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The Western Journal of Medicine Oct 1990We studied 8 adult patients with variable symptoms of cough, dyspnea, stridor, wheezing, or hemoptysis. Fiberoptic bronchoscopy in all showed complete or nearly complete...
We studied 8 adult patients with variable symptoms of cough, dyspnea, stridor, wheezing, or hemoptysis. Fiberoptic bronchoscopy in all showed complete or nearly complete endobronchial obstruction of a main-stem bronchus by neoplasm with a mean bronchial diameter of 1.9 mm +/- 1.6 mm (mean +/- standard deviation). In 4 patients, a lobar bronchus was also completely obstructed. No mass was visible on chest radiographs of any patient; however, computed tomography in each showed main-stem endobronchial obstruction, lobar obstruction (4 instances in 3 patients), and in 6 patients hypoperfusion of the involved lung. Computed tomographic scan showed additional abnormalities that were unsuspected on viewing chest radiographs or at bronchoscopy, including mediastinal adenopathy in 3 patients and an extraluminal tumor component in 4. After therapy with Nd-YAG laser, main-stem airway diameter increased to a mean of 9.6 mm +/- 1.0 mm (P less than .05) and pulmonary functions improved. Results suggest the complementary role of computed tomography and fiberoptic bronchoscopy in the detection and laser-treatment planning of chest radiographically occult severe neoplastic obstruction of the main-stem bronchus.
Topics: Bronchial Neoplasms; Bronchoscopy; Fiber Optic Technology; Humans; Laser Therapy; Radiography, Thoracic; Tomography, X-Ray Computed
PubMed: 2244372
DOI: No ID Found -
ORL; Journal For Oto-rhino-laryngology... 198199 pulmonary resections for benign tumors were performed during the period 1967-1978. 4 patients showed bronchial papilloma. Solitary papilloma of the bronchus is one of...
99 pulmonary resections for benign tumors were performed during the period 1967-1978. 4 patients showed bronchial papilloma. Solitary papilloma of the bronchus is one of the rarest benign tumors; the differences of multiple papillomatosis and inflammatory polyp are stressed. Malignant change was observed in 3 of the 4 cases. The 4 patients presented a 2- to 5-year history of hemoptysis episodes and radiographic aspects characterized by intermittent atelectasis. Radical surgery is the only satisfactory therapy; endoscopic removal of the neoplasm is often incomplete and unsatisfactory.
Topics: Aged; Bronchial Neoplasms; Humans; Male; Middle Aged; Papilloma; Smoking
PubMed: 7301318
DOI: 10.1159/000275550 -
Khirurgiia 2021To analyze the long-term outcomes of local resections in patients with carcinoid tumors of bronchopulmonary system.
OBJECTIVE
To analyze the long-term outcomes of local resections in patients with carcinoid tumors of bronchopulmonary system.
MATERIAL AND METHODS
There were 52 patients with tracheal and bronchopulmonary carcinoid for the period 2013-2019. The sample included 21 men and 31 women. Age of patients ranged from 20 to 82 years (mean 62 years). Typical carcinoid was diagnosed in 34 cases, atypical carcinoid - in 18 cases. Central tumor was diagnosed in 26 patients. Tracheal neoplasm was found in 2 patients. Another patient had mediastinal tumor. Five patients underwent resection with broncho- or tracheobronchoplastic reconstruction.
RESULTS
Surgical approach for carcinoid is determined by its differentiation, localization and lung tissue lesion following a long-standing tumor. These operations are quite safe. Complications occurred after 4 (7.7%) surgeries. Long-term results were followed-up for the period from 8 months to 7 years. There were no signs of recurrence and disease progression after organ-sparing bronchial resection. Local resection with bronchoplasty is advisable for typical carcinoid.
Topics: Adult; Aged; Aged, 80 and over; Bronchi; Bronchial Neoplasms; Carcinoid Tumor; Female; Humans; Lung; Male; Middle Aged; Neoplasm Recurrence, Local; Pneumonectomy; Trachea; Young Adult
PubMed: 34480449
DOI: 10.17116/hirurgia20210915 -
British Medical Journal Apr 1977
Comparative Study
Topics: Bone Neoplasms; Bronchial Neoplasms; Humans; Neoplasm Metastasis; Radiography; Radionuclide Imaging
PubMed: 851819
DOI: 10.1136/bmj.1.6067.1004 -
Critical Reviews in Diagnostic Imaging 1991The most common cause of RUL atelectasis in adults is neoplasm obstructing the RUL bronchus. Scarring of the lobe following chronic infection comes next. Other causes of... (Review)
Review
The most common cause of RUL atelectasis in adults is neoplasm obstructing the RUL bronchus. Scarring of the lobe following chronic infection comes next. Other causes of obstruction, whether central or peripheral, are less common. The only direct sign of atelectasis is approximation of the fissures. All other signs are indirect. Increased density of the collapsed lobe is the most noticeable indirect sign. In the absence of adhesions the RUL is fixed at the hilum only. Therefore, it may take any one of the different shapes. Usually it is not difficult to recognize the dense shrunken lobe. Otherwise, we will have to depend on the other indirect signs, namely, displacement of mediastinal structures, elevation of the right hemidiaphragm, juxtaphrenic peak, elevation of hilum, "disappearance" of RUL artery, changes in position of of vascular (and bronchial) markings, and displacement of granuloma (if present).
Topics: Bronchial Neoplasms; Constriction, Pathologic; Humans; Lung; Pulmonary Atelectasis; Tomography, X-Ray Computed; Torsion Abnormality
PubMed: 1863348
DOI: No ID Found -
Polish Medical Journal 1968
Topics: Adenoma; Adult; Bronchial Neoplasms; Bronchoscopy; Female; Humans; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Metastasis
PubMed: 5650189
DOI: No ID Found -
Thorax Mar 1968From a retrospective review of 4,000 patients with bronchial carcinoma, managed in the Thoracic Surgical Unit in Edinburgh, the salient features of presentation,...
From a retrospective review of 4,000 patients with bronchial carcinoma, managed in the Thoracic Surgical Unit in Edinburgh, the salient features of presentation, surgical management, and the natural history in those unsuitable for surgical management are reviewed.
Topics: Adult; Aged; Bronchial Neoplasms; Female; Humans; Male; Middle Aged; Morbidity; Radiography; Statistics as Topic
PubMed: 5654070
DOI: 10.1136/thx.23.2.136 -
Future Oncology (London, England) Aug 2019In this study, we evaluated the association between tumor location and prognosis in non-small-cell lung cancer patients. The SEER database was used to screen for...
In this study, we evaluated the association between tumor location and prognosis in non-small-cell lung cancer patients. The SEER database was used to screen for suitable patients using our inclusion criteria. The χ test was used to compare baseline patient characteristics and the Kaplan-Meier method as well as the log-rank test were used to compare survival differences. At last, univariate and multivariate Cox proportional hazards regression models were used to analyze the influence of different variables on overall survival. The results found no significant difference in overall survival between patients in laterality (p = 0.071). However, patients with main bronchial tumors had worse prognosis than tumors at other locations (p < 0.001). Our results also showed that tumor location including main bronchus, upper lobe, middle lobe, lower lobe and overlapping lesion was a significant factor affecting survival (p < 0.001). Subgroup analysis revealed that regardless of histology or M stage, patients with main bronchial tumors had a worse survival compared with other tumor locations (all; p < 0.001). Interestingly, we found that patients with tumor main bronchial tumors were more likely to be squamous carcinoma and terminal Tumor, Node, Metastasis stage (all; p < 0.001). Non-small-cell lung cancer patients' prognosis was related to the tumor location. And patients with tumors located in main bronchus had worse outcomes than those located in other locations. Tumor primary site should be considered in treatment management and prognosis assessment.
Topics: Aged; Bronchi; Bronchial Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Lung; Lung Neoplasms; Male; Neoplasm Staging; Prognosis; Proportional Hazards Models
PubMed: 31393163
DOI: 10.2217/fon-2019-0098 -
Cancer Letters Dec 1990Adenocarcinomas induced in canine bronchial segments placed subcutaneously have bronchiolo-alveolar regions. Immunocytochemistry and routine staining of adjacent...
Adenocarcinomas induced in canine bronchial segments placed subcutaneously have bronchiolo-alveolar regions. Immunocytochemistry and routine staining of adjacent sections strongly suggests that the lining of these regions consists of type II cells. These regions may thus represent true prospective alveolar regions, as also seen in embryonic lungs. This first observation of bronchoalveolar cancer arising from a major bronchus indicates that the carcinogen-induced neoplastic progression in bronchial epithelium may lead to type II cell differentiation and type II cell tumor development. The preservation of cell properties in serial nude mouse transplants suggests that it is a stable type II cell population.
Topics: Adenocarcinoma; Animals; Antibodies; Bronchial Neoplasms; Cattle; Dogs; Humans; Immunohistochemistry; Lung Neoplasms; Mice; Neoplasm Transplantation; Pulmonary Alveoli; Pulmonary Surfactants
PubMed: 2257536
DOI: 10.1016/0304-3835(90)90116-f -
Interactive Cardiovascular and Thoracic... Aug 2013Bronchopulmonary carcinoid tumours are relatively uncommon primary lung neoplasms. A small proportion of these lesions are predominantly endobronchial and do not extend...
OBJECTIVES
Bronchopulmonary carcinoid tumours are relatively uncommon primary lung neoplasms. A small proportion of these lesions are predominantly endobronchial and do not extend beyond the bronchial wall. Endoscopic resection can be performed, but carries around a one in three risk of local recurrence and, therefore, mandates long-term surveillance. An alternative is complete surgical resection via bronchoplastic resection. We present our experience of surgical resection in patients with endobronchial carcinoids.
METHODS
From 2000 to 2010, 13 patients (age 45±16 years, 10 males) underwent pure bronchoplastic resection, including systematic nodal dissection, for endobronchial carcinoid tumours, without the resection of lung parenchyma.
RESULTS
There was no significant operative morbidity or mortality. This is a retrospective review of a consecutive case series. The last follow-up for all patients was obtained in 2011. The mean maximum tumour size was 18±8 mm. No lymph node invasion was observed. The median follow-up was 6.3±3.3 years, with no regional recurrence. In 1 case, a tumourlet was identified at 5 years in the contralateral airway and viewed as a metachronous new lesion.
CONCLUSIONS
Bronchial sleeve resection is a safe procedure for suitably located endobronchial carcinoid tumours. Endoscopic resection should be reserved for patients who decline, or are unfit, for surgery.
Topics: Adolescent; Adult; Aged; Bronchial Neoplasms; Carcinoid Tumor; Female; Humans; Lymph Node Excision; Male; Middle Aged; Neoplasm Staging; Pulmonary Surgical Procedures; Retrospective Studies; Time Factors; Treatment Outcome; Tumor Burden; Young Adult
PubMed: 23628650
DOI: 10.1093/icvts/ivt154