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Women's Health (London, England) Sep 2011Low sexual desire is a prevalent symptom, but not one frequently volunteered by women. When accompanied by distress, loss of libido is known as hypoactive sexual desire... (Review)
Review
Low sexual desire is a prevalent symptom, but not one frequently volunteered by women. When accompanied by distress, loss of libido is known as hypoactive sexual desire disorder, which can have a significant impact on a woman's wellbeing. The etiology of hypoactive sexual desire disorder is multifactorial and its management requires a combination of psychosocial and pharmacological interventions. This article outlines the assessment of patients presenting with the symptom of low sexual desire and discusses the evidence for pharmacological management.
Topics: Bupropion; Dopamine Uptake Inhibitors; Education, Medical, Continuing; Female; Humans; Libido; Menopause; Sexual Dysfunctions, Psychological; Women's Health
PubMed: 21879825
DOI: 10.2217/whe.11.54 -
Acta Dermato-venereologica Jun 2023Atopic dermatitis is a chronic, relapsing and inflammatory skin disease. The impact of atopic dermatitis on the partners living with patients has been poorly...
Atopic dermatitis is a chronic, relapsing and inflammatory skin disease. The impact of atopic dermatitis on the partners living with patients has been poorly investigated. The objective of this study was to evaluate the impact of atopic dermatitis in the daily lives of adult patients and to assess the burden of the disease on their partners. A population-based study was conducted on a representative sample of the general population of French adults aged 18 years of age using stratified, proportional sampling with a replacement design. Data were collected on 1,266 atopic dermatitis patient-partner dyads (mean age of patients 41.6 years, 723 (57.1%) women). The mean age of partners was 41.8 years. Patient burden, measured by the Atopic Dermatitis Burden Scale for Adults (ABS-A) score, was closely related to the objective atopic dermatitis severity: the mean score in the mild group (29.5) was significantly lower than in the moderate (43.9) and severe groups (48.6) (p < 0.0001). Partner burden, measured by the EczemaPartner score, was highly related to atopic dermatitis severity (p < 0.0001). Daytime sleepiness, measured by the Epworth Sleepiness Scale, showed a mean score of 9.24 in patients and 9.01 in their partners, indicating impaired sleep. Atopic dermatitis was found to decrease sexual desire in 39% and 26% of partners and patients respectively.
Topics: Adult; Humans; Female; Adolescent; Male; Dermatitis, Atopic; Quality of Life; Severity of Illness Index; Libido; Patients
PubMed: 37358393
DOI: 10.2340/actadv.v103.5285 -
Journal of Consulting and Clinical... Dec 1995Classic and contemporary approaches to the assessment of female sexuality are discussed. General approaches, assessment strategies, and models of female sexuality are... (Review)
Review
Classic and contemporary approaches to the assessment of female sexuality are discussed. General approaches, assessment strategies, and models of female sexuality are organized within the conceptual domains of sexual behaviors, sexual responses (desire, excitement, orgasm, and resolution), and individual differences, including general and sex-specific personality models. Where applicable, important trends and relationships are highlighted in the literature with both existing reports and previously unpublished data. The present conceptual overview highlights areas in sexual assessment and model building that are in need of further research and theoretical clarification.
Topics: Female; Humans; Individuality; Libido; Orgasm; Patient Care Team; Sexual Behavior; Sexual Dysfunctions, Psychological
PubMed: 8543712
DOI: 10.1037//0022-006x.63.6.891 -
British Medical Journal Aug 1971Depression, headaches, and libido were rated in 272 women before starting a contraceptive method and at intervals during the first year of use-54 were fitted with an... (Clinical Trial)
Clinical Trial
Depression, headaches, and libido were rated in 272 women before starting a contraceptive method and at intervals during the first year of use-54 were fitted with an intrauterine device (I.U.D.) and 218 used one of three oral contraceptives. Side effects caused 25% of the oral contraceptive group and 13% of the I.U.D. group to stop the method. Depression, headaches, and loss of libido were the most common reasons for stopping oral contraceptives and breakthrough bleeding was the most common reason for stopping the I.U.D.The group of women who stopped or changed their oral contraceptives during the survey were compared with the group who remained on the same oral contraceptive throughout. The former had higher mean depression and neuroticism scores at the first clinic visit and contained more women with a history of premenstrual weepiness, depression during pregnancy, outpatient psychiatric treatment, and treatment with antidepressants. Changes in the depression, headache, and libido ratings throughout the survey are presented.
Topics: Adult; Antidepressive Agents; Contraceptives, Oral; Crying; Depression; Female; Headache; Hemorrhage; Humans; Intrauterine Devices; Libido; Menstruation; Personality Inventory; Pregnancy; Pregnancy Complications; Prospective Studies; Psychotherapy
PubMed: 5565516
DOI: 10.1136/bmj.3.5773.495 -
Ugeskrift For Laeger May 2014Sexual dysfunction is a common adverse effect of antidepressant treatment and a main reason for non-compliance with treatment. Different antidepressant agents are... (Review)
Review
Sexual dysfunction is a common adverse effect of antidepressant treatment and a main reason for non-compliance with treatment. Different antidepressant agents are associated with different degrees of dysfunction, which is thought to depend on the agent's pharmacological profile. Agents with serotonergic activity, such as selective serotonin reuptake inhibitors (SSRI) and venlafaxine, yield the highest rate of sexual dysfunction. Non-SSRI agents such as duloxetine, reboxetine and mirtazapine have fewer sexual side effects than SSRI and venlafaxine. Agomelatine and bupropion are similar to placebo.
Topics: Antidepressive Agents, Second-Generation; Arousal; Depressive Disorder; Female; Humans; Libido; Male; Orgasm; Selective Serotonin Reuptake Inhibitors; Sexual Behavior; Sexual Dysfunction, Physiological
PubMed: 25352006
DOI: No ID Found -
Proceedings of the Royal Society of... Feb 1973
Topics: Cholesterol; Climacteric; Coitus; Estrogens; Female; Humans; Libido; Menopause; Osteoporosis; Phospholipids
PubMed: 4714660
DOI: No ID Found -
Journal of Sex Research Jan 2022We used the developmental systems model to deduce a definition of female early adolescent sexual desire. We evaluated a measure of this phenomenon with a secondary... (Randomized Controlled Trial)
Randomized Controlled Trial
We used the developmental systems model to deduce a definition of female early adolescent sexual desire. We evaluated a measure of this phenomenon with a secondary analysis of data from a randomized group sexual health intervention trial involving low-income, English-speaking, seventh grade Latinas enrolled in a Miami-Dade County public school (542). As part of this study, girls completed a four-item early adolescent sexual desire (EASD) measure. Study findings supported internal consistency (Cronbach's alpha = .81 to .82) and stability over a 1-month period ( = .74). Developmental sensitivity was supported by a decline in stability over 12- ( = .66) and 24-month periods ( = .56). Validity was supported by correlations with puberty changes, sexual intentions, sexting, and sexual behavior, and hypothesized mean differences associated with dating and preference for shoes culturally associated with female sexual attractiveness ( < .01). Research implications include validation work with other ethnic/racial groups and using the EASD as a starting point for a measurement continuum tracking development of sexual desire across adolescence and into adulthood. Directions for future research also include measuring the development of sexual desire in boys and transgendered youth across adolescence and into adulthood.
Topics: Adolescent; Adolescent Behavior; Adult; Female; Hispanic or Latino; Humans; Libido; Male; Schools; Sexual Behavior
PubMed: 33739211
DOI: 10.1080/00224499.2021.1891190 -
Archives of Endocrinology and Metabolism Jul 2019
Topics: Brazil; Endocrinology; Female; Humans; Libido; Testosterone
PubMed: 31340239
DOI: 10.20945/2359-3997000000153 -
Animal : An International Journal of... Aug 2018l-Arginine is a nutritionally essential amino acid for spermatogenesis and plays versatile roles in animal health and can be utilized as a potential agent to improve...
l-Arginine is a nutritionally essential amino acid for spermatogenesis and plays versatile roles in animal health and can be utilized as a potential agent to improve reproductive performance of boars under high ambient temperature. The present study aimed to determine whether dietary l-arginine could alleviate heat stress-induced infertility in boars. In all, 20 boars (PIC 1040; 248.59±3.84 kg BW and 407.65±6.40 days of age) were selected and randomly assigned to four groups (group 0.0%, basal diet; group 0.6%, 0.8% or 1.0%, basal diet added with 0.6%, 0.8% or 1.0% l-arginine (wt:wt), respectively.) The four diets were made isonitrogenous by addition of appropriate amounts of l-alanine. Boars were pre-fed the corresponding experimental diet for 42 days. Then, the semen characteristics and libido were accessed for 6 weeks during the hot summer period (25.5° to 33.0°C). Results show that dietary l-arginine remarkably improved sperm motility, normality, total sperm number and effective total sperm number. Also, dietary l-arginine improved semen antioxidant capacity, such as decrease of malondialdehyde and 8-Hydroxy-2'-deoxyguanosine content in sperm (P<0.05), increase of the ratio of glutathione and oxidized glutathione, total antioxidant capacity, glutathione peroxidase and catalase activities in seminal plasma (P<0.05). Most of mitochondria contained intact ultrastructure in l-arginine-supplemented group which also accompany with higher ATP content than the 0.0% group. The boars fed 0.8% l-arginine show increased levels of estradiol-17β and testosterone and exhibit improved libido performance than boars in the 0.0% group. Adding dietary l-arginine linearly increased (P=0.002) nitric oxide content (as l-arginine increased). The scrotal surface temperature in the 0.6%, 0.8% and 1.0% group were decreased by 0.9°C, 0.9°C and 0.4°C, respectively, compared with the 0.0% group. l-Arginine levels caused linear effect on semen quality and antioxidant capacity, also caused quadratic effect on libido performance. During the hot summer months, the predicted optimal l-arginine levels for best semen quality and antioxidant capacity was 0.8% to 1.0% and for best libido performance was 0.8%. It can be concluded that l-arginine can be used as an effective agent to alleviate heat stress-induced infertility of boar, and that 0.8% to 1.0% can be considered as the optimum dosage.
Topics: Animal Feed; Animals; Arginine; Libido; Male; Semen; Semen Analysis; Sperm Motility; Spermatozoa; Swine; Temperature
PubMed: 29198215
DOI: 10.1017/S1751731117003147 -
Oncology (Williston Park, N.Y.) Mar 2004Androgen deprivation, as a form of treatment for prostate cancer, has been used for decades. Within the last decade, however, its use has increased significantly.... (Review)
Review
Androgen deprivation, as a form of treatment for prostate cancer, has been used for decades. Within the last decade, however, its use has increased significantly. Therefore, it is incumbent upon the physician to be familiar with the side effects associated with this treatment. Some of these side effects (eg, osteoporosis, changes in lipid profiles, and anemia) may be associated with significant morbidity, whereas others (eg, impotence, decreased libido, fatigue, and hot flashes) primarily affect the patient's quality of life. Prevention strategies and treatments exist for many of these side effects. In addition, alternative forms of antiandrogen therapy such as intermittent hormone ablation and antiandrogen monotherapy may be effective, with the added benefit of minimizing side effects. This review focuses on the wide range of side effects associated with androgen ablation as well as preventive and treatment strategies.
Topics: Androgen Antagonists; Anemia; Bone Density; Cognition; Diet Therapy; Hot Flashes; Humans; Libido; Lipids; Male; Osteoporosis; Prostatic Neoplasms; Quality of Life; Weight Gain
PubMed: 15065701
DOI: No ID Found