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Current Opinion in Ophthalmology Mar 2022Biomechanics is an important aspect of the complex family of diseases known as the glaucomas. Here, we review recent studies of biomechanics in glaucoma. (Review)
Review
PURPOSE OF REVIEW
Biomechanics is an important aspect of the complex family of diseases known as the glaucomas. Here, we review recent studies of biomechanics in glaucoma.
RECENT FINDINGS
Several tissues have direct and/or indirect biomechanical roles in various forms of glaucoma, including the trabecular meshwork, cornea, peripapillary sclera, optic nerve head/sheath, and iris. Multiple mechanosensory mechanisms and signaling pathways continue to be identified in both the trabecular meshwork and optic nerve head. Further, the recent literature describes a variety of approaches for investigating the role of tissue biomechanics as a risk factor for glaucoma, including pathological stiffening of the trabecular meshwork, peripapillary scleral structural changes, and remodeling of the optic nerve head. Finally, there have been advances in incorporating biomechanical information in glaucoma prognoses, including corneal biomechanical parameters and iridial mechanical properties in angle-closure glaucoma.
SUMMARY
Biomechanics remains an active aspect of glaucoma research, with activity in both basic science and clinical translation. However, the role of biomechanics in glaucoma remains incompletely understood. Therefore, further studies are indicated to identify novel therapeutic approaches that leverage biomechanics. Importantly, clinical translation of appropriate assays of tissue biomechanical properties in glaucoma is also needed.
Topics: Biomechanical Phenomena; Glaucoma; Humans; Intraocular Pressure; Optic Disk; Sclera; Trabecular Meshwork
PubMed: 34954731
DOI: 10.1097/ICU.0000000000000829 -
Physical Medicine and Rehabilitation... Feb 2016Running biomechanics play an important role in the development of injuries. Performing a running biomechanics analysis on injured runners can help to develop treatment... (Review)
Review
Running biomechanics play an important role in the development of injuries. Performing a running biomechanics analysis on injured runners can help to develop treatment strategies. This article provides a framework for a systematic video-based running biomechanics analysis plan based on the current evidence on running injuries, using 2-dimensional (2D) video and readily available tools. Fourteen measurements are proposed in this analysis plan from lateral and posterior video. Identifying simple 2D surrogates for 3D biomechanic variables of interest allows for widespread translation of best practices, and have the best opportunity to impact the highly prevalent problem of the injured runner.
Topics: Athletic Injuries; Biomechanical Phenomena; Cumulative Trauma Disorders; Humans; Risk Factors; Running; Stress, Mechanical; Videotape Recording
PubMed: 26616185
DOI: 10.1016/j.pmr.2015.08.006 -
Journal of Musculoskeletal & Neuronal... Jun 2004Ligaments are specialized connective tissues with very interesting biomechanical properties. They have the ability to adapt to the complex functions that each are... (Review)
Review
Ligaments are specialized connective tissues with very interesting biomechanical properties. They have the ability to adapt to the complex functions that each are required to perform. While ligaments were once thought to be inert, they are in fact responsive to many local and systemic factors that influence their function within the organism. Injury to a ligament results in a drastic change in its structure and physiology and creates a situation where ligament function is restored by the formation of scar tissue that is biologically and biomechanically inferior to the tissue it replaces. This article will briefly review the basic structure, physiology and function of normal versus healing knee ligaments, referring specifically to what is known about two of the most extensively studied and clinically relevant knee ligaments, the anterior cruciate (ACL) and medial collateral (MCL) ligaments of the knee. Those readers wishing for more comprehensive sources of information on ligament biology and biomechanics are referred to many excellent reviews on these topics.
Topics: Biomechanical Phenomena; Humans; Ligaments; Wound Healing
PubMed: 15615126
DOI: No ID Found -
Acta Ortopedica Mexicana 2019The study of Biomechanics of the lumbar spine with clinical approach allows the physician related to locomotive sciences, to have a better interpretation of the clinical... (Review)
Review
The study of Biomechanics of the lumbar spine with clinical approach allows the physician related to locomotive sciences, to have a better interpretation of the clinical and radiological findings in order to carry out a treatment or a prediction of a medical problem with greater scientific foundation. The lumbar vertebral segment is studied from a biomechanical point of view in an integrated way, correlating with other body regions. The structures analyzed are the vertebrae, the intervertebral disks, the ligament and muscular system. The method of study goes from the static of the column to the dynamic, which includes the kinetic and kinematic aspects. The contradiction in the study of the lumbar spine is that the disorders of this body region are of the most frequent in the general and specialized medical consultation and, however, is not enough provided to the financial funds to carry out research.
Topics: Biomechanical Phenomena; Humans; Intervertebral Disc; Lumbar Vertebrae
PubMed: 32246612
DOI: No ID Found -
Physical Therapy Feb 2010A healthy gait pattern depends on an array of biomechanical features, orchestrated by the central nervous system for economy and stability. Injuries and other... (Review)
Review
A healthy gait pattern depends on an array of biomechanical features, orchestrated by the central nervous system for economy and stability. Injuries and other pathologies can alter these features and result in substantial gait deficits, often with detrimental consequences for energy expenditure and balance. An understanding of the role of biomechanics in the generation of healthy gait, therefore, can provide insight into these deficits. This article examines the basic principles of gait from the standpoint of dynamic walking, an approach that combines an inverted pendulum model of the stance leg with a pendulum model of the swing leg and its impact with the ground. The heel-strike at the end of each step has dynamic effects that can contribute to a periodic gait and its passive stability. Biomechanics, therefore, can account for much of the gait pattern, with additional motor inputs that are important for improving economy and stability. The dynamic walking approach can predict the consequences of disruptions to normal biomechanics, and the associated observations can help explain some aspects of impaired gait. This article reviews the basic principles of dynamic walking and the associated experimental evidence for healthy gait and then considers how the principles may be applied to clinical gait pathologies.
Topics: Biomechanical Phenomena; Gait; Humans; Kinesis; Models, Biological; Musculoskeletal Physiological Phenomena; Postural Balance; Posture; Walking
PubMed: 20023002
DOI: 10.2522/ptj.20090125 -
Knee Surgery, Sports Traumatology,... Apr 2017This article reviews the evidence for the roles of the anterolateral soft-tissue structures in rotatory stability of the knee, including their structural properties,... (Review)
Review
This article reviews the evidence for the roles of the anterolateral soft-tissue structures in rotatory stability of the knee, including their structural properties, isometry, and contributions to resisting tibial internal rotation. These data then lead to a biomechanical demonstration that the ilio-tibial band is the most important structure for the restraint of anterolateral rotatory instability. Level of evidence V.
Topics: Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Biomechanical Phenomena; Humans; Joint Deformities, Acquired; Joint Instability; Knee Joint; Ligaments, Articular; Rotation
PubMed: 28299387
DOI: 10.1007/s00167-017-4494-x -
Journal of Healthcare Engineering 2018
Topics: Animals; Bioengineering; Biomechanical Phenomena; Biomedical Engineering; Cardiac Rehabilitation; Humans; Orthopedic Procedures; Swine
PubMed: 30210751
DOI: 10.1155/2018/1716809 -
Knee Surgery, Sports Traumatology,... Dec 2021
Topics: Biomechanical Phenomena; Humans; Joint Instability; Musculoskeletal System; Shoulder; Shoulder Joint
PubMed: 34559246
DOI: 10.1007/s00167-021-06743-0 -
Journal of Strength and Conditioning... Jul 2012The purpose of this study was to compare the biomechanics of the traditional squat with 2 popular exercise variations commonly referred to as the powerlifting squat and... (Comparative Study)
Comparative Study
The purpose of this study was to compare the biomechanics of the traditional squat with 2 popular exercise variations commonly referred to as the powerlifting squat and box squat. Twelve male powerlifters performed the exercises with 30, 50, and 70% of their measured 1 repetition maximum (1RM), with instruction to lift the loads as fast as possible. Inverse dynamics and spatial tracking of the external resistance were used to quantify biomechanical variables. A range of significant kinematic and kinetic differences (p < 0.05) emerged between the exercises. The traditional squat was performed with a narrow stance, whereas the powerlifting squat and box squat were performed with similar wide stances (48.3 ± 3.8, 89.6 ± 4.9, 92.1 ± 5.1 cm, respectively). During the eccentric phase of the traditional squat, the knee traveled past the toes resulting in anterior displacement of the system center of mass (COM). In contrast, during the powerlifting squat and box squat, a more vertical shin position was maintained, resulting in posterior displacements of the system COM. These differences in linear displacements had a significant effect (p < 0.05) on a number of peak joint moments, with the greatest effects measured at the spine and ankle. For both joints, the largest peak moment was produced during the traditional squat, followed by the powerlifting squat, then box squat. Significant differences (p < 0.05) were also noted at the hip joint where the largest moment in all 3 planes were produced during the powerlifting squat. Coaches and athletes should be aware of the biomechanical differences between the squatting variations and select according to the kinematic and kinetic profile that best match the training goals.
Topics: Adult; Ankle; Biomechanical Phenomena; Hip; Humans; Knee; Male; Movement; Posture; Spine; Weight Lifting; Young Adult
PubMed: 22505136
DOI: 10.1519/JSC.0b013e3182577067 -
Journal of Comparative Physiology. A,... Mar 2023Representatives of arthropods, the largest animal phylum, occupy terrestrial, aquatic, arboreal, and subterranean niches. Their evolutionary success depends on specific...
Representatives of arthropods, the largest animal phylum, occupy terrestrial, aquatic, arboreal, and subterranean niches. Their evolutionary success depends on specific morphological and biomechanical adaptations related to their materials and structures. Biologists and engineers have become increasingly interested in exploring these natural solutions to understand relationships between structures, materials, and their functions in living organisms. The aim of this special issue is to present the state-of-the-art research in this interdisciplinary field using modern methodology, such as imaging techniques, mechanical testing, movement capture, and numerical modeling. It contains nine original research reports covering diverse topics, including flight, locomotion, and attachment of the arthropods. The research achievements are essential not only to understand ecological adaptations, and evolutionary and behavioral traits, but also to drive prominent advances for engineering from exploitation of numerous biomimetic ideas.
Topics: Animals; Arthropods; Biomechanical Phenomena; Locomotion; Biological Evolution; Acclimatization
PubMed: 36813948
DOI: 10.1007/s00359-023-01621-1