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Tidsskrift For Den Norske Laegeforening... Mar 2021
Topics: Humans; Pain, Postoperative; Palatine Tonsil; Postoperative Hemorrhage
PubMed: 33754674
DOI: 10.4045/tidsskr.21.0127 -
The Malaysian Journal of Pathology Apr 2018Tonsillectomy is among the most commonly performed operations in children. Although follicular lymphoid hyperplasia is usually the main and only pathologic finding at... (Review)
Review
Tonsillectomy is among the most commonly performed operations in children. Although follicular lymphoid hyperplasia is usually the main and only pathologic finding at microscopic examination, a variety of other rare but important pathologic changes may be encountered. This review aims to provide an inclusive practical resource and reference for both training and practising pathologists. It discusses the spectrum of pathologic findings, including both neoplastic and non-neoplastic conditions and provides illustrative images.
Topics: Child; Child, Preschool; Female; Humans; Male; Palatine Tonsil; Tonsillectomy
PubMed: 29704380
DOI: No ID Found -
Acta Bio-medica : Atenei Parmensis Feb 2020Tonsil hypertrophy (TH) and adenoid hypertrophy (AH) are very common in children. Adenoid is visible only by endoscopy. This study investigated the possible relationship...
Tonsil hypertrophy (TH) and adenoid hypertrophy (AH) are very common in children. Adenoid is visible only by endoscopy. This study investigated the possible relationship between the tonsil and adenoid volume and the possible prediction of adenoid size. Globally, 991 children (461 females, 530 males, mean age 6.2 ± 2.3 years), complaining persistent upper airway obstruction, were consecutively visited at an otorhinolaryngological unit. TH was significantly (p<0.0001) associated with AH and tonsil volume predicted adenoid size. This outcome could have relevance in clinical practice as adenoid are evaluable only by endoscopy, so tonsil assessment could mirror adenoid volume.
Topics: Adenoids; Child; Child, Preschool; Endoscopy; Female; Humans; Hypertrophy; Male; Organ Size; Palatine Tonsil; Predictive Value of Tests
PubMed: 32073566
DOI: 10.23750/abm.v91i1-S.9231 -
Laryngo- Rhino- Otologie May 2023The hyperplasia of the lingual tonsil is a rare and at the same time potentially dangerous change in the area of the upper respiratory tract. The pathogenesis of the...
OBJECTIVE
The hyperplasia of the lingual tonsil is a rare and at the same time potentially dangerous change in the area of the upper respiratory tract. The pathogenesis of the lingual tonsillar hyperplasia is still largely unknown. In this study, we investigated if there is a compensatory lingual tonsil hyperplasia after tonsillectomy.
MATERIAL AND METHODS
300 patients were examined consecutively in the ENT clinic of the Hannover Medical School. In the context of indirect laryngoscopy, the lingual tonsil, the visibility of the larynx and its subregions were assessed according to a scheme. The data were then evaluated depending on the status of the palatal tonsils. In addition, the body mass index (BMI) was determined and compared with the results of laryngoscopy.
RESULTS
Out of 300 patients, 89 (29.6%) were in condition after bilateral tonsillectomy. In the total population, a greatly enlarged lingual tonsil was only detectable in 14 cases (4.6%). Of these 14 patients, 4 had a history of tonsillectomy. In patients with severe lingual tonsil hyperplasia the mean BMI was 27.3 compared to 24.4 in patients with a normal lingual tonsil.
CONCLUSION
In our population the incidence of severe lingual tonsil hyperplasia is 4.7%. We couldn't prove s a connection between a condition after tonsillectomy and compensatory lingual hyperplasia statistically. However, there was a significant relationship between BMI and lingual tonsil hyperplasia.
Topics: Humans; Body Mass Index; Hyperplasia; Hypertrophy; Palatine Tonsil; Tonsillectomy
PubMed: 36543221
DOI: 10.1055/a-1887-6352 -
Veterinary Radiology & Ultrasound : the... Jan 2018The palatine tonsil is an uncommon site of oral canine neoplasia. For affected tonsils, squamous cell carcinoma is the most frequent type of neoplasia, followed by...
The palatine tonsil is an uncommon site of oral canine neoplasia. For affected tonsils, squamous cell carcinoma is the most frequent type of neoplasia, followed by melanoma and lymphoma. Computed tomography (CT) is increasingly used for investigation of canine oropharyngeal pathology; however, limited information is available on the CT appearance of tonsillar neoplasms. Objectives of this retrospective descriptive case series were to characterize the CT features of canine tonsillar neoplasia and determine whether specific CT features differentiate nonneoplastic from neoplastic tonsils. Computed tomographic studies of 14 dogs diagnosed with tonsillar neoplasia were retrieved from two referral hospitals and reviewed by two observers. Diagnosis was based on histology or cytology. Carcinoma was diagnosed in 11 dogs, melanoma in two and lymphoma in one dog. Specific CT features of the tonsil and regional lymph nodes did not differentiate neoplastic from nonneoplastic tonsillar diseases, but regional lymph node CT features were useful for diagnosis in some cases. Marked enlargement (width ≥ 18 mm, 12/18), heterogeneity (16/18), and loss of the hypoattenuating hilus (18/18) of the medial retropharyngeal lymph node were common concomitant features of tonsillar neoplasia. The medial retropharyngeal and mandibular lymphadenomegaly was ipsilateral to the neoplastic tonsil in 8/12 and 6/9 dogs, respectively. Five dogs demonstrated little or no enlargement of the tonsil despite the associated metastatic lymphadenomegaly. Tonsillar neoplasia should therefore be considered as a differential diagnosis for dogs with CT evidence of isolated medial retropharyngeal lymphadenomegaly (regardless of normally sized tonsils), or of any enlarged tonsil with no associated lymphadenomegaly.
Topics: Animals; Dog Diseases; Dogs; Female; Male; Palatine Tonsil; Pharyngeal Diseases; Retrospective Studies; Tomography, X-Ray Computed; Tonsillar Neoplasms
PubMed: 28929544
DOI: 10.1111/vru.12561 -
The Tohoku Journal of Experimental... Mar 1975Free amino acids in the tissue of the palatine tonsil and the adenoid were analyzed using a JEOL 6-AS Type Auto-Analyzer, and comparative examination was made on 26...
Free amino acids in the tissue of the palatine tonsil and the adenoid were analyzed using a JEOL 6-AS Type Auto-Analyzer, and comparative examination was made on 26 kinds of amino acids discovered. Of these, 23 amino acids showed significantly high values in the palatine tonsil, but hydroxyproline and tryptophan showed somewhat higher values in the adenoid. These results suggest that the metabolism in the palatine tonsil is more active than in the adenoid.
Topics: Adenoids; Amino Acids; Child; Child, Preschool; Female; Glutamates; Humans; Hydroxyproline; Male; Palatine Tonsil; Serine; Urea
PubMed: 1129773
DOI: 10.1620/tjem.115.259 -
Frontiers in Immunology 2023Although tonsillectomy is performed frequently, the role of palatine tonsils in life long immune protection or tolerance is still debated and the consequences of their...
Although tonsillectomy is performed frequently, the role of palatine tonsils in life long immune protection or tolerance is still debated and the consequences of their removal for the immune system are of general interest. We analysed the tonsillar myeloid compartment in healthy subjects across a wide range of age (64% male; age range: 3 - 85 years) and compared its composition to the peripheral blood. We could observe a strong accumulation of all granulocyte subsets in the aging tonsil, which was most pronounced for basophils and mast cells. On functional level, an increase of CD163 and CD206 expression among monocytes and an increase of neutrophils expressing the inhibitory FcγRIIb correlated with increasing age. While the age-related shift of the leukocyte composition towards monocytes in blood is not reflected in tonsils, the increasing immunoregulatory phenotype of tonsilar monocytes is potentially counteracting the phenomenon of inflammaging at higher age.
Topics: Male; Female; Animals; Palatine Tonsil; Tonsillectomy
PubMed: 37457697
DOI: 10.3389/fimmu.2023.1183212 -
Cells Mar 2020Mesenchymal stromal cells (MSCs) from various sources exhibit different potential for stemness and therapeutic abilities. Recently, we reported a unique MSCs from human...
Mesenchymal stromal cells (MSCs) from various sources exhibit different potential for stemness and therapeutic abilities. Recently, we reported a unique MSCs from human palatine tonsil (TMSCs) and their superior proliferation capacity compared to MSCs from other sources. However, unique characteristics of each MSC are not yet precisely elucidated. We investigated the role of stanniocalcin-1 (STC1), an anti-oxidative hormone, in the functions of TMSCs. We found that STC1 was highly expressed in TMSC compared with MSCs from bone marrow or adipose tissue. The proliferation, senescence and differentiation of TMSCs were assessed after the inhibition of STC1 expression. STC1 inhibition resulted in a significant decrease in the proliferation of TMSCs and did not affect the differentiation potential. To reveal the anti-oxidative ability of STC1 in TMSCs themselves or against other cell types, the generation of mitochondrial reactive oxygen species (ROS) in TMSC or ROS-mediated production of interleukin (IL)-1β from macrophage-like cells were detected. Interestingly, the basal level of ROS generation in TMSCs was significantly elevated after STC1 inhibition. Moreover, down-regulation of STC1 impaired the inhibitory effect of TMSCs on IL-1β production in macrophages. Taken together, these findings indicate that STC1 is highly expressed in TMSCs and plays a critical role in proliferating and ROS-regulatory abilities.
Topics: Cell Proliferation; Glycoproteins; Humans; Mesenchymal Stem Cells; Palatine Tonsil; Reactive Oxygen Species; Transfection
PubMed: 32155780
DOI: 10.3390/cells9030636 -
Brazilian Journal of Otorhinolaryngology 2016Adenotonsillectomy is the most common surgery performed by otolaryngologists in pediatric age, and one of the most frequently asked questions about the postoperative...
INTRODUCTION
Adenotonsillectomy is the most common surgery performed by otolaryngologists in pediatric age, and one of the most frequently asked questions about the postoperative period is whether there is a potential for change in vocal pattern of these children.
OBJECTIVE
To evaluate the impact of adenotonsillectomy in the voice emission pattern of children with hypertrophy of palatine and pharyngeal tonsils.
METHODS
This is a prospective study in which we carried out perceptual auditory assessments and acoustic analysis of 26 children with adenotonsillar hypertrophy at three time points: before surgery, one month and three months after surgery. The following acoustic parameters were estimated using the Praat software: fundamental frequency, jitter, shimmer, and harmonic-noise ratio.
RESULTS
A statistically significant change was found between shimmer and harmonic-noise ratio during vowel /u/ production between the preoperative and 1st month postoperative time points. No significant differences were detected for acoustic parameters between preoperative analysis and that of the 3rd month post-operation.
CONCLUSION
Transient changes in acoustic parameters occur in children with adenotonsillar hypertrophy submitted to adenotonsillectomy, progressing to normalization in the 3rd postoperative month.
Topics: Adenoidectomy; Child; Child, Preschool; Female; Humans; Hypertrophy; Male; Palatine Tonsil; Postoperative Period; Prospective Studies; Speech Acoustics; Tonsillectomy; Voice Quality
PubMed: 26750309
DOI: 10.1016/j.bjorl.2015.11.005 -
Lancet (London, England) Nov 1980
Topics: Anaerobiosis; Bacteria; Child; Humans; Metronidazole; Palatine Tonsil; Streptococcus pyogenes; Tonsillitis; beta-Lactamases
PubMed: 6107605
DOI: 10.1016/s0140-6736(80)92122-4