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Animals : An Open Access Journal From... Dec 2020The Sicilian black pig (SB) (Nero Siciliano), also known as the Nero dei Nebrodi, Nero delle Madonie, or Nero dell'Etna pig ecotype, is an autochthonous Italian breed.... (Review)
Review
The Sicilian black pig (SB) (Nero Siciliano), also known as the Nero dei Nebrodi, Nero delle Madonie, or Nero dell'Etna pig ecotype, is an autochthonous Italian breed. The origins of this breed date back to Greek and Carthaginian dominations. In ancient times, its breeding was fairly common throughout Sicily, registering only a temporary reduction during the Arab domination. This breed is known primarily for its distinctive black coat, although some individuals display wattles and a partially or wholly white face. The SB pig has a birth rate with an average per sow of 7.6 piglets, each of 1.4 kg live body weight, showing an average daily gain (ADG) of 346 g/day during the fattening period. Slaughter generally takes place at an average age of 390 days, with an average live weight of 95 kg. This breed also appears to withstand adverse climatic conditions and resist disease. The purpose of this manuscript is to offer a general overview regarding the Sicilian Black pig and to consider the recent findings related to genome investigation. The recent application of Next Generation Sequencing (NGS) technologies in the study of the genome of autochthonous breeds showed that polymorphisms of some candidate genes for production performance and phenotypic traits represent important information for selection processes. The protection of autochthonous breeds, intended as sources of genomic diversity for the further improvements of pigs for commercial use, constitutes a valuable opportunity to create new sustainable pig chains.
PubMed: 33297476
DOI: 10.3390/ani10122326 -
Philosophical Transactions of the Royal... Feb 2022Individuals occupying dominant and subordinate positions in social hierarchies exhibit divergent behaviours, physiology and neural functioning. Dominant animals express...
Individuals occupying dominant and subordinate positions in social hierarchies exhibit divergent behaviours, physiology and neural functioning. Dominant animals express higher levels of dominance behaviours such as aggression, territorial defence and mate-guarding. Dominants also signal their status via auditory, visual or chemical cues. Moreover, dominant animals typically increase reproductive behaviours and show enhanced spatial and social cognition as well as elevated arousal. These biobehavioural changes increase energetic demands that are met via shifting both energy intake and metabolism and are supported by coordinated changes in physiological systems including the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes as well as altered gene expression and sensitivity of neural circuits that regulate these behaviours. Conversely, subordinate animals inhibit dominance and often reproductive behaviours and exhibit physiological changes adapted to socially stressful contexts. Phenotypic changes in both dominant and subordinate individuals may be beneficial in the short-term but lead to long-term challenges to health. Further, rapid changes in social ranks occur as dominant animals socially ascend or descend and are associated with dynamic modulations in the brain and periphery. In this paper, we provide a broad overview of how behavioural and phenotypic changes associated with social dominance and subordination are expressed in neural and physiological plasticity. This article is part of the theme issue 'The centennial of the pecking order: current state and future prospects for the study of dominance hierarchies'.
Topics: Aggression; Animals; Hierarchy, Social; Reproduction; Social Dominance; Territoriality
PubMed: 35000436
DOI: 10.1098/rstb.2020.0443 -
PloS One 2020In many objective optimization problems (MaOPs), more than three distinct objectives are optimized. The challenging part in MaOPs is to get the Pareto approximation (PA)...
In many objective optimization problems (MaOPs), more than three distinct objectives are optimized. The challenging part in MaOPs is to get the Pareto approximation (PA) with high diversity and good convergence. In Literature, in order to solve the issue of diversity and convergence in MaOPs, many approaches are proposed using different multi objective evolutionary algorithms (MOEAs). Moreover, to get better results, the researchers use the sets of reference points to differentiate the solutions and to model the search process, it further evaluates and selects the non-dominating solutions by using the reference set of solutions. Furthermore, this technique is used in some of the swarm-based evolutionary algorithms. In this paper, we have used some effective adaptations of bat algorithm with the previous mentioned approach to effectively handle the many objective problems. Moreover, we have called this algorithm as many objective bat algorithm (MaOBAT). This algorithm is a biologically inspired algorithm, which uses echolocation power of micro bats. Each bat represents a complete solution, which can be evaluated based on the problem specific fitness function and then based on the dominance relationship, non-dominated solutions are selected. In proposed MaOBAT, dominance rank is used as dominance relationship (dominance rank of a solution means by how many other solutions a solution dominated). In our proposed strategy, dynamically allocated set of reference points are used, allowing the algorithm to have good convergence and high diversity pareto fronts (PF). The experimental results show that the proposed algorithm has significant advantages over several state-of-the-art algorithms in terms of the quality of the solution.
Topics: Computer Heuristics; Neural Networks, Computer
PubMed: 32525939
DOI: 10.1371/journal.pone.0234625 -
Cell Reports Oct 2023Healthy Kupffer cell (KC) pool is dominated by embryonic KCs (EmKCs), preserving liver homeostasis. How the KC pool varies upon injury remains unclear. Using chimeric...
Healthy Kupffer cell (KC) pool is dominated by embryonic KCs (EmKCs), preserving liver homeostasis. How the KC pool varies upon injury remains unclear. Using chimeric mice with bone marrow (BM) cells labeled with enhanced green fluorescent protein, we identify that BM monocyte-derived KCs (MoKCs) become dominant in cholestatic- or toxic-injured livers via immunofluorescence and mass cytometry. Single-cell RNA sequencing (scRNA-seq) unveils the enhanced proliferative, anti-apoptotic properties and repair potential of MoKCs compared with EmKCs, which are confirmed in vivo and ex vivo through flow cytometry, qPCR, Cell Counting Kit-8, and immunofluorescence. Furthermore, compared with EmKC-dominated livers, MoKC-dominated livers exhibit less functional damage, necrosis, and fibrosis under damage, as tested by serum alanine aminotransferase activity detection, H&E and Sirius red staining, qPCR, and western blot. Collectively, we highlight that MoKCs dominate the KC pool in injured livers and show enhanced proliferative and anti-apoptotic properties while also promoting repair and attenuating fibrosis.
Topics: Mice; Animals; Kupffer Cells; Monocytes; Liver; Necrosis; Fibrosis
PubMed: 37740916
DOI: 10.1016/j.celrep.2023.113164 -
Brain and Behavior May 2024Living in a social dominance hierarchy presents different benefits and challenges for dominant and subordinate males and females, which might in turn affect their...
BACKGROUND
Living in a social dominance hierarchy presents different benefits and challenges for dominant and subordinate males and females, which might in turn affect their cognitive needs. Despite the extensive research on social dominance in group-living species, there is still a knowledge gap regarding how social status impacts brain morphology and cognitive abilities.
METHODS
Here, we tested male and female dominants and subordinates of Neolamprologus pulcher, a social cichlid fish species with size-based hierarchy. We ran three executive cognitive function tests for cognitive flexibility (reversal learning test), self-control (detour test), and working memory (object permanence test), followed by brain and brain region size measurements.
RESULTS
Performance was not influenced by social status or sex. However, dominants exhibited a brain-body slope that was relatively steeper than that of subordinates. Furthermore, individual performance in reversal learning and detour tests correlated with brain morphology, with some trade-offs among major brain regions like telencephalon, cerebellum, and optic tectum.
CONCLUSION
As individuals' brain growth strategies varied depending on social status without affecting executive functions, the different associated challenges might yield a potential effect on social cognition instead. Overall, the findings highlight the importance of studying the individual and not just species to understand better how the individual's ecology might shape its brain and cognition.
Topics: Animals; Cichlids; Female; Male; Executive Function; Brain; Social Dominance; Reversal Learning; Memory, Short-Term
PubMed: 38680075
DOI: 10.1002/brb3.3484 -
International Journal of Environmental... Nov 2022Monodominant (one species dominates) or polidominant (multiple species dominate) cyanobacterial blooms are pronounced in productive freshwater ecosystems and pose a...
Monodominant (one species dominates) or polidominant (multiple species dominate) cyanobacterial blooms are pronounced in productive freshwater ecosystems and pose a potential threat to the biota due to the synthesis of toxins. Seasonal changes in cyanobacteria species and cyanometabolites composition were studied in two shallow temperate eutrophic lakes. Data on cyanobacteria biomass and diversity of dominant species in the lakes were combined with chemical and molecular analyses of fifteen potentially toxin-producing cyanobacteria species (248 isolates from the lakes). Anatoxin-a, saxitoxin, microcystins and other non-ribosomal peptides formed the diverse profiles in monodominant () and polidominant (, spp. and ) lakes. However, the harmfulness of the blooms depended on the ability of the dominant species to synthesize cyanometabolites. It was confirmed that . produced a greater amount and diverse range of MCs and other NRPs. In the polidominant lake, isolates of the co-dominant . , . and . synthesized no or only small amounts of cyanometabolites. In general, the profile of cyanometabolites was greater in cyanobacteria isolates than in environmental samples, indicating a high potential for toxic cyanobacteria bloom.
Topics: Lakes; Ecosystem; Cyanobacteria; Biota; Biomass
PubMed: 36430059
DOI: 10.3390/ijerph192215341 -
Animal Behaviour Mar 2012In cooperatively breeding animals, in which nonbreeding subordinates assist in rearing offspring born to dominants, breeders and helpers may be in conflict over their...
In cooperatively breeding animals, in which nonbreeding subordinates assist in rearing offspring born to dominants, breeders and helpers may be in conflict over their respective contributions to offspring care and selection may favour breeders that use aggression to elevate the work rates of helpers. We tested the prediction that dominant female meerkats, Suricata suricatta, should increase aggression towards subordinates when the need for help is higher, by playing back recordings of pup begging calls to simulate increased need for help. Second, we tested the prediction that dominants should reduce aggression when subordinates help more, by playing back recordings of feeding calls to simulate elevated pup provisioning rates by subordinates. Neither of the two playback experiments affected rates of aggressive interactions between breeding females and helpers. Instead, breeding females increased their own level of pup provisioning in response to increased pup begging. Hence, our results do not support a role of aggression in regulating helping behaviour in meerkats, but suggest that pup provisioning can be explained by direct and/or indirect benefits derived from helping. As yet, firm evidence that breeders use aggression to promote helping by subordinates in cooperative animal societies remains elusive.
PubMed: 22505769
DOI: 10.1016/j.anbehav.2011.12.032 -
Cytotechnology Apr 2007As medicine moves into the 21st century, life saving therapies will move from inception into medical products faster if there is a better synergy between science and...
As medicine moves into the 21st century, life saving therapies will move from inception into medical products faster if there is a better synergy between science and business. Medicine appears to have 50-year innovative cycles of education and scientific discoveries. In the 1880's, the chemical industry in Germany was faced with the dilemma of modernization to exploit the new scientific discoveries. The solution was the spawning of novel technical colleges for training in these new chemical industries. The impact of those new employees and their groundbreaking compounds had a profound influence on medicine and medical education in Germany between 1880 and 1930. Germany dominated international science during this period and was a training center for scientists worldwide. This model of synergy between education and business was envied and admired in Europe, Asia and America. British science soon after evolved to dominate the field of science during the prewar and post World War (1930's-1970's) because the German scientists fled Hitler's government. These expatriated scientists had a profound influence on the teaching and training of British scientists, which lead to advances in medicine such as antibiotics. After the Second World War, the US government wisely funded the development of the medical infrastructure that we see today. British and German scientists in medicine moved to America because of this bountiful funding for their research. These expatriated scientists helped drive these medical advances into commercialized products by the 1980's. America has been the center of medical education and advances of biotechnology but will it continue? International scientists trained in America have started to return to Europe and Asia. These American-trained scientists and their governments are very aware of the commercial potential of biotechnology. Those governments are now more prepared to play an active role this new science. Germany, Ireland, Britain, Singapore, Taiwan and Israel are such examples of this government support for biotechnology in the 21st century. Will the US continue to maintain its domination of biotechnology in this century? Will the US education system adjust to the new dynamic of synergistic relationships between the education system, industry and government? This article will try to address these questions but also will help the reader understand who will emerge by 2015 as the leader in science and education.
PubMed: 19003196
DOI: 10.1007/s10616-007-9056-5 -
International Journal of Sports... 2022The Lower Quarter Y-Balance Test (YBT-LQ) has been shown to be reliable for assessing dynamic balance in children and adolescents. However, limited research is available...
BACKGROUND
The Lower Quarter Y-Balance Test (YBT-LQ) has been shown to be reliable for assessing dynamic balance in children and adolescents. However, limited research is available about the effects of leg dominance on YBT-LQ performance in adolescents. In addition, there is no consensus on the use of maximum reach or mean reach distance being a better measure of YBT-LQ performance.
HYPOTHESIS/PURPOSE
The purposes of this study were to determine if there is a difference in the YBT-LQ performance between the dominant and non-dominant limbs in non-athlete adolescents, and to compare the reliability of the maximum reach scores to that of the mean reach scores in this population.
STUDY DESIGN
Prospective cohort study.
METHODS
Twenty-six healthy non-athlete adolescents (13.6 ± 1.0 years, 22 girls, 4 boys) performed the YBT-LQ on two separate days while the same investigator scored their performance. Paired -tests were used to compare reach distances on dominant and non-dominate stance limbs. Intraclass correlation coefficients (ICC) were calculated for the maximum and mean reach distances for three directions (anterior, posterolateral, posteromedial) and the composite scores on each limb.
RESULTS
There was no significant difference in YBT-LQ performance between dominant and non-dominant stance limbs ( > 0.05). Overall, the between-day intra-rater reliability for maximum reach and mean reach scores was moderate-to-good for both limbs (ICC = 0.59 - 0.83), but was poor for the composite score on the dominant limb (ICC = 0.42) and maximum anterior reach on non-dominant limb (ICC = 0.48).
CONCLUSION
Limb dominance does not seem to be a factor for YBT-LQ performance in this population. The YBT-LQ appears to be a reliable tool for dynamic balance assessment in non-athlete adolescents using the individual score of each direction. The use of mean reach measures seems to slightly improve reliability, specifically the anterior reach direction, in this population.
LEVEL OF EVIDENCE
Level 2b.
PubMed: 35136685
DOI: 10.26603/001c.30996 -
Srpski Arhiv Za Celokupno Lekarstvo 2010Hand dominance is defined as a proneness to use one hand rather than another in performing the majority of activities and this is the most obvious example of cerebral... (Review)
Review
Hand dominance is defined as a proneness to use one hand rather than another in performing the majority of activities and this is the most obvious example of cerebral lateralization and an exclusive human characteristic. Left-handed people comprise 6-14% of the total population, while in Serbia, this percentage is 5-10%, moving from undeveloped to developed environments, where a socio-cultural pressure is less present. There is no agreement between investigators who in fact may be considered a left-handed person, about the percentage of left-handers in the population and about the etiology of left-handedness. In the scientific literature left-handedness has been related to health disorders (spine deformities, immunological disorders, migraine, neurosis, depressive psychosis, schizophrenia, insomnia, homosexuality, diabetes mellitus, arterial hypertension, sleep apnea, enuresis nocturna and Down Syndrome), developmental disorders (autism, dislexia and sttutering) and traumatism. The most reliable scientific evidences have been published about the relationship between left-handedness and spinal deformities in school children in puberty and with traumatism in general population. The controversy of other results in up-to-now investigations of health aspects of left-handedness may partly be explained by a scientific disagreement whether writing with the left hand is a sufficient criterium for left-handedness, or is it necessary to investigate other parameters for laterality assessment. Explanation of health aspects of left-handedness is dominantly based on Geschwind-Galaburda model about "anomalous" cerebral domination, as a consequence of hormonal disbalance.
Topics: Dominance, Cerebral; Functional Laterality; Health Status; Humans
PubMed: 20607990
DOI: 10.2298/sarh1006387m