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The Journal of Thoracic and... Sep 1993Endobronchial metastases from nonpulmonary neoplasms are rare. Since 1971, we have treated 23 patients with endobronchial metastases, the findings for which form the...
Endobronchial metastases from nonpulmonary neoplasms are rare. Since 1971, we have treated 23 patients with endobronchial metastases, the findings for which form the basis of this article. Many types of primary tumors are capable of endobronchial metastases, although breast, colon, and renal carcinomas predominate. The mean time from the diagnosis of the primary carcinoma to the diagnosis of endobronchial metastases was 59.9 months. Bronchoscopic results were diagnostic in all cases. Although the mean time for the appearance of endobronchial metastases is almost 5 years, on examination the majority of patients will have symptomatic extrabronchial metastatic disease, the quality of their survival will often be poor, and their survival time will be limited (12.5 months). Surgical resection should be confined to patients with localized disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bronchial Neoplasms; Bronchoscopy; Female; Humans; Male; Middle Aged; Retrospective Studies
PubMed: 8361198
DOI: No ID Found -
Pediatric Pulmonology Nov 2000Persistent atelectasis and recurrent pneumonia in the same location should raise suspicion of congenital anomalies or obstructing lesions of the bronchus leading to the... (Review)
Review
Persistent atelectasis and recurrent pneumonia in the same location should raise suspicion of congenital anomalies or obstructing lesions of the bronchus leading to the affected area. We present an 8-year-old black female with a history of recurrent fever, cough, atelectasis of the right middle and lower lobes, and weight loss for several months. Flexible bronchoscopy revealed a polypoid mass obstructing the bronchus intermedius. Biopsy of the neoplasm demonstrated a granular cell tumor (GCT). The patient had a lobectomy of the right lower and middle lobes. She had no recurrence of the tumor after several years of follow-up.
Topics: Biopsy; Bronchi; Bronchial Neoplasms; Bronchoscopy; Child; Female; Follow-Up Studies; Granular Cell Tumor; Humans; Pneumonia; Pulmonary Atelectasis
PubMed: 11064434
DOI: 10.1002/1099-0496(200011)30:5<425::aid-ppul9>3.0.co;2-1 -
The Annals of Thoracic Surgery Jan 1972
Review
Topics: Adult; Aged; Antineoplastic Agents; Biopsy; Bradykinin; Bronchi; Bronchial Neoplasms; Carcinoid Tumor; Carcinoma, Adenoid Cystic; Child, Preschool; Diagnosis, Differential; Female; Hemoptysis; Hormones; Humans; Male; Middle Aged; Neoplasm Metastasis; Pregnancy; Serotonin; Sex Factors
PubMed: 4332934
DOI: 10.1016/s0003-4975(10)64813-8 -
Annals of Surgery Jun 1968
Topics: Adenoma; Bronchial Neoplasms; Carcinoma, Adenoid Cystic; Female; Humans; Male; Methods; Myoepithelioma; Neoplasm Metastasis
PubMed: 4297365
DOI: 10.1097/00000658-196806000-00008 -
Head and Neck Pathology Dec 2017Hyalinizing clear cell carcinoma (HCCC) is an uncommon low-grade minor salivary gland neoplasm that usually arises in the head and neck region. We report a 55-year-old...
Hyalinizing clear cell carcinoma (HCCC) is an uncommon low-grade minor salivary gland neoplasm that usually arises in the head and neck region. We report a 55-year-old man who presented with a 2.5 cm lung mass that was partially obstructing the right bronchus intermedius. The tumor consisted of cords and nests of clear and eosinophilic cells in a hyalinized stromal background. The neoplastic cells expressed cytokeratin (CK) 7, CK 5/6, high-molecular weight cytokeratin (34BE12), p63 and p40, while TTF-1, napsin A, CK20, S100, smooth muscle actin, synaptophysin and chromogranin were negative. Mucicarmine stain also was negative in the lesional cells. Fluorescence in situ hybridization using break apart probes revealed rearrangement of the Ewing Sarcoma Breakpoint Region 1 gene locus. The morphologic, immunophenotypic and cytogenetic findings confirmed the diagnosis of HCCC, most likely of bronchial submucosal gland origin. To our knowledge, only two other reports of primary pulmonary HCCC are available in English literature.
Topics: Adenocarcinoma, Clear Cell; Bronchial Neoplasms; Humans; Male; Middle Aged
PubMed: 28508996
DOI: 10.1007/s12105-017-0820-3 -
Southern Medical Journal Dec 2009: Bronchus-associated Lymphoid Tissue (BALT) lymphomas are a rare type of extranodal marginal zone lymphomas. They comprise 1% of lymphomas and more than two-thirds of...
BACKGROUND
: Bronchus-associated Lymphoid Tissue (BALT) lymphomas are a rare type of extranodal marginal zone lymphomas. They comprise 1% of lymphomas and more than two-thirds of all primary non-Hodgkin lymphoma (NHL) of the lung. BALT lymphomas arise from the bronchus-associated lymphoid tissue.
METHODS
This report describes five cases of BALT lymphoma and discusses the pathogenesis, diagnosis, prognosis and treatment of BALT lymphomas.
RESULTS
In our cohort of patients, patients were managed with surgery, watchful waiting, chemotherapy, immunotherapy, and chemoimmunotherapy. The outcomes are excellent and projected 5-year survival is 100%.
DISCUSSION
BALT lymphomas are associated with chronic inflammation, and they are often asymptomatic. They have an indolent course and the survival outcome is excellent with different treatment modalities such as surgery, watchful waiting, radiotherapy, chemotherapy, immunotherapy or chemoimmunotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bronchial Neoplasms; Female; Humans; Immunotherapy; Lymphoma, B-Cell, Marginal Zone; Male; Middle Aged; Neoplasm Staging; Prognosis; Survival Analysis; Tomography, X-Ray Computed; Treatment Outcome
PubMed: 20016430
DOI: 10.1097/SMJ.0b013e3181bfdd2d -
Journal of Pediatric Surgery Sep 1993Nine children (6 boys, 3 girls) were diagnosed with a primary endobronchial or pulmonary parenchymal neoplasm. The average age at diagnosis was 9 years. Presenting... (Review)
Review
Nine children (6 boys, 3 girls) were diagnosed with a primary endobronchial or pulmonary parenchymal neoplasm. The average age at diagnosis was 9 years. Presenting complaints included cough (7), fever (5), pulmonary infection (3), respiratory distress (3), weight loss (2), pain (2), and hemoptysis (1). Pulmonary x-rays showed persistent atelectasis, pneumonic infiltrates or mass lesions. A computed tomography scan was performed in 8. Five of six endobronchial tumors were diagnosed with bronchoscopy and biopsy. Treatment consisted of thoracotomy and pulmonary resection in 7 cases and laser resection in 2. The pathologic diagnoses were bronchial carcinoid (3), bronchial mucoepidermoid carcinoma (1), inflammatory pseudotumor (plasma cell granuloma) of the bronchus (2) and of the lung parenchyma (1), fibrosarcoma (1), and rhabdomyosarcoma (1). Postoperative chemotherapy was given only to the patient with pulmonary rhabdomyosarcoma; this child died. One child has developed a local recurrence while 7 children are alive and free of disease at an average of 2.4 years postresection. Pulmonary neoplasms are unusual in the pediatric age group and represent a wide spectrum of pathology. Including the present series, 383 tumors have been described. Seventy-six percent were malignant. Early investigation and surgical intervention are essential in children with persistent pulmonary symptoms or x-ray abnormalities. In most cases, the prognosis is excellent with complete surgical resection; however, malignancies other than bronchial adenoma are associated with significantly mortality.
Topics: Bronchial Neoplasms; Carcinoid Tumor; Child; Female; Humans; Lung Neoplasms; Male; Plasma Cell Granuloma, Pulmonary
PubMed: 8308677
DOI: 10.1016/0022-3468(93)90147-d -
Journal of Clinical Pathology Jul 1965The cause of asthmatic attacks in a middle-aged man was disclosed and the relief of his symptoms achieved at one and the same time when he coughed up a tumour which...
The cause of asthmatic attacks in a middle-aged man was disclosed and the relief of his symptoms achieved at one and the same time when he coughed up a tumour which proved to be a solitary bronchial papilloma. The pedicle of the tumour had ruptured as the result of infarction due to thrombosis in stromal blood vessels. Asthmatic attacks, stromal blood vessel thrombosis, and the coughing up of the tumour are three features which have not been reported in the few published accounts of this exceedingly rare bronchial tumour.
Topics: Asthma; Bronchi; Bronchial Neoplasms; Disclosure; Humans; Male; Middle Aged; Neoplasms; Papilloma; Pulmonary Embolism
PubMed: 14318687
DOI: 10.1136/jcp.18.4.401 -
Mayo Clinic Proceedings Aug 1993Bronchial carcinoid tumors, termed (incorrectly) "bronchial adenomas" in the past, are uncommon pulmonary neoplasms. These tumors are currently classified as... (Review)
Review
Bronchial carcinoid tumors, termed (incorrectly) "bronchial adenomas" in the past, are uncommon pulmonary neoplasms. These tumors are currently classified as neuroendocrine in origin because of their potential to form and sometimes secrete a variety of chemical substances. Overall, approximately 75% of bronchial carcinoid tumors arise in the lobar bronchi, 10% occur in the main-stem bronchi, and 15% originate in the periphery of the lung. Well-differentiated carcinoid tumors constitute almost 90% of all bronchial carcinoids. Atypical carcinoid tumors have a higher malignant potential than do typical bronchial carcinoids. The carcinoid syndrome is rarely, if ever, associated with carcinoids limited to the tracheobronchial tree. Occasionally, Cushing's syndrome due to ectopic hormone production is caused by bronchial carcinoid tumors. More than 75% of bronchial carcinoids are detected on conventional posteroanterior chest roentgenograms. Computed tomography may help disclose small neoplasms that are occult on conventional roentgenography, particularly in the assessment of patients who have Cushing's syndrome due to ectopic hormone production. Pulmonary resection is the treatment of choice for bronchial carcinoids. The prognosis is related to the pathologic grade and stage of the tumor.
Topics: Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Humans; Neurosecretory Systems; Syndrome
PubMed: 8331983
DOI: 10.1016/s0025-6196(12)60641-7 -
Revista Portuguesa de Pneumologia 2012Pulmonary myxoma is an extremely rare benign neoplasm. It is mostly parenchymal but may occasionally occur within the tracheobronchial tree. There are very few reports...
INTRODUCTION
Pulmonary myxoma is an extremely rare benign neoplasm. It is mostly parenchymal but may occasionally occur within the tracheobronchial tree. There are very few reports of endobronchial myxoma.
CASE REPORT
We describe a case of endobronchial myxoma in a 40-year-old female patient with a history of asthma and repeated right-sided pneumonia. Thoracic computed tomography (CT) showed medium lobe atelectasis. Fiber optic bronchoscopy revealed a polypoid, well-circumscribed tumor, causing total obstruction of the medium lobe bronchus. Biopsy of the mass was non-diagnostic. Further study included a positron emission tomography (PET) which demonstrated low metabolic activity of the tumor and no evidence of neoplasia in other location. The patient was submitted to a medium lobectomy and microscopic examination of the tumor revealed myxoid stroma with lobulated pattern, elongated and stellate cells, compatible with myxoma.
CONCLUSION
Pulmonary myxoma is extraordinary rare and endobronchial location is very few reported in medical literature.
Topics: Adult; Bronchial Neoplasms; Female; Humans; Myxoma
PubMed: 22261261
DOI: 10.1016/j.rppneu.2011.12.004