Did you mean: bowen s disease
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Acta Dermatovenerologica Croatica : ADC Jun 2018Bowen's disease, named after John Templeton Bowen, also known as squamous cell carcinoma in situ is a type of non-melanocytic intraepidermal malignancy. It is estimated... (Review)
Review
Bowen's disease, named after John Templeton Bowen, also known as squamous cell carcinoma in situ is a type of non-melanocytic intraepidermal malignancy. It is estimated that in general population around 3% to 5% of Bowen's disease transform into invasive squamous cell cancer. Dermoscopy aims in the identification of the Bowen's disease. The most typical dermoscopic features of Bowen's disease include glomerular vessels and scaly surface. Although dermoscopy of Bowen's disease has been well established other skin lesions may present similar or identical structures in dermoscpic images leading to differential diagnosis dilemmas. Histopathological confirmation should be obtained prior the treatment of suspected cases of Bowen's disease in order to avoid a misdiagnosis.
Topics: Bowen's Disease; Dermoscopy; Humans; Skin Neoplasms
PubMed: 29989873
DOI: No ID Found -
BMJ (Clinical Research Ed.) Mar 2020
Topics: Aged; Bowen's Disease; Cautery; Cryotherapy; Curettage; Disease Management; Female; Fluorouracil; Humans; Practice Guidelines as Topic
PubMed: 32198148
DOI: 10.1136/bmj.m813 -
CMAJ : Canadian Medical Association... Nov 2017
Topics: Bowen's Disease; Dermoscopy; Epidermis; Female; Humans; Keratosis, Seborrheic; Middle Aged; Skin Neoplasms
PubMed: 29180387
DOI: 10.1503/cmaj.170810 -
Photodiagnosis and Photodynamic Therapy Jun 2019Although surgical removal is the treatment of choice in Bowen's disease (BD), there are cases in which by age, comorbidities, use of anticoagulants, location, cosmetic... (Clinical Trial)
Clinical Trial Observational Study
BACKGROUND
Although surgical removal is the treatment of choice in Bowen's disease (BD), there are cases in which by age, comorbidities, use of anticoagulants, location, cosmetic result, or size, it is preferable to use other treatments such as cryotherapy, 5-fluorouracil cream, imiquimod 5% cream or photodynamic therapy (PDT). Efficacy of PDT in BD is supported by substantial research and clinical data.
OBJECTIVES
This study aimed to evaluate the long term effectiveness of methyl aminolevulinate-PDT (MAL/PDT) on a wide range of Bowen lesions in different locations and sizes.
METHODS
Patients diagnosed with BD were treated in 3 sessions with a 4-week interval in between with MAL/PDT between January 2016 and January 2017 in a private clinic. Clinical response and relevant patient and tumour characteristics were analyzed during the first year after start of the PDT sessions.
RESULTS
In total, 21 BD lesions in 18 patients were included in the study. Complete regression (CR) after 3rd PDT session was 87.5% and 100% at the 6-month follow-up. Treatment was well tolerated and local adverse reactions were very scarce. No recurrence was observed at 12-month follow-up. Cosmetic outcome at 12 months was good or excellent in 100% of patients.
CONCLUSIONS
MAL/PDT is an effective, non invasive and safe treatment modality for BD with excellent cosmesis.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Female; Humans; Male; Middle Aged; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms
PubMed: 30986539
DOI: 10.1016/j.pdpdt.2019.04.011 -
Giornale Italiano Di Dermatologia E... Oct 2016
Topics: Bowen's Disease; Female; Fingers; Humans; Middle Aged; Skin Neoplasms
PubMed: 27595211
DOI: No ID Found -
CMAJ : Canadian Medical Association... Sep 2006
Topics: Aged; Bowen's Disease; Diagnosis, Differential; Humans; Male; Skin Neoplasms
PubMed: 17001052
DOI: 10.1503/cmaj.060223 -
JAMA Dermatology Aug 2022
Topics: Bowen's Disease; Humans; Nail Diseases; Nails; Skin Neoplasms
PubMed: 35704309
DOI: 10.1001/jamadermatol.2022.2030 -
Journal of the American Academy of... Aug 2022
Review
Topics: Bowen's Disease; Humans; Skin Diseases; Skin Neoplasms
PubMed: 34998961
DOI: 10.1016/j.jaad.2021.12.045 -
Diseases of the Colon and Rectum Jun 1988Thirty-three patients with perianal Bowen's disease were treated at the Cleveland Clinic Foundation from 1954 to 1986. Twenty-one patients were women and 12 were men,... (Review)
Review
Thirty-three patients with perianal Bowen's disease were treated at the Cleveland Clinic Foundation from 1954 to 1986. Twenty-one patients were women and 12 were men, ranging in age from 30 to 69 years (mean, 48 years). Twenty patients (61 percent) presented with symptomatic perianal disease, while 13 patients (39 percent) were noted as having perianal Bowen's disease upon pathologic examination of routine hemorrhoidectomy specimens. Ten of the patients (30 percent) had prior histories of unrelated cancer. Twenty-seven patients were managed by wide local excision, three patients by simple excision, three patients by fulguration, and one patient by an abdominoperineal resection. During a follow-up period averaging 3.7 years (range, 0.3 to 10 years), one patient developed a new invasive skin cancer while a second patient experienced a recurrence of perianal Bowen's disease. The characteristic gross appearance of this lesion and its failure to respond to conventional therapy should prompt the performance of a biopsy, which readily establishes the diagnosis. This experience confirms that wide local excision is adequate therapy for perianal Bowen's disease and that close clinical follow-up is necessary to identify disease recurrence or the development of a malignancy.
Topics: Adult; Aged; Anal Canal; Bowen's Disease; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Perineum; Skin Neoplasms
PubMed: 3288448
DOI: 10.1007/BF02552608 -
CA: a Cancer Journal For Clinicians 1990
Review
Topics: Bowen's Disease; Carcinoma, Squamous Cell; Humans; Skin Neoplasms
PubMed: 2114203
DOI: 10.3322/canjclin.40.4.237