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BMC Medical Imaging Mar 2023Lumbago is a global disease that affects more than 500 million people worldwide. Bone marrow oedema is one of the main causes of the condition and clinical diagnosis is...
BACKGROUND
Lumbago is a global disease that affects more than 500 million people worldwide. Bone marrow oedema is one of the main causes of the condition and clinical diagnosis is mainly made by radiologists manually reviewing MRI images to determine whether oedema is present. However, the number of patients with Lumbago has risen dramatically in recent years, which has brought a huge workload to radiologists. In order to improve the efficiency of diagnosis, this paper is devoted to developing and evaluating a neural network for detecting bone marrow edema in MRI images.
RELATED WORK
Inspired by the development of deep learning and image processing techniques, we design a deep learning detection algorithm specifically for the detection of bone marrow oedema from lumbar MRI images. We introduce deformable convolution, feature pyramid networks and neural architecture search modules, and redesign the existing neural networks. We explain in detail the construction of the network and illustrate the setting of the network hyperparameters.
RESULTS AND DISCUSSION
The detection accuracy of our algorithm is excellent. And its accuracy of detecting bone marrow oedema reached up to 90.6[Formula: see text], an improvement of 5.7[Formula: see text] compared to the original. The recall of our neural network is 95.1[Formula: see text], and the F1-measure also reaches 92.8[Formula: see text]. And our algorithm is fast in detecting it, taking only 0.144 s per image.
CONCLUSION
Extensive experiments have demonstrated that deformable convolution and aggregated feature pyramid structures are conducive for the detection of bone marrow oedema. Our algorithm has better detection accuracy and good detection speed compared to other algorithms.
Topics: Humans; Bone Marrow; Low Back Pain; Neural Networks, Computer; Algorithms; Edema
PubMed: 36978011
DOI: 10.1186/s12880-023-01003-8 -
British Medical Journal Jul 1979
Topics: Adult; Edema; Humans; Insulin; Male
PubMed: 466342
DOI: 10.1136/bmj.2.6183.177-a -
BMC Musculoskeletal Disorders Aug 2023The peripatellar fat pads are critical for protective cushioning during movement, and their endocrine function has been shown to affect osteoarthritis. Magnetic...
BACKGROUND
The peripatellar fat pads are critical for protective cushioning during movement, and their endocrine function has been shown to affect osteoarthritis. Magnetic resonance imaging (MRI) is frequently used to visualize edema of the peripatellar fat pads due to injury. In this study, we aimed to assess the relationship between peripatellar fat pad edema and patellofemoral maltracking MRI parameters and investigate the association among cases of peripatellar fat pad edema.
METHODS
Age- and sex-matched peripatellar fat pad edema cases were identified and divided into superolateral Hoffa, quadriceps, and prefemoral groups. Images were assessed according to tibial tuberosity lateralization, trochlear dysplasia, patellar alta, patellar tilt, and bisect offset. McNemar's test or paired t-tests and Spearman's correlation were used for statistical analysis. Interobserver agreement was assessed with the intraclass correlation coefficient.
RESULTS
Of 1210 MRI scans, 50, 68, and 42 cases were in the superolateral Hoffa, quadriceps, and prefemoral groups, respectively. Subjects with superolateral Hoffa fat pad edema had a lower lateral trochlear inclination (p = 0.028), higher Insall-Salvati (p < 0.001) and modified Insall-Salvati (p = 0.021) ratios, and lower patellotrochlear index (p < 0.001) than controls. The prefemoral group had a lower lateral trochlear inclination (p = 0.014) and higher Insall-Salvati (p < 0.001) and modified Insall-Salvati (p = 0.004) ratios compared with the control group. In contrast, the patellotrochlear index (p = 0.001) was lower. Mean patellar tilt angle (p = 0.019) and mean bisect offset (p = 0.005) were significantly different between cases and controls. The quadriceps group showed no association. Superolateral Hoffa was positively correlated with prefemoral (p < 0.001, r = 0.408) and negatively correlated with quadriceps (p < 0.001, r = -0.500) fat pad edema.
CONCLUSIONS
Superolateral Hoffa and prefemoral fat pad edemas were associated with patellar maltracking parameters. Quadriceps fat pad edema and maltracking parameters were not associated. Superolateral Hoffa fat pad edema was positively correlated with prefemoral and negatively correlated with quadriceps fat pad edema.
Topics: Humans; Joint Diseases; Adipose Tissue; Bone Diseases; Case-Control Studies; Edema; Magnetic Resonance Imaging
PubMed: 37626375
DOI: 10.1186/s12891-023-06827-7 -
Archives of Disease in Childhood.... Dec 2021A 14-year-old girl was admitted to our institute with a history of intermittent bilateral ankle swelling, and moderate but progressively worsening pain which has lasted...
A 14-year-old girl was admitted to our institute with a history of intermittent bilateral ankle swelling, and moderate but progressively worsening pain which has lasted for 2 years.The patient's history was unremarkable. She did not take medications and was not involved in any sports activity. She reported no fever, gastrointestinal symptoms, fatigue, weight loss, travels abroad or previous infections. She reported moderate pain at night, associated with a sense of heaviness, tightness and general discomfort, and with no response to ibuprofen.Physical examination was remarkable only for bilateral ankle non-pitting oedema, more evident on the left leg, with a thickened skinfold at the base of the second toe, and without redness, swelling or skin warming.The patient had been previously examined, and her foot and ankle X-rays, ultrasound (US) and MRI were all negative. Blood tests (white cell count, C reactive protein, erythrocyte sedimentation rate, albumin, antinuclear antibodies, creatinine, transaminase, creatine kinase, lactate dehydrogenase, thyroid function and glucose) and urinalysis were in the normal range. Her ocular assessment and echocardiogram were also normal.
Topics: Adolescent; Ankle; Edema; Female; Humans; Magnetic Resonance Imaging; Neoplasms; Ultrasonography
PubMed: 32122955
DOI: 10.1136/archdischild-2019-318096 -
Annales de Biologie Clinique Dec 2018The Waldmann's disease is a primitive intestinal lymphangectasia. This exsudative enteropathy initiates a protein leakage by the digestive tract. Clinically, this...
The Waldmann's disease is a primitive intestinal lymphangectasia. This exsudative enteropathy initiates a protein leakage by the digestive tract. Clinically, this syndrome is characterised by oedemas and biologically by hypoprotidemia and loss of lymphocytes T CD4+, which increases a risk for infections. Here, we describe a patient's case for whom the protein loss was aggravated by a nephrotic syndrome.
Topics: Child; Child, Preschool; Edema; Female; Follow-Up Studies; Humans; Infant; Lymphangiectasis, Intestinal; Lymphedema
PubMed: 30543193
DOI: 10.1684/abc.2018.1398 -
The Western Journal of Emergency... Jul 2014
Topics: Conjunctival Diseases; Edema; Eye Injuries; Humans; Male; Middle Aged
PubMed: 25035727
DOI: 10.5811/westjem.2014.3.21550 -
Diagnostic Pathology Feb 2016Massive ovarian oedema is a rare non-neoplastic clinicopathologic entity has a higher incidence in women during their second and third life decade. The oedema can be... (Review)
Review
BACKGROUND
Massive ovarian oedema is a rare non-neoplastic clinicopathologic entity has a higher incidence in women during their second and third life decade. The oedema can be presented in one or both ovaries as a result of partial intermittent torsion of the ovarian pedicle that interferes to the venal and lymphatic drainage of the ovary.
CASE PRESENTATION
We present a clinical case of a 16 year old with massive ovarian oedema and we performed a review of the literature. The pathophysiology of this entity is very complex. We tried to perform a complete review of the literature and focus on the complexity of this entity as far as its pathophysiological backround is concerned and as far as its clinical presentation is concerned.
CONCLUSIONS
In conclusion, massive ovarian oedema is a rare, multi disease mimicking clinical entity, with an acute or progressive clinical presentation. It has also to be a part of our differential diagnosis in cases of acute abdominal pain and we have to try to treat her conservatively, in order to preserve fertility.
Topics: Adolescent; Biopsy; Diagnosis, Differential; Edema; Female; Humans; Ovarian Diseases; Predictive Value of Tests; Tomography, X-Ray Computed
PubMed: 26843454
DOI: 10.1186/s13000-016-0469-3 -
International Journal of Hyperthermia :... 2022Investigate the relationships between endopelvic fascial edema and its influencing factors after ultrasound-guided high-intensity focused ultrasound (USgHIFU) ablation...
OBJECTIVE
Investigate the relationships between endopelvic fascial edema and its influencing factors after ultrasound-guided high-intensity focused ultrasound (USgHIFU) ablation of uterine fibroids.
METHODS
This retrospective study included 688 women with uterine fibroids treated by USgHIFU; based on post-treatment MRI, the patients were divided into two groups: endopelvic fascial edema group and nonedema group. The specific location of fascial edema of each patient was also recorded. Fascial edema and fibroid features and treatment parameters were set as the dependent and independent variables, respectively, and the correlations were studied using univariate and multivariate analyses. The relationship between the pain-related adverse events and location of fascial edema was analyzed by χ and fisher's exact tests.
RESULTS
Edema and nonedema groups had 556 and 112 patients, respectively. Among the edema patients, posterior fascial edema incidence was the highest. Multifactorial analysis showed that the energy efficiency factor (EEF), fibroid location, and enhancement type were positively associated with endopelvic fascial edema ( < 0.05), while the distance from dorsal surface of the fibroid to sacrum was negatively correlated ( < 0.001). Patients with anterior, posterior and perirectal, and right lateral fascial edemas were associated with lower abdominal pain, sacrococcygeal pain, and leg numbness/pain, respectively.
CONCLUSION
Post-USgHIFU ablation, patients were prone to developing endopelvic fascial edema, and some of them experienced pain-related adverse events. The fibroid location, its types of contrast enhancement, the distance from the dorsal surface of the fibroid to the sacrum, and EEF were the influencing factors resulting in the endopelvic fascial edema after USgHIFU ablation.
Topics: Edema; Female; High-Intensity Focused Ultrasound Ablation; Humans; Leiomyoma; Magnetic Resonance Imaging; Pain; Retrospective Studies; Treatment Outcome; Ultrasonography, Interventional; Uterine Neoplasms
PubMed: 35995432
DOI: 10.1080/02656736.2022.2112306 -
BMJ Case Reports Nov 2015Massive oedema of the vulva appears to be a sequel of an underlying systemic disease in pregnant women. Isolated vulval oedema in pregnancy is rare. Vulval oedema has... (Review)
Review
Massive oedema of the vulva appears to be a sequel of an underlying systemic disease in pregnant women. Isolated vulval oedema in pregnancy is rare. Vulval oedema has been treated, depending on pathophysiology, with steroids, furosemide, albumin and continuous epidural analgaesia. We present a case of vulval oedema, where the oedema was confined to the labia minora in a healthy young pregnant woman. The patient was in pain and extreme discomfort due to the labial swelling, and caesarean section was being considered for delivery as the massive oedema would obstruct the birth canal. The swelling, however, resolved successfully by simple drainage. In the literature, there have been cases delivered by caesarean section as vulval swelling was causing an obstruction.
Topics: Adult; Cesarean Section; Edema; Female; Humans; Hypoalbuminemia; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Severity of Illness Index; Vulva; Vulvar Diseases
PubMed: 26538126
DOI: 10.1136/bcr-2014-206666 -
Journal of Neural Transmission (Vienna,... Mar 2024Edema as an adverse drug reaction is a commonly underestimated yet potentially debilitating condition. This study analyzes the incidence of severe psychotropic...
Edema as an adverse drug reaction is a commonly underestimated yet potentially debilitating condition. This study analyzes the incidence of severe psychotropic drug-induced edema (e.g., edema affecting the face, legs, or multiple body parts and lasting for more than 1 week, or in any case necessitating subsequent diuretic use) among psychiatric inpatients. The cases under examination are derived from an observational pharmacovigilance program conducted in German-speaking countries ("Arzneimittelsicherheit in der Psychiatrie", AMSP) from 1993 to 2016. Among the 462,661 inpatients monitored, severe edema was reported in 231 cases, resulting in an incidence of 0.05%. Edema occurred more frequently in women (80% of all cases) and older patients (mean age 51.8 years). Pregabalin had the highest incidence of severe edema, affecting 1.46‰ of patients treated with pregabalin, followed by mirtazapine (0.8‰). The majority of edema cases showed a positive response to appropriate countermeasures, such as dose reduction and drug discontinuation, and resolved by the end of the observation period. While most instances of drug-induced edema are reversible, they can have a significant impact on patient well-being and potentially result in decreased treatment adherence. It is, therefore, crucial to remain vigilant regarding risk-increasing circumstances during treatment with psychotropic drugs.
Topics: Female; Humans; Middle Aged; Adverse Drug Reaction Reporting Systems; Drug-Related Side Effects and Adverse Reactions; Edema; Pregabalin; Psychotropic Drugs; Pharmacovigilance
PubMed: 38353811
DOI: 10.1007/s00702-024-02738-6