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Clinical Microbiology Reviews Jul 2018This document outlines a comprehensive practical approach to a laboratory quality management system (QMS) by describing how to operationalize the management and... (Review)
Review
This document outlines a comprehensive practical approach to a laboratory quality management system (QMS) by describing how to operationalize the management and technical requirements described in the ISO 15189 international standard. It provides a crosswalk of the ISO requirements for quality and competence for medical laboratories to the 12 quality system essentials delineated by the Clinical and Laboratory Standards Institute. The quality principles are organized under three main categories: quality infrastructure, laboratory operations, and quality assurance and continual improvement. The roles and responsibilities to establish and sustain a QMS are outlined for microbiology laboratory staff, laboratory management personnel, and the institution's leadership. Examples and forms are included to assist in the real-world implementation of this system and to allow the adaptation of the system for each laboratory's unique environment. Errors and nonconforming events are acknowledged and embraced as an opportunity to improve the quality of the laboratory, a culture shift from blaming individuals. An effective QMS encourages "systems thinking" by providing a process to think globally of the effects of any type of change. Ultimately, a successful QMS is achieved when its principles are adopted as part of daily practice throughout the total testing process continuum.
Topics: Clinical Laboratory Services; Microbiology; Quality Control
PubMed: 29720490
DOI: 10.1128/CMR.00062-17 -
MBio Jul 2020
Topics: Black or African American; Humans; Microbiology; Periodicals as Topic
PubMed: 32737071
DOI: 10.1128/mBio.01998-20 -
Research in Microbiology Sep 2007
Topics: Bacteriophages; History, 20th Century; History, 21st Century; Microbiology
PubMed: 17764907
DOI: 10.1016/j.resmic.2007.07.001 -
Proceedings of the National Academy of... Mar 1994
Topics: Bacteria; Microbiology; Phylogeny
PubMed: 8127851
DOI: 10.1073/pnas.91.5.1601 -
Research in Microbiology Dec 2015
Topics: Environmental Microbiology; Genomics; Microbiology; Research
PubMed: 26493328
DOI: 10.1016/j.resmic.2015.09.007 -
Annual Review of Microbiology 2012This review focuses on the early years of molecular studies of bacterial chemotaxis and motility, beginning in the 1960s with Julius Adler's pioneering work. It... (Review)
Review
This review focuses on the early years of molecular studies of bacterial chemotaxis and motility, beginning in the 1960s with Julius Adler's pioneering work. It describes key observations that established the field and made bacterial chemotaxis a paradigm for the molecular understanding of biological signaling. Consideration of those early years includes aspects of science seldom described in journals: the accidental findings, personal interactions, and scientific culture that often drive scientific progress.
Topics: Animals; Bacterial Physiological Phenomena; Chemotaxis; History, 20th Century; Humans; Microbiology
PubMed: 22994495
DOI: 10.1146/annurev-micro-092611-150120 -
Revue Scientifique Et Technique... Sep 1991Salmonellae are part of the bacterial flora normally found in Man and animals, although the frequency of occurrence is variable, reflecting the general level of... (Review)
Review
Salmonellae are part of the bacterial flora normally found in Man and animals, although the frequency of occurrence is variable, reflecting the general level of Salmonella in food, water and the environment. They are widely disseminated into environments which have been disturbed by human activities. Wildlife may harbour the organisms but do not appear to be a major conduit by which the organisms enter the human and animal food chain. In areas associated with Man, salmonellae in wild animals and birds reflect the serovars disseminated into the environment. Seasonal changes in infection occur, and the capacity of the organisms to survive in nature varies. Water plays an important role in the spread of the organisms to Man and animals. Control of salmonellae must start with a significant decrease in the number of organisms which are discharged into the environment.
Topics: Animal Feed; Animals; Animals, Domestic; Animals, Wild; Birds; Environmental Microbiology; Food Microbiology; Humans; Reptiles; Salmonella; Salmonella Infections; Sewage; Water Microbiology
PubMed: 1782428
DOI: No ID Found -
Scientific Reports Jun 2024Virtual Reality (VR) laboratories are a new pedagogical approach to support psychomotor skills development in undergraduate programmes to achieve practical competency....
Virtual Reality (VR) laboratories are a new pedagogical approach to support psychomotor skills development in undergraduate programmes to achieve practical competency. VR laboratories are successfully used to carry out virtual experiments in science courses and for clinical skills training in professional courses. This paper describes the development and evaluation of a VR-based microbiology laboratory on Head-Mounted Display (HMD) for undergraduate students. Student and faculty perceptions and expectations were collected to incorporate into the laboratory design. An interactive 3-dimensional VR laboratory with a 360° view was developed simulating our physical laboratory setup. The laboratory environment was created using Unity with the (created) necessary assets and 3D models. The virtual laboratory was designed to replicate the physical laboratory environment as suggested by the students and faculty. In this VR laboratory, six microbiology experiments on Gram staining, bacterial streaking, bacterial motility, catalase test, oxidase test and biochemical tests were placed on the virtual platform. First-year biomedical science students were recruited to evaluate the VR laboratory. Students' perception of the virtual laboratory was positive and encouraging. About 70% of the students expressed they felt safe using the VR laboratory and that it was engaging. They felt that the VR laboratory provided an immersive learning experience. They appreciated that they could repeat each experiment multiple times without worrying about mistakes or mishaps. They could personalise their learning by concentrating on the specific experiments. Our in-house VR-based microbiology laboratory was later extended to other health professions programmes teaching microbiology.
Topics: Virtual Reality; Humans; Microbiology; Laboratories; Clinical Competence; Female; Male
PubMed: 38834815
DOI: 10.1038/s41598-024-63601-y -
Annals of the Academy of Medicine,... Jul 2005Infectious diseases were rife during the early years of the Singapore Medical College, which was established in 1905. The current Department of Microbiology in the...
Infectious diseases were rife during the early years of the Singapore Medical College, which was established in 1905. The current Department of Microbiology in the National University of Singapore (NUS) has its historical roots in the Departments of Bacteriology and Parasitology, which were established in 1925 and 1950 respectively. With the achievements since its inception, and with its present research focus on Infectious Diseases, Immunology, Applied and Environmental Microbiology, it is poised to face the microbiological challenges of the 21st century. Over the decades, the structure of the medical microbiology course in NUS has modernised, culminating in the current emphasis on its practical utility in clinical practice. Coordinated by the Department of Microbiology, the Microbiology and Infectious Diseases module and the Immunology module both adopt integrated multidisciplinary approaches that aim to introduce students to the language and fundamental concepts in microbiology, infectious diseases and immunology.
Topics: Communicable Diseases; Education, Medical; History of Medicine; History, 20th Century; Humans; Microbiology; Schools, Medical; Singapore; Specialization
PubMed: 16010388
DOI: No ID Found -
Journal of the Royal College of... 2000
Topics: Curriculum; Education, Medical; Humans; Infection Control; Microbiology; Professional Competence
PubMed: 11005062
DOI: No ID Found