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Physiological Reports May 2023Limited research exists examining how resistance training to failure affects applied outcomes and single motor unit characteristics in previously trained individuals.... (Randomized Controlled Trial)
Randomized Controlled Trial
Limited research exists examining how resistance training to failure affects applied outcomes and single motor unit characteristics in previously trained individuals. Herein, resistance-trained adults (24 ± 3 years old, self-reported resistance training experience was 6 ± 4 years, 11 men and 8 women) were randomly assigned to either a low-repetitions-in-reserve (RIR; i.e., training near failure, n = 10) or high-RIR (i.e., not training near failure, n = 9) group. All participants implemented progressive overload during 5 weeks where low-RIR performed squat, bench press, and deadlift twice weekly and were instructed to end each training set with 0-1 RIR. high-RIR performed identical training except for being instructed to maintain 4-6 RIR after each set. During week 6, participants performed a reduced volume-load. The following were assessed prior to and following the intervention: (i) vastus lateralis (VL) muscle cross-sectional area (mCSA) at multiple sites; (ii) squat, bench press, and deadlift one-repetition maximums (1RMs); and (iii) maximal isometric knee extensor torque and VL motor unit firing rates during an 80% maximal voluntary contraction. Although RIR was lower in the low- versus high-RIR group during the intervention (p < 0.001), total training volume did not significantly differ between groups (p = 0.222). There were main effects of time for squat, bench press, and deadlift 1RMs (all p-values < 0.05), but no significant condition × time interactions existed for these or proximal/middle/distal VL mCSA data. There were significant interactions for the slope and y-intercept of the motor unit mean firing rate versus recruitment threshold relationship. Post hoc analyses indicated low-RIR group slope values decreased and y-intercept values increased after training suggesting low-RIR training increased lower-threshold motor unit firing rates. This study provides insight into how resistance training in proximity to failure affects strength, hypertrophy, and single motor unit characteristics, and may inform those who aim to program for resistance-trained individuals.
Topics: Male; Humans; Adult; Female; Young Adult; Resistance Training; Quadriceps Muscle; Adaptation, Physiological; Acclimatization; Hypertrophy; Muscle Strength; Muscle, Skeletal
PubMed: 37144554
DOI: 10.14814/phy2.15679 -
Journal of Intelligence Sep 2021Cultural intelligence is one's ability to adapt when confronted with problems arising in interactions with people or artifacts of diverse cultures. In this study, we...
Cultural intelligence is one's ability to adapt when confronted with problems arising in interactions with people or artifacts of diverse cultures. In this study, we conduct an initial construct-validation and assessment of a maximum-performance test of cultural intelligence. We assess the psychometric properties of the test and also correlate the test with other measures with which it might be expected there would be some connection. We found that our test was internally consistent and correlated significantly with maximum-performance tests of abilities but generally less or not at all with typical-performance tests, including cultural intelligence and openness to experience. However, our test appears to be distinct in what it measures from the other tests of cognitive abilities. The results lead us to suggest that cultural intelligence may have both maximum-performance and typical-performance aspects.
PubMed: 34564293
DOI: 10.3390/jintelligence9030045 -
Respiratory Care May 2021This systematic literature review summarizes the impact of smoking on maximal oxygen uptake (maximum [Formula: see text]). (Review)
Review
BACKGROUND
This systematic literature review summarizes the impact of smoking on maximal oxygen uptake (maximum [Formula: see text]).
METHODS
Full-text articles were retrieved if the abstract met the assigned criteria. A total of 9 articles were included in the final review based on the inclusion and exclusion criteria. These included articles assessed the effects of tobacco smoking on maximum [Formula: see text] values.
RESULTS
Half of the articles reported a significant difference in maximum [Formula: see text] scores between smokers and nonsmokers, with smokers having a lower maximum [Formula: see text]. The other half of the articles did not identify significant differences between smokers and nonsmokers. One study found a significant difference in maximum [Formula: see text] in only one age group (ie, 20-29 y), but not any of the other age groups.
CONCLUSIONS
More research is needed on the effects of smoking on maximum [Formula: see text] to better understand any relationships or causations.
Topics: Humans; Oxygen; Oxygen Consumption; Smoking; Tobacco Smoking
PubMed: 33593934
DOI: 10.4187/respcare.08406 -
Entropy (Basel, Switzerland) May 2023Maximum efficiency and maximum net power output are some of the most important goals to reach the optimal conditions of organic Rankine cycles. This work compares two...
Maximum efficiency and maximum net power output are some of the most important goals to reach the optimal conditions of organic Rankine cycles. This work compares two objective functions, the maximum efficiency function, β, and the maximum net power output function, ω. The van der Waals and PC-SAFT equations of state are used to calculate the qualitative and quantitative behavior, respectively. The analysis is performed for a set of eight working fluids, considering hydrocarbons and fourth-generation refrigerants. The results show that the two objective functions and the maximum entropy point are excellent references for describing the optimal organic Rankine cycle conditions. These references enable attaining a zone where the optimal operating conditions of an organic Rankine cycle can be found for any working fluid. This zone corresponds to a temperature range determined by the boiler outlet temperature obtained by the maximum efficiency function, maximum net power output function, and maximum entropy point. This zone is named the optimal temperature range of the boiler in this work.
PubMed: 37372227
DOI: 10.3390/e25060882 -
Journal of Intelligence Aug 2022We administered both maximum-performance and typical-performance assessments of cultural intelligence to 114 undergraduates in a selective university in the Northeast of...
We administered both maximum-performance and typical-performance assessments of cultural intelligence to 114 undergraduates in a selective university in the Northeast of the United States. We found that cultural intelligence could be measured by both maximum-performance and typical-performance tests of cultural intelligence. Cultural intelligence as assessed by a maximum-performance measure is largely distinct from the construct as assessed by a typical-performance measure. The maximum-performance test, the Sternberg Test of Cultural Intelligence (SCIT), showed high internal consistency and inter-rater reliability. Sections with problems from two content domains-Business (SCIT-B) and Leisure (SCIT-L) activities-were highly intercorrelated, suggesting they measured largely the same construct. The SCIT showed substantial correlations with another maximum-performance measure of cultural intelligence, Views-on-Culture. It also was correlated, at more modest levels, with fluid intelligence and personal intelligence tests. Factorially, the (a) maximum-performance cultural intelligence tests, (b) typical-performance cultural intelligence test and a test of openness to experience, and (c) fluid intelligence tests formed three separate factors.
PubMed: 35997410
DOI: 10.3390/jintelligence10030054 -
Journal of Mathematical Biology Jul 2022In conservation biology, phylogenetic diversity (PD) provides a way to quantify the impact of the current rapid extinction of species on the evolutionary 'Tree of Life'....
In conservation biology, phylogenetic diversity (PD) provides a way to quantify the impact of the current rapid extinction of species on the evolutionary 'Tree of Life'. This approach recognises that extinction not only removes species but also the branches of the tree on which unique features shared by the extinct species arose. In this paper, we investigate three questions that are relevant to PD. The first asks how many sets of species of given size k preserve the maximum possible amount of PD in a given tree. The number of such maximum PD sets can be very large, even for moderate-sized phylogenies. We provide a combinatorial characterisation of maximum PD sets, focusing on the setting where the branch lengths are ultrametric (e.g. proportional to time). This leads to a polynomial-time algorithm for calculating the number of maximum PD sets of size k by applying a generating function; we also investigate the types of tree shapes that harbour the most (or fewest) maximum PD sets of size k. Our second question concerns optimising a linear function on the species (regarded as leaves of the phylogenetic tree) across all the maximum PD sets of a given size. Using the characterisation result from the first question, we show how this optimisation problem can be solved in polynomial time, even though the number of maximum PD sets can grow exponentially. Our third question considers a dual problem: If k species were to become extinct, then what is the largest possible loss of PD in the resulting tree? For this question, we describe a polynomial-time solution based on dynamical programming.
Topics: Algorithms; Biodiversity; Biological Evolution; Phylogeny
PubMed: 35842488
DOI: 10.1007/s00285-022-01779-3 -
Journal of Physical Therapy Science Oct 2021[Purpose] The purpose of this study was to investigate the factors of ankle instability by using Cumberland ankle instability tool (CAIT), which have been frequently...
[Purpose] The purpose of this study was to investigate the factors of ankle instability by using Cumberland ankle instability tool (CAIT), which have been frequently used as ankle instability tools. The participants were divided into the normal ankle group and the instability ankle group. Maximum strength, proprioception, dynamic balance and maximum rage of joint motion were compared in order to find out factors of instability in the questionnaires. [Participants and Methods] A total of 44 participants were classified into the control (CON) group and the chronic ankle instability (CAI) group according to questionnaire types. Muscle strength, proprioception, dynamic balance and maximum joint angle were measured. The independent t-test was used. [Results] In the case of maximum ankle strength, it showed significance in CON group and CAI group ankle dorsiflexion and plantarflexion. In proprioception, it showed significance in CON group and CAI group. In dynamic balance, it showed significance in anterior (ANT) direction of the CON group and CAI group. Maximum joint angle produced significance in dorsiflexion of CON group and CAI group. [Conclusion] Information on maximum strength, proprioception, dynamic balance of anterior direction, and maximum joint angle of dorsiflexion is available through questionnaire CAIT.
PubMed: 34658514
DOI: 10.1589/jpts.33.728 -
Antioxidants (Basel, Switzerland) Jun 2022Both light intensity and spectrum (280-800 nm) affect photosynthesis and, consequently, the formation of reactive oxygen species (ROS) during photosynthetic electron... (Review)
Review
Both light intensity and spectrum (280-800 nm) affect photosynthesis and, consequently, the formation of reactive oxygen species (ROS) during photosynthetic electron transport. ROS, together with antioxidants, determine the redox environment in tissues and cells, which in turn has a major role in the adjustment of metabolism to changes in environmental conditions. This process is very important since there are great spatial (latitude, altitude) and temporal (daily, seasonal) changes in light conditions which are accompanied by fluctuations in temperature, water supply, and biotic stresses. The blue and red spectral regimens are decisive in the regulation of metabolism because of the absorption maximums of chlorophylls and the sensitivity of photoreceptors. Based on recent publications, photoreceptor-controlled transcription factors such as ELONGATED HYPOCOTYL5 (HY5) and changes in the cellular redox environment may have a major role in the coordinated fine-tuning of metabolic processes during changes in light conditions. This review gives an overview of the current knowledge of the light-associated redox control of basic metabolic pathways (carbon, nitrogen, amino acid, sulphur, lipid, and nucleic acid metabolism), secondary metabolism (terpenoids, flavonoids, and alkaloids), and related molecular mechanisms. Light condition-related reprogramming of metabolism is the basis for proper growth and development of plants; therefore, its better understanding can contribute to more efficient crop production in the future.
PubMed: 35883801
DOI: 10.3390/antiox11071311 -
PeerJ 2020Understanding characteristics of torso motion and arm swing of older adults is important. A comprehensive database of three-dimensional thoracic and pelvic kinematics...
Understanding characteristics of torso motion and arm swing of older adults is important. A comprehensive database of three-dimensional thoracic and pelvic kinematics and arm swing maximum velocity of older adults during overground walking is still lacking. Moreover, the relationships between these variables are not fully understood. Therefore, we investigated age and gender effects of three-dimensional thoracic and pelvic ranges of motion and arm swing maximum velocity in 113 healthy old adults (aged 60-89 years) in a 2-min walk test using APDM Movement Monitoring inertial sensor system by two-way ANOVA, and post hoc Bonferroni correction was applied for multiple comparisons between age groups. A paired -test was used to study the side preference of arm swing maximum velocity. The relationships between variables were investigated via multiple linear regression models. In general, thoracic and pelvic motions showed reduced amplitude with aging. Gait speed, pelvis coronal plane motion and arm swing maximum velocity significantly declined with age. Only the pelvic sagittal plane motion showed a gender main effect. Coronal plane motions of the thorax and pelvis were closely associated, as were sagittal plane motions. Thoracic coronal plane motion was the significant variable influencing pelvic transverse plane motion and vice versa. Gait speed, pelvic coronal and transverse plane motions and thorax sagittal plane motion were significant independent variables that influenced dominant arm maximum velocity. A larger maximum velocity was seen in the left arm. This investigation is valuable for better understanding of gait phenomena and will contribute to identification of gait dysfunction and development of rehabilitation measures.
PubMed: 32704440
DOI: 10.7717/peerj.9329 -
JAMA Network Open Jun 2023Prior authorization (PA) requirements for buprenorphine are associated with lower provision of the medication for the treatment of opioid use disorder (OUD). While... (Review)
Review
IMPORTANCE
Prior authorization (PA) requirements for buprenorphine are associated with lower provision of the medication for the treatment of opioid use disorder (OUD). While Medicare plans have eliminated PA requirements for buprenorphine, many Medicaid plans continue to require them.
OBJECTIVE
To describe and classify buprenorphine coverage requirements based on thematic analysis of state Medicaid PA forms.
DESIGN, SETTING, AND PARTICIPANTS
This qualitative study used a thematic analysis of 50 states' Medicaid PA forms for buprenorphine between November 2020 and March 2021. Forms were obtained from the jurisdiction's Medicaid websites and assessed for features suggesting barriers to buprenorphine access. A coding tool was developed based on a review of a sample of forms, including fields for behavioral health treatment recommendations or mandates, drug screening requirements, and dosage limitations.
MAIN OUTCOMES AND MEASURES
Outcomes included PA requirements for different buprenorphine formulations. Additionally, PA forms were evaluated for various criteria such as behavioral health, drug screenings, dose-related recommendations or mandates or patient education.
RESULTS
Among the total of 50 US states in the analysis, most states' Medicaid plans required PA for at least 1 formulation of buprenorphine. However, the majority did not require a PA for buprenorphine-naloxone. Four key themes of coverage requirements were identified: restrictive surveillance (eg, requirements for urine drug screenings, random drug screenings, pill counts), behavioral health treatment recommendations or mandates (eg, mandatory counseling or 12-step meeting attendance), interfering with or restricting medical decision-making (eg, maximum daily dosages of 16 mg, requiring additional steps for dosages higher than 16 mg), and patient education (eg, information about adverse effects and interactions with other medications). Eleven states (22%) required urine drug screenings, 6 states (12%) required random urine drug screenings, and 4 states (8%) required pill counts. Fourteen states' forms (28%) recommended therapy, and 7 (14%) required therapy, counseling, or participation in group sessions. Eighteen states (36%) specified dosage maximums; among them, 11 (22%) required additional steps for a daily dosage higher than 16 mg.
CONCLUSION
In this qualitative study of state Medicaid PA requirements for buprenorphine, themes were identified that included patient surveillance with drug screenings and pill counts, behavioral health treatment recommendations or mandates, patient education, and dosing guidance. These results suggest that state Medicaid plans' buprenorphine PA requirements for OUD are in conflict with existing evidence and may negatively affect states' efforts to address the opioid overdose crisis.
Topics: Aged; Humans; United States; Buprenorphine; Medicaid; Prior Authorization; Medicare; Buprenorphine, Naloxone Drug Combination; Opioid-Related Disorders
PubMed: 37318805
DOI: 10.1001/jamanetworkopen.2023.18487