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Addiction (Abingdon, England) Dec 2016To review the evidence base for classifying compulsive sexual behavior (CSB) as a non-substance or 'behavioral' addiction. (Review)
Review
AIMS
To review the evidence base for classifying compulsive sexual behavior (CSB) as a non-substance or 'behavioral' addiction.
METHODS
Data from multiple domains (e.g. epidemiological, phenomenological, clinical, biological) are reviewed and considered with respect to data from substance and gambling addictions.
RESULTS
Overlapping features exist between CSB and substance use disorders. Common neurotransmitter systems may contribute to CSB and substance use disorders, and recent neuroimaging studies highlight similarities relating to craving and attentional biases. Similar pharmacological and psychotherapeutic treatments may be applicable to CSB and substance addictions, although considerable gaps in knowledge currently exist.
CONCLUSIONS
Despite the growing body of research linking compulsive sexual behavior (CSB) to substance addictions, significant gaps in understanding continue to complicate classification of CSB as an addiction.
Topics: Behavior, Addictive; Compulsive Behavior; Craving; Erotica; Female; Humans; Impulsive Behavior; Libido; Male; Reward; Sexual Behavior; Unsafe Sex
PubMed: 26893127
DOI: 10.1111/add.13297 -
Reviews in Endocrine & Metabolic... Mar 2020The association between diabetes mellitus (and its micro- and macro-vascular complications) and erectile dysfunction is widely known and the presence of hypogonadism may... (Review)
Review
The association between diabetes mellitus (and its micro- and macro-vascular complications) and erectile dysfunction is widely known and the presence of hypogonadism may further complicate sexual dysfunction and quality of life, given the association between hypogonadism and reduced libido, ejaculatory disorders, and depressive symptoms. However, the recent introduction of novel antidiabetic agents with a wide range of mechanism of action may have a significant impact both on male and female sexuality directly (by inducing side effects as urinary tract infections) and indirectly (improving metabolic status and reducing diabetes complications behind sexual dysfunctions). To date only few papers are reporting the sexual effects of these treatments and, often, these are not comparable in their results. Conversely, female sexual dysfunctions are somehow under-investigated. Data on prevalence is heterogeneous and specific pathogenic mechanisms, as well as the burden of psychological factors, are still heatedly debated. The aim of this narrative review is to summarize current knowledge and stressing out the need to diagnose male and female sexual dysfunctions also in light of the impact of treatments with novel antidiabetic agents. This would highlight the still unmet needs for sexual care in a diabetes care setting and could represent an incentive for future discussions, as well as a required theoretical starting point for studies on this subject.
Topics: Animals; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Erectile Dysfunction; Female; Humans; Hypoglycemic Agents; Hypogonadism; Libido; Male; Sexual Dysfunction, Physiological
PubMed: 31863254
DOI: 10.1007/s11154-019-09535-7 -
Psychologie & Neuropsychiatrie Du... Jun 2003DHEA and its ester sulfate metabolite, DHEAS, are steroids mainly secreted by the adrenal cortex, but also within the brain where they are considered as neurosteroids.... (Review)
Review
DHEA and its ester sulfate metabolite, DHEAS, are steroids mainly secreted by the adrenal cortex, but also within the brain where they are considered as neurosteroids. No receptor was identified for DHEA or DHEAS. Their putative effects are mediated by their conversion into active sexual streroids, estradiol and testosterone, but their role is not clarified. Decreased serum levels of DHEA\DHEAS are associated with aging and have also been found in age-associated diseases. However, the results of epidemiological studies are contradictory and few therapeutic trials were published. A positive effect was found on the libido, bone status and skin in women over 70 years of age. No clear effect was evidenced on the cognitive status. Some studies showed a beneficial effect on thymic disorders, but this effect remains to be confirmed. We don't know the possible negative consequences of long-term administration of DHEA\DHEAS on cardiovascular disease and hormone-dependent cancers. Therefore, DHEA administration should not be recommended for aged people.
Topics: Adjuvants, Immunologic; Aged; Aging; Alzheimer Disease; Cognition Disorders; Dehydroepiandrosterone; Epidemiologic Studies; Female; Humans; Libido; Male; Middle Aged
PubMed: 15683947
DOI: No ID Found -
Postgraduate Medical Journal Feb 1975The role of prostaglandins in reproductive physiology is reviewed with particular emphasis on their possible importance in ovulation in humans. A possible interaction... (Review)
Review
The role of prostaglandins in reproductive physiology is reviewed with particular emphasis on their possible importance in ovulation in humans. A possible interaction between gonadal steroids, biogenic amines and prostaglandins at hypothalamic-pituitary level, in relation to the release of luteinizing hormone releasing factor, and LH, is discussed. Anomalies regarding the role of oestrogens in LH release are noted, and it is suggested that high oestrogen levels may release prostaglandins from the uterus and/or centrally in humans, in connection with the mid-cycle LH surge and ovulation. A hypothetical role for prostaglandins in sexual behaviour and premenstrual changes is discussed. The hypotheses open up new areas for clinical research to establish the role of prostaglandins in human endocrinology. The need for measurement of prostaglandin metabolites in blood and urine is emphasized.
Topics: Adolescent; Adult; Biogenic Amines; Estrogens; Female; Follicle Stimulating Hormone; Humans; Hypothalamus; Libido; Luteinizing Hormone; Menstruation; Middle Aged; Ovary; Ovulation; Pituitary Gland; Premenstrual Syndrome; Progesterone; Prostaglandins; Reproduction; Sexual Behavior; Sympathetic Nervous System; Uterus
PubMed: 1089972
DOI: 10.1136/pgmj.51.592.74 -
International Journal of Environmental... Apr 2022Recent literature has extensively examined sexual behavior during lockdown due to COVID-19. However, there are no recent studies that have considered the relationship...
Recent literature has extensively examined sexual behavior during lockdown due to COVID-19. However, there are no recent studies that have considered the relationship between body image quality, sexual arousability, and sexual anxiety. The present study has two main objectives: (1) to examine gender differences in bodily and sexual experience; and (2) the comparison of bodily and sexual experience, before and during the COVID-19 lockdown. A total of 301 adult subjects (161 women and 140 men) aged between 16 and 73 years (Mean = 37.4; S.D. = 10.3) participated in the study. Data on biographical information were collected via an online panel. The Body Uneasiness Test (BUT) and the Sexual Arousability Inventory (SAI) were used for the assessment. Univariate ANOVA showed worse scores for women, compared with men, in terms of body image avoidance, depersonalization, overall severity of body image quality, sexual arousability, and sexual anxiety dimensions. When compared against time, only women showed significant correlations between the function of sexual arousal and all parameters concerning body image alteration. Interestingly, these correlations were weak and sporadic before lockdown, but strong and numerous during lockdown. This finding suggests that the impact of COVID-19 restrictions affected the female population more, with a profound repercussion on self-image and sexual and mental well-being.
Topics: Adolescent; Adult; Aged; Body Image; COVID-19; Communicable Disease Control; Female; Humans; Libido; Male; Middle Aged; Sex Factors; Young Adult
PubMed: 35410031
DOI: 10.3390/ijerph19074351 -
American Journal of Men's Health Sep 2011
Topics: Affect; Aging; Androgens; Body Composition; Erectile Dysfunction; Humans; Libido; Male; Men's Health
PubMed: 22056944
DOI: 10.1177/1557988311416633 -
British Medical Journal May 1971
Topics: Candidiasis, Vulvovaginal; Contraceptives, Oral; Dyspareunia; Female; Humans; Libido; Norethindrone
PubMed: 5572399
DOI: 10.1136/bmj.2.5756.277-c -
Physiological Research Dec 2021Tribulus terrestris, L. (puncture vine) have been used as a folk medicine for five thousands of years, but its targets, effects, their mechanisms and application... (Review)
Review
Tribulus terrestris, L. (puncture vine) have been used as a folk medicine for five thousands of years, but its targets, effects, their mechanisms and application requires further studies. This paper reviews the provenance, constituents and properties of Tribulus terrestris, L., its general physiological and health effects, as well as the currently available knowledge concerning its influence on male and female reproductive processes and their dysfunctions. Analysis of the available publications demonstrated the influence of Tribulus terrestris on a wide spectrum of targets and physiological processe and disorders. In particular, Tribulus terrestris can be a stimulator of male and female reproductive processes at the level of central nervous system, sexual behaviour, pituitary and gonadal hormones and their receptors, gonadal functions (including ovarian follicullogenesis and spermatogenesis), improvement of the quality and quantity of gametes (at least of sperm) and fecundity. This ability of puncture vine is applicable for the improvement of man's sexual desire and sperm quality in vivo and in vitro, as well as of women's libido, activation of women's reproductive organs, fecundity, and treatment of infertility, especially that related to the polycystic ovarian syndrome.
Topics: Female; Humans; Libido; Male; Plant Extracts; Reproduction; Sexual Behavior; Tribulus
PubMed: 35199550
DOI: 10.33549/physiolres.934711 -
PloS One 2019Research has shown that romantic love can be regulated. We investigated perceptions about love regulation, because these perceptions may impact mental health and...
Research has shown that romantic love can be regulated. We investigated perceptions about love regulation, because these perceptions may impact mental health and influence love regulation application. Two-hundred eighty-six participants completed a series of items online via Qualtrics that assessed perceived ability to up- and down-regulate, exaggerate and suppress the expression of, and start and stop different love types. We also tested individual differences in perceived love regulation ability. Participants thought that they could up- but not down-regulate love in general and that they could up-regulate love in general more than down-regulate it. Participants thought that they could up-regulate infatuation less than attachment and sexual desire. Participants also thought that they could exaggerate and suppress expressions of infatuation, attachment, and sexual desire, but that they could not start and stop infatuation and attachment, or start sexual desire. The more participants habitually used cognitive reappraisal, the more they thought that they could up- and down-regulate infatuation and attachment and up-regulate sexual desire. The more participants were infatuated with their beloved, the more they thought that they could up- but not down-regulate infatuation, attachment, and sexual desire. Finally, participants thought that they could up- and down-regulate happiness more than infatuation These findings are a first step toward the development of psychoeducation techniques to correct inaccurate love regulation perceptions, which may improve mental health and love regulation in daily life.
Topics: Adult; Emotional Regulation; Female; Humans; Interpersonal Relations; Libido; Love; Male; Perception; Self Report; Sexual and Gender Minorities; Surveys and Questionnaires; Young Adult
PubMed: 31083671
DOI: 10.1371/journal.pone.0216523 -
Andrology May 2016Clinical review of the present data on the effects of selective serotonin reuptake inhibitors (SSRIs) on male fertility was the objective of the study. PubMed and Scopus... (Review)
Review
Clinical review of the present data on the effects of selective serotonin reuptake inhibitors (SSRIs) on male fertility was the objective of the study. PubMed and Scopus were searched for publications in English or Danish and reviewed. Human trials, animal studies and in vitro studies were included. Use of SSRIs negatively affects semen parameters in most studies. In some studies, SSRIs are also shown to reduce DNA integrity. SSRIs can also delay ejaculation. Depression and anxiety can cause reduced libido, erectile dysfunction and delayed ejaculation as well. The use of SSRIs seems to reduce male fertility by affecting semen parameters, although most studies have a degree of confounding by indication caused by the underlying depression.
Topics: Depressive Disorder; Ejaculation; Erectile Dysfunction; Fertility; Humans; Infertility, Male; Libido; Male; Selective Serotonin Reuptake Inhibitors
PubMed: 27019308
DOI: 10.1111/andr.12184