PubMed: 12622276
DOI: 10.1016/s0733-8635(02)00063-3