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Psychiatria Polska Jun 2022To assess attachment styles among adolescents (13-16 years) with ADHD or ADHD and oppositional defiant disorders (ODD).
OBJECTIVES
To assess attachment styles among adolescents (13-16 years) with ADHD or ADHD and oppositional defiant disorders (ODD).
METHODS
The Parents and Peers Attachment (IPPA) and the Parent Bonding Questionnaire (PBI) were used in three groups of teenagers raised in biological families: (1) ADHD/ODD group (n = 40), (2) ADHD group (n = 40) and (3) K (control) group of teenagers (n = 40) who have not benefited from psychological or psychiatric care in the past or at present.
RESULTS
Parental attachment styles in the area of "Trust", "Communication" and "Alienation" (IPPA), and "Care" and "Control" (PBI) in the ADHD/ODD group differ significantly compared to the control group. Teens from the ADHD/ODD group report to have experienced significantly less "Trust" and "Communication" (IPPA), and "Care" (PBI) in relationships with parents and more "Alienation" (IPPA) and "Control" (PBI) than adolescents in the ADHD group. Attachment patterns with peers in both clinical and control groups differ significantly. The ADHD/ODD group is dominated by the anxious-avoidant style of attachment to the mother and father, in the ADHD group, a secure style in relation to the mother and anxious-avoidant in relation to the father. In relations with peers in the ADHD/ODD group and the ADHD group, the anxious-avoidant style dominates.
CONCLUSIONS
The attachment style is significantly different in adolescents diagnosed with ADHD and ODD than in adolescents with only ADHD. In the ADHD/ODD group and the ADHD group, unlike in the group of adolescents without a psychiatric diagnosis, insecure attachment styles for parents and peers dominate (mainly anxious-avoidant style).
Topics: Adolescent; Humans; Attention Deficit Disorder with Hyperactivity; Attention Deficit and Disruptive Behavior Disorders; Parents
PubMed: 36342984
DOI: 10.12740/PP/OnlineFirst/130366 -
Brain levels of arginine-vasotocin and isotocin in dominant and subordinate males of a cichlid fish.Hormones and Behavior Feb 2012The nonapeptides arginine-vasotocin (AVT) and isotocin (IT), which are the teleost homologues of arginine-vasopressin and oxytocin in mammals, have well established... (Comparative Study)
Comparative Study
The nonapeptides arginine-vasotocin (AVT) and isotocin (IT), which are the teleost homologues of arginine-vasopressin and oxytocin in mammals, have well established peripheral effects on osmoregulation and stress response, and central effects on social behavior. However, all studies that have looked so far into the relationship between these nonapeptides and social behavior have used indirect measures of AVT/IT activity (i.e. immunohistochemistry of AVT/IT immunoreactive neurons, or AVT/IT or their receptors mRNA expression with in situ hybridization or qPCR) and therefore direct measures of peptide levels in relation to social behavior are still lacking. Here we use a recently developed high-performance liquid chromatography analysis with fluorescence detection (HPLC-FL) method to quantify the levels of both AVT and IT in macro-dissected brain areas [i.e. olfactory bulbs, telencephalon, diencephalon, optic tectum, cerebellum, and hindbrain (= rhombencephalon minus cerebellum)] and pituitary of dominant and subordinate male cichlid fish (Oreochromis mossambicus). The pituitary shows higher levels of both peptides than any of the brain macroareas, and the olfactory bulbs have the highest AVT among all brain areas. Except for IT in the telencephalon there is a lack of correlations between central levels and pituitary peptide levels, suggesting an independent control of hypophysial and CNS nonapeptide secretion. There were also no correlations between AVT and IT levels either for each brain region or for the pituitary gland, suggesting a decoupled activity of the AVT and IT systems at the CNS level. Subordinate AVT pituitary levels are significantly higher than those of dominants, and dominant hindbrain IT levels are significantly higher than those of subordinates, suggesting a potential involvement of AVT in social stress in subordinate fish and of IT in the regulation of dominant behavior at the level of the hindbrain. Since in this species dominant males use urine to communicate social status and since AVT is known to have an antidiuretic effect, we have also investigated the effect of social status on urine storage. As predicted, dominant males stored significantly more urine than subordinates. Given these results we suggest that AVT/IT play a key role in orchestrating social phenotypes, acting both as central neuromodulators that promote behavioral plasticity and as peripheral hormones that promote integrated physiological changes.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Cichlids; Dominance-Subordination; Hydrocortisone; Male; Oxytocin; Pituitary Gland; Stress, Psychological; Urine; Vasotocin
PubMed: 22206822
DOI: 10.1016/j.yhbeh.2011.12.008 -
Current Biology : CB Aug 2022Animals often display prosocial behaviors, performing actions that benefit others. Although prosociality is essential for social bonding and cooperation, we still know...
Animals often display prosocial behaviors, performing actions that benefit others. Although prosociality is essential for social bonding and cooperation, we still know little about how animals integrate behavioral cues from those in need to make decisions that increase their well-being. To address this question, we used a two-choice task where rats can provide rewards to a conspecific in the absence of self-benefit and investigated which conditions promote prosociality by manipulating the social context of the interacting animals. Although sex or degree of familiarity did not affect prosocial choices in rats, social hierarchy revealed to be a potent modulator, with dominant decision-makers showing faster emergence and higher levels of prosocial choices toward their submissive cage mates. Leveraging quantitative analysis of multimodal social dynamics prior to choice, we identified that pairs with dominant decision-makers exhibited more proximal interactions. Interestingly, these closer interactions were driven by submissive animals that modulated their position and movement following their dominants and whose 50-kHz vocalization rate correlated with dominants' prosociality. Moreover, Granger causality revealed stronger bidirectional influences in pairs with dominant focals and submissive recipients, indicating increased behavioral coordination. Finally, multivariate analysis highlighted body language as the main information dominants use on a trial-by-trial basis to learn that their actions have effects on others. Our results provide a refined understanding of the behavioral dynamics that rats use for action-selection upon perception of socially relevant cues and navigate social decision-making.
Topics: Altruism; Animals; Cues; Hierarchy, Social; Rats; Reward; Social Behavior
PubMed: 35803272
DOI: 10.1016/j.cub.2022.06.026 -
Frontiers in Microbiology 2022Due to global warming, shorter ice cover duration might drastically affect the ecology of lakes currently undergoing seasonal surface freezing. High-mountain lakes show...
Due to global warming, shorter ice cover duration might drastically affect the ecology of lakes currently undergoing seasonal surface freezing. High-mountain lakes show snow-rich ice covers that determine contrasting conditions between ice-off and ice-on periods. We characterized the bacterioplankton seasonality in a deep high-mountain lake ice-covered for half a year. The lake shows a rich core bacterioplankton community consisting of three components: (i) an assemblage stable throughout the year, dominated by Actinobacteria, resistant to all environmental conditions; (ii) an ice-on-resilient assemblage dominating during the ice-covered period, which is more diverse than the other components and includes a high abundance of Verrucomicrobia; the deep hypolimnion constitutes a refuge for many of the typical under-ice taxa, many of which recover quickly during autumn mixing; and (iii) an ice-off-resilient assemblage, which members peak in summer in epilimnetic waters when the rest decline, characterized by a dominance of , and . The rich core community and low random elements compared to other relatively small cold lakes can be attributed to its simple hydrological network in a poorly-vegetated catchment, the long water-residence time ( 4 years), and the long ice-cover duration; features common to many headwater deep high-mountain lakes.
PubMed: 36187988
DOI: 10.3389/fmicb.2022.935378 -
The New Phytologist Oct 2019A crucial step in the transition from outcrossing to self-fertilization is the loss of genetic self-incompatibility (SI). In the Brassicaceae, SI involves the...
A crucial step in the transition from outcrossing to self-fertilization is the loss of genetic self-incompatibility (SI). In the Brassicaceae, SI involves the interaction of female and male specificity components, encoded by the genes SRK and SCR at the self-incompatibility locus (S-locus). Theory predicts that S-linked mutations, and especially dominant mutations in SCR, are likely to contribute to loss of SI. However, few studies have investigated the contribution of dominant mutations to loss of SI in wild plant species. Here, we investigate the genetic basis of loss of SI in the self-fertilizing crucifer species Capsella orientalis, by combining genetic mapping, long-read sequencing of complete S-haplotypes, gene expression analyses and controlled crosses. We show that loss of SI in C. orientalis occurred < 2.6 Mya and maps as a dominant trait to the S-locus. We identify a fixed frameshift deletion in the male specificity gene SCR and confirm loss of male SI specificity. We further identify an S-linked small RNA that is predicted to cause dominance of self-compatibility. Our results agree with predictions on the contribution of dominant S-linked mutations to loss of SI, and thus provide new insights into the molecular basis of mating system transitions.
Topics: Base Sequence; Capsella; Crosses, Genetic; Frameshift Mutation; Gene Expression Regulation, Plant; Genes, Dominant; Genetic Loci; Haplotypes; Phylogeny; Quantitative Trait, Heritable; RNA, Plant; Reproduction; Self-Incompatibility in Flowering Plants; Time Factors
PubMed: 31254395
DOI: 10.1111/nph.16035 -
Scientific Reports Mar 2022When our eyes are confronted with discrepant images (yielding incompatible retinal inputs) interocular competition (IOC) is instigated. During IOC, one image temporarily...
When our eyes are confronted with discrepant images (yielding incompatible retinal inputs) interocular competition (IOC) is instigated. During IOC, one image temporarily dominates perception, while the other is suppressed. Many factors affecting IOC have been extensively examined. One factor that received surprisingly little attention, however, is the stimulus' visual hemifield (VHF) of origin. This is remarkable, as the VHF location of stimuli is known to affect visual performance in various contexts. Prompted by exploratory analyses, we examined five independent datasets of breaking continuous flash suppression experiments, to establish the VHF's role in IOC. We found that targets presented in nasal VHF locations broke through suppression much faster than targets in temporal VHF locations. Furthermore, we found that the magnitude of this nasal advantage depended on how strongly the targets were suppressed: the nasal advantage was larger for the recessive eye than for the dominant eye, and was larger in observers with a greater dominance imbalance between the eyes. Our findings suggest that the nasal advantage reported here originates in processing stages where IOC is resolved. Finally, we propose that a nasal advantage in IOC serves an adaptive role in human vision, as it can aid perception of partially occluded objects.
Topics: Attention; Humans; Photic Stimulation; Retina; Vision, Binocular; Visual Fields; Visual Perception
PubMed: 35301373
DOI: 10.1038/s41598-022-08473-w -
Ecology Letters Jan 2024Dominance of neotropical tree communities by a few species is widely documented, but dominant trees show a variety of distributional patterns still poorly understood....
Dominance of neotropical tree communities by a few species is widely documented, but dominant trees show a variety of distributional patterns still poorly understood. Here, we used 503 forest inventory plots (93,719 individuals ≥2.5 cm diameter, 2609 species) to explore the relationships between local abundance, regional frequency and spatial aggregation of dominant species in four main habitat types in western Amazonia. Although the abundance-occupancy relationship is positive for the full dataset, we found that among dominant Amazonian tree species, there is a strong negative relationship between local abundance and regional frequency and/or spatial aggregation across habitat types. Our findings suggest an ecological trade-off whereby dominant species can be locally abundant (local dominants) or regionally widespread (widespread dominants), but rarely both (oligarchs). Given the importance of dominant species as drivers of diversity and ecosystem functioning, unravelling different dominance patterns is a research priority to direct conservation efforts in Amazonian forests.
Topics: Humans; Ecosystem; Forests; Trees; Brazil; Biodiversity
PubMed: 38111128
DOI: 10.1111/ele.14351 -
Frontiers in Behavioral Neuroscience 2021Social status-dependent modulation of neural circuits has been investigated extensively in vertebrate and invertebrate systems. However, the effects of social status on...
Social status-dependent modulation of neural circuits has been investigated extensively in vertebrate and invertebrate systems. However, the effects of social status on neuromodulatory systems that drive motor activity are poorly understood. Zebrafish form a stable social relationship that consists of socially dominant and subordinate animals. The locomotor behavior patterns differ according to their social ranks. The sensitivity of the Mauthner startle escape response in subordinates increases compared to dominants while dominants increase their swimming frequency compared to subordinates. Here, we investigated the role of the endocannabinoid system (ECS) in mediating these differences in motor activities. We show that brain gene expression of key ECS protein pathways are socially regulated. Diacylglycerol lipase (DAGL) expression significantly increased in dominants and significantly decreased in subordinates relative to controls. Moreover, brain gene expression of the cannabinoid 1 receptor (CBR) was significantly increased in subordinates relative to controls. Secondly, increasing ECS activity with JZL184 reversed swimming activity patterns in dominant and subordinate animals. JZL184 did not affect the sensitivity of the startle escape response in dominants while it was significantly reduced in subordinates. Thirdly, blockage of CBR function with AM-251 had no effect on dominants startle escape response sensitivity, but startle sensitivity was significantly reduced in subordinates. Additionally, AM-251 did not affect swimming activities in either social phenotypes. Fourthly, we demonstrate that the effects of ECS modulation of the startle escape circuit is mediated via the dopaminergic system specifically via the dopamine D1 receptor. Finally, our empirical results complemented with neurocomputational modeling suggest that social status influences the ECS to regulate the balance in synaptic strength between excitatory and inhibitory inputs to control the excitability of motor behaviors. Collectively, this study provides new insights of how social factors impact nervous system function to reconfigure the synergistic interactions of neuromodulatory pathways to optimize motor output.
PubMed: 34045945
DOI: 10.3389/fnbeh.2021.668589 -
Nucleic Acids Research Jan 2020IRF3, IRF5 and IRF9 are transcription factors, which play distinct roles in the regulation of antiviral and inflammatory responses. The determinants that mediate...
Specific enhancer selection by IRF3, IRF5 and IRF9 is determined by ISRE half-sites, 5' and 3' flanking bases, collaborating transcription factors and the chromatin environment in a combinatorial fashion.
IRF3, IRF5 and IRF9 are transcription factors, which play distinct roles in the regulation of antiviral and inflammatory responses. The determinants that mediate IRF-specific enhancer selection are not fully understood. To uncover regions occupied predominantly by IRF3, IRF5 or IRF9, we performed ChIP-seq experiments in activated murine dendritic cells. The identified regions were analysed with respect to the enrichment of DNA motifs, the interferon-stimulated response element (ISRE) and ISRE half-site variants, and chromatin accessibility. Using a machine learning method, we investigated the predictability of IRF-dominance. We found that IRF5-dominant regions differed fundamentally from the IRF3- and IRF9-dominant regions: ISREs were rare, while the NFKB motif and special ISRE half-sites, such as 5'-GAGA-3' and 5'-GACA-3', were enriched. IRF3- and IRF9-dominant regions were characterized by the enriched ISRE motif and lower frequency of accessible chromatin. Enrichment analysis and the machine learning method uncovered the features that favour IRF3 or IRF9 dominancy (e.g. a tripartite form of ISRE and motifs for NF-κB for IRF3, and the GAS motif and certain ISRE variants for IRF9). This study contributes to our understanding of how IRF members, which bind overlapping sets of DNA sequences, can initiate signal-dependent responses without activating superfluous or harmful programmes.
Topics: Animals; Cell Line; Chromatin; Dendritic Cells; Enhancer Elements, Genetic; Gene Expression Regulation; Humans; Interferon Regulatory Factor-3; Interferon Regulatory Factors; Interferon-Stimulated Gene Factor 3, gamma Subunit; Machine Learning; Mice; NF-kappa B; Nucleotide Motifs; Principal Component Analysis; Response Elements; Transcription Factors
PubMed: 31799619
DOI: 10.1093/nar/gkz1112 -
Heliyon Sep 2020acts as an important ecological filters in dominated communities. A study to investigate the effects of its dominance in the vegetation of Nyungwe was conducted....
acts as an important ecological filters in dominated communities. A study to investigate the effects of its dominance in the vegetation of Nyungwe was conducted. Sampling was done in Mubuga and Uwajerome mountains. A total of 53 alternate plots measuring 10 m × 10 m were sampled along a transect at regular interval of 10 m. In each plot, the species were identified and the cover abundance measured subjectively. Plant strategies, succession, biological forms, distribution and conservation status of each species were also determined. Data on species composition and cover abundance were analyzed using MVSP software and Shannon -Weiner index was used to determine diversity of communities. Descriptive statistics were used to assess the characteristics of the species. A total of 141 species belonging to 100 genera and 54 families and distributed in four plant communities were identified. were dominant in communities I, II and III, with average cover of 31%, 6% and 4% respectively. The primary forest was dominated by and in community IV, with 21% and 10% coverage respectively. Shannon- Weiner and evenness indices were 1.538, 2.925, 3.251 and 2.940 and 0.436, 0.716, 0.791 and 0.768 in communities I, II, III and IV respectively. Species richness were 34, 36, 61 and 46 in communities I, II, III and IV respectively. Ruderal, chamaephytes, secondary, Africa tropical and least concerns plant species predominated in vegetation areas with 76% 48%, 69%, 43% and 90% of total species respectively. Competitive, phanerophytes, primary, Afromontane and least concerns plant species dominated in non-dominated area with 54%, 52%, 58%, 40% and 88% of total species respectively. restricted the growth of trees as exhibited by the presence of few phanerophytes and enhanced the growth of ruderal species, both of which are indicators of disturbed forest. The tree species observed in cut-areas was .
PubMed: 32944668
DOI: 10.1016/j.heliyon.2020.e04806