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European Annals of Otorhinolaryngology,... Jan 2021Fibroma of the tendon sheath (FTS) is a rare benign tumour typically occurring in the extremities, but very rarely involving in the neck.
INTRODUCTION
Fibroma of the tendon sheath (FTS) is a rare benign tumour typically occurring in the extremities, but very rarely involving in the neck.
CASE REPORT
A 22-year-old male presented with a large painless mass of the right oropharynx. Magnetic resonance imaging (MRI) showed a well-circumscribed 7cm lesion in the right prestyloid space. The lesion was completely removed surgically. Histopathological examination revealed a fibroma of the tendon sheath of the stylohyoid muscle.
DISCUSSION
These tumours generally arise in the extremities of adults. To our knowledge, this is the first reported case of FTS in the neck.
Topics: Adult; Fibroma; Humans; Magnetic Resonance Imaging; Male; Neck; Neck Muscles; Tendons; Young Adult
PubMed: 32307266
DOI: 10.1016/j.anorl.2020.03.010 -
Asian Journal of Surgery May 2023
Topics: Humans; Female; Carcinoma; Fibroma; Breast Neoplasms
PubMed: 36428135
DOI: 10.1016/j.asjsur.2022.11.053 -
Asian Journal of Surgery Nov 2022
Topics: Child; Fibroma; Humans; Hyperplasia; Skin
PubMed: 35597751
DOI: 10.1016/j.asjsur.2022.05.023 -
BMC Musculoskeletal Disorders Feb 2023The purpose of our study was to explore the sonographic characteristics of fibromas of the tendon sheath of the hand and wrist and to evaluate the value of high...
BACKGROUND
The purpose of our study was to explore the sonographic characteristics of fibromas of the tendon sheath of the hand and wrist and to evaluate the value of high frequency ultrasound in the diagnosis of FTS.
METHODS
We retrospectively reviewed the sonography of 42 patients with surgically proven FTS, including one with a relapsing tumor (43 lesions in total). The location, size, distribution, relationship with the surrounding tissue, two-dimensional gray-scale sonographic appearance and internal color blood flow of all lesions were analysed.
RESULTS
The maximum diameter ranged from 0.4 to 2.8 cm, with an average of 1.5 ± 0.6 cm. Twenty-eight lesions (65%) were associated with an adjacent tendon, while the other 15 lesions (35%) were next to the joint. Spindle or oval lesions were common, followed by irregular shape. The nodules with clear boundaries were hypoechoic and had posterior echo enhancement. Thirty-seven lesions (86%) were homogeneous, while 6 lesions (14%) had cystic components with no echo inside. Seventeen lesions (40%) had a large amount of blood flow. Nine lesions (20%) had a small amount of blood flow. The other 17 lesions (40%) had no significant blood flow.
CONCLUSIONS
The diagnosis of fibroma of the tendon sheath can be considered when ultrasound examination reveals a focal nodular mass adjacent to a tendon sheath with homogeneous hypoechogenicity and no or small or large amounts of blood flow.
Topics: Humans; Wrist; Retrospective Studies; Neoplasm Recurrence, Local; Tendons; Fibroma; Ultrasonography
PubMed: 36823608
DOI: 10.1186/s12891-023-06250-y -
Archives of Pathology & Laboratory... Mar 2000Calcifying fibrous pseudotumor is a rare lesion of uncertain histogenesis that has a unique histologic appearance. We report herein a case of a 24-year-old woman with a... (Review)
Review
Calcifying fibrous pseudotumor is a rare lesion of uncertain histogenesis that has a unique histologic appearance. We report herein a case of a 24-year-old woman with a mass on the right posterior side of the neck. Magnetic resonance imaging with contrast showed a well-circumscribed mass between the right splenius and semispinalis cervicis muscles; the study suggested high collagen content. Simple excision was performed. The histologic findings were diagnostic of calcifying fibrous pseudotumor. Our review of 19 previously reported cases suggests that a good outcome is expected when a diagnosis of calcifying fibrous pseudotumor is made.
Topics: Adult; Calcinosis; Female; Fibroma; Head and Neck Neoplasms; Humans; Magnetic Resonance Imaging; Treatment Outcome
PubMed: 10705402
DOI: 10.5858/2000-124-0435-CFPOTN -
Actas Dermo-sifiliograficas Nov 2015
Review
Topics: Fibroma; Hand; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Invasiveness; Ossification, Heterotopic; Scalp; Soft Tissue Neoplasms
PubMed: 26076876
DOI: 10.1016/j.ad.2015.04.012 -
The British Journal of Ophthalmology May 1989Three patients aged 15 to 40 years with fibromatosis of the periorbital region were studied. A history of acute onset, preceding trauma, and pain associated with a...
Three patients aged 15 to 40 years with fibromatosis of the periorbital region were studied. A history of acute onset, preceding trauma, and pain associated with a palpable mass were typical features. Rapid recurrence followed surgical excision. Misdiagnosis is common in this benign disease and may lead to unnecessary examinations for malignancy. Surgical excision or debulking of these masses is indicated for diagnosis and pain relief, but long-term follow-up indicates that these lesions will often spontaneously resolve with time.
Topics: Adolescent; Adult; Female; Fibroma; Humans; Neoplasm Recurrence, Local; Orbital Neoplasms
PubMed: 2730860
DOI: 10.1136/bjo.73.5.373 -
Journal of the American College of... Jun 2015Papillary fibroelastomas (PFE) are benign neoplasms with little available outcome data.
BACKGROUND
Papillary fibroelastomas (PFE) are benign neoplasms with little available outcome data.
OBJECTIVES
This study sought to describe the frequency and clinical course of patients with surgically removed PFE and echocardiographically suspected, but unoperated, PFE.
METHODS
Mayo Clinic pathology and echocardiography databases (January 1, 1995, to December 31, 2010) were queried, resulting in 511 patients: group 1 (n = 185), including patients with surgically removed, histopathologically confirmed PFE; group 1a (n = 94; 51%) with PFE removed at primary surgery; and group 1b (n = 91; 49%) with PFE removal at time of another cardiac surgery. Group 2 (n = 326) patients had echocardiographic evidence of PFE but no cardiac surgery to remove PFE.
RESULTS
Group 1 had mean age of 63 ± 14 years (116 women [63%]). During the study period, we identified 112 cardiac myxomas in the pathology database and 142 in the echocardiographic database. Mean age in group 2 was 67 ± 14 years (162 women [50%]). PFE occurred most commonly on cardiac valves (n = 400 [78%]). In group 1, transient ischemic attack or stroke was the presenting symptom in 58 patients (32%). With surgical removal of valvular PFE, the valve was preserved in 92 (98%). Recurrence was documented in 3 patients (1.6%). Follow-up stroke risk in groups 1, 1a, and 1b at 1 year was 2%, 0%, and 4%; at 5 years, 8%, 5%, and 11%, respectively. Cerebrovascular accident risk in group 2 at 1 and 5 years was 6% and 13%.
CONCLUSIONS
In patients with echocardiographically suspected PFE who do not undergo surgical removal, rates of cerebrovascular accident and mortality are increased.
Topics: Aged; Cardiac Surgical Procedures; Echocardiography; Female; Fibroma; Follow-Up Studies; Heart Neoplasms; Heart Valves; Humans; Male; Minnesota; Prognosis; Retrospective Studies
PubMed: 26046736
DOI: 10.1016/j.jacc.2015.03.569 -
Neurosurgery Mar 2021Neuromuscular choristoma (NMC) is a peripheral nerve malformation frequently associated with a fibromatosis (NMC-DTF) that mimics sporadic desmoid-type fibromatosis...
BACKGROUND
Neuromuscular choristoma (NMC) is a peripheral nerve malformation frequently associated with a fibromatosis (NMC-DTF) that mimics sporadic desmoid-type fibromatosis (DTF). Sporadic DTF is often managed conservatively but its clinical behavior varies. CTNNB1 mutational subtypes in sporadic DTF have prognostic value. We have previously identified CTNNB1 mutations in NMC, and 3 paired NMC-DTF but the clinical behavior of NMC-DTF is poorly understood.
OBJECTIVE
To evaluate patients with NMC-DTF to determine (1) CTNNB1 mutational subtypes in NMC-DTF, and (2) associated clinical behavior and response to treatment.
METHODS
Retrospective review of clinical, imaging, and pathologic features of patients with NMC and NMC-DTF, and molecular testing for CTNNB1 mutations.
RESULTS
Among 7 patients with NMC of the sciatic nerve (median age: 18 yr), NMC-DTF (mean size 10.7 cm) developed shortly following NMC biopsy (N = 5) or spontaneously (N = 2): 6 NMC-DTF had CTNNB1 p.S45X mutations and 1 NMC-DTF had a p.T41A mutation. All patients with CTNNB1-p.S45-mutated NMC-DTF developed local progression after wide local excision or active surveillance, including one distal metachronous NMC-DTF. No patient had spontaneous disease stabilization. Following adjuvant radiation or systemic therapy, disease stabilization was achieved in 4 (of 6) patients. One patient progressed on sorafenib treatment.
CONCLUSION
NMC-DTF frequently contain CTNNB1 p.S45 mutations, behave aggressively, and require adjuvant therapies for disease stabilization. We now use imaging alone to diagnose NMC, and routinely surveille the NMC-affected nerve segment to identify early NMC-DTF. In contrast to sporadic DTF, earlier adoption of systemic therapeutic strategies may be required for optimal disease management of NMC-DTF.
Topics: Adolescent; Adult; Choristoma; Female; Fibroma; Humans; Male; Middle Aged; Muscle, Skeletal; Mutation; Peripheral Nerves; Prognosis; Retrospective Studies; Young Adult; beta Catenin
PubMed: 33442732
DOI: 10.1093/neuros/nyaa534 -
Medicine Mar 2018Aggressive fibromatosis (AF) of abdominal wall is also called desmoid tumor, ligament tumor, fibrous tissue tumor hyperplasia, tendon membrane fibroma or soft tissue... (Review)
Review
RATIONALE
Aggressive fibromatosis (AF) of abdominal wall is also called desmoid tumor, ligament tumor, fibrous tissue tumor hyperplasia, tendon membrane fibroma or soft tissue ligament fibroma, etc. Aggressive fibromatosis of abdominal wall was first described by MacFarlane in 1832, and it was named for the first time by Muller according to its general appearance and texture in 1838. This disease has been mistaken for a benign lesions for a long time because when the cells were examined by pathology often show normal mitosis, and distant metastases are not found clinically, but actually the disease is locally invasive and shows a local invasive growth. So it is a rare low-grade malignant soft tissue tumor. At present, the main treatment for the disease is operation, and radiotherapy and hormone therapy have a certain effect, but these therapies are not ideal.
PATIENT CONCERNS
A 32-year-old woman, who underwent cesarean section three years ago came to the hospital for finding a mass on abdominal wall for half a month.
DIAGNOSES
Mass of abdominal wall.
INTERVENTIONS
Underwent surgery.
OUTCOMES
Pathology: The lesion is aggressive fibromatosis of abdominal wall (ligament tumor of abdominal wall).
LESSONS
We discussed the particularity of its clinical characteristics, treatment strategies and prognosis combined with literature review, and we think the surgeons need to pay high attention to this disease and make more patients get timely, correct and reasonable treatment, so as to improve the quality of life.
Topics: Abdominal Wall; Adult; Diagnostic Errors; Female; Fibromatosis, Abdominal; Fibromatosis, Aggressive; Humans
PubMed: 29517699
DOI: 10.1097/MD.0000000000009925