-
Current Opinion in Neurobiology Apr 2017Neuroscience has come to mean the study of electrophysiology of neurons and synapses, micro and macro-scale neuroanatomy, and the functional organization of brain areas.... (Review)
Review
Neuroscience has come to mean the study of electrophysiology of neurons and synapses, micro and macro-scale neuroanatomy, and the functional organization of brain areas. The molecular axis of the field, as reflected in textbooks, often includes only descriptions of the structure and function of individual channels and receptor proteins, and the extracellular signals that guide development and repair. Studies of cytosolic 'molecular machines', large assemblies of proteins that orchestrate regulation of neuronal functions, have been neglected. However, a complete understanding of brain function that will enable new strategies for treatment of the most intractable neural disorders will require that in vitro biochemical studies of molecular machines be reintegrated into the field of neuroscience.
Topics: Biochemistry; Brain; Humans; Nervous System Diseases; Neurons; Neurosciences
PubMed: 28160757
DOI: 10.1016/j.conb.2017.01.004 -
Biochemistry Nov 2021
Topics: Anniversaries and Special Events; Biochemistry; History, 20th Century; History, 21st Century; Publishing
PubMed: 34809432
DOI: 10.1021/acs.biochem.1c00651 -
Biochemistry Jan 2019
Topics: Biochemistry; Humans; International Cooperation; Periodicals as Topic
PubMed: 30702284
DOI: 10.1021/acs.biochem.8b01293 -
Biochemistry Jan 2018
Topics: Animals; Biochemistry; Humans
PubMed: 29310439
DOI: 10.1021/acs.biochem.7b01259 -
Nature Reviews. Molecular Cell Biology Mar 2001The revolution in molecular biology that began nearly 50 years ago has had an enormous impact in the lab, but it also triggered a quieter revolution in undergraduate... (Review)
Review
The revolution in molecular biology that began nearly 50 years ago has had an enormous impact in the lab, but it also triggered a quieter revolution in undergraduate teaching. How has it affected the content and teaching methodology of undergraduate courses, and is the training that students now receive in the molecular life sciences appropriate to their future career paths?
Topics: Biochemistry; Computers; Humans; Molecular Biology; Teaching; Teaching Materials; Textbooks as Topic
PubMed: 11265252
DOI: 10.1038/35056600 -
Biochemistry and Molecular Biology... Jul 2019
Topics: Biochemistry; Humans; Interdisciplinary Studies; Molecular Biology
PubMed: 31246359
DOI: 10.1002/bmb.21283 -
Biochemistry Jun 2017
Topics: Biochemistry; Peer Review; Publishing
PubMed: 28605905
DOI: 10.1021/acs.biochem.7b00474 -
Journal of Medical Education Aug 1981
Topics: Biochemistry; Curriculum; Education, Medical
PubMed: 7265152
DOI: 10.1097/00001888-198108000-00014 -
Biochemistry and Molecular Biology... May 2019
Topics: Biochemistry; Humans; Laboratories; Molecular Biology
PubMed: 30737963
DOI: 10.1002/bmb.21217 -
Biochemistry Nov 2021The founding of the journal by the American Chemical Society 60 years ago was a highlight of the Society's growing commitment to chemically driven biochemistry. It was...
The founding of the journal by the American Chemical Society 60 years ago was a highlight of the Society's growing commitment to chemically driven biochemistry. It was a commitment that was nearly an additional 60 years in the making. In that time, biological chemistry was becoming more molecularly focused. Its relationship to the traditional chemical disciplines became apparent to a generation of young chemists, who grappled with defining the field's core chemical principles and creating new areas of research for a new journal. The path to was exciting, but it was also complex and difficult. Even its naming was arguable.
Topics: Biochemistry; History, 20th Century; History, 21st Century; Publishing; Terminology as Topic
PubMed: 34738805
DOI: 10.1021/acs.biochem.1c00569