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Revista Medica de Chile Oct 2019Tridimensional printing is becoming relevant in medicine, specially in surgical and interventional specialties. We review the technical aspects and clinical application... (Review)
Review
Tridimensional printing is becoming relevant in medicine, specially in surgical and interventional specialties. We review the technical aspects and clinical application of airway tridimensional printing. Using this technique, simulation models for bronchoscopy and models for diagnostic and therapeutic procedures such as stent design, tracheal reconstruction and airway models can be created.
Topics: Humans; Models, Anatomic; Printing, Three-Dimensional; Prostheses and Implants; Prosthesis Design; Respiratory System; Simulation Training; Stents; Trachea
PubMed: 32186640
DOI: 10.4067/s0034-98872019001001315 -
Asian Journal of Andrology 2020Since their popularization, genitourinary prosthetics have remained a gold-standard therapy for the treatment of erectile dysfunction and stress urinary incontinence and... (Review)
Review
Since their popularization, genitourinary prosthetics have remained a gold-standard therapy for the treatment of erectile dysfunction and stress urinary incontinence and in cases of testicular loss or dysfunction. They have also represented an area of significant innovation, which has contributed to excellent long-term outcomes. Given this history, the objective of the current review was to provide a 5-10-year outlook on anticipated trends and developments in the field of genitourinary prosthetics. To accomplish this objective, a PubMed and patent search was performed of topics relating to penile and testicular prostheses and urinary sphincters. In regard to penile prostheses, findings demonstrated several new concepts including temperature-sensitive alloys, automated pumps, devices designed specifically for neophalluses, and improved malleable designs. With artificial urinary sphincters, new concepts include the ability to add or remove fluid from an existing system, two-piece systems, and new mechanisms to occlude the urethra. For testicular prosthetics, future implementations may not only better replicate the feel of a biological testicle but also add endocrinological functions. Beyond device innovation, the future of prosthetics is also one of expanding geographic boundaries, which necessitates variable cost modeling and regulatory considerations. Surgical trends are also changing, with a greater emphasis on nonnarcotic, postoperative pain control, outpatient surgeries, and adjunctive techniques to lengthen the penis and address concomitant stress incontinence, among others. Concomitant with device and surgical changes, future considerations also include a greater need for education and training, particularly given the rapid expansion of sexual medicine into developing nations.
Topics: Erectile Dysfunction; Humans; Male; Penile Implantation; Penile Prosthesis; Prostheses and Implants; Prosthesis Design; Prosthesis Implantation; Testicular Diseases; Urinary Incontinence, Stress; Urinary Sphincter, Artificial; Urologic Surgical Procedures, Male
PubMed: 31571642
DOI: 10.4103/aja.aja_103_19 -
The Journal of Thoracic and... Dec 2017
Topics: Humans; Mitral Valve; Prolapse; Prostheses and Implants; Prosthesis Implantation; Tricuspid Valve
PubMed: 28942977
DOI: 10.1016/j.jtcvs.2017.08.084 -
Journal of Orthopaedic Trauma Sep 2010Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently... (Review)
Review
Musculoskeletal infection is a clinical problem with significant direct healthcare costs. The prevalence of infection after closed, elective surgery is frequently estimated to be less than 2%, but in severe injuries, posttraumatic infection rates have been reported as 10% or greater. Although clinical infections are found outside the realm of medical devices, it is clear that the enormous increase of infections associated with the use of implants presents a major challenge worldwide. This review summarizes recent advances in the understanding, diagnosis, and treatment of musculoskeletal infections.
Topics: Animals; Bacterial Infections; Biofilms; Disease Models, Animal; Drug Resistance, Microbial; Host-Pathogen Interactions; Humans; Musculoskeletal Diseases; Prostheses and Implants; Prosthesis-Related Infections; Surgical Wound Infection
PubMed: 20736799
DOI: 10.1097/BOT.0b013e3181eebf12 -
Current Osteoporosis Reports Jun 2018Recently, significant progress has been made in the research related to regenerative medicine. At the same time, biomedical implants in orthopedics and dentistry are... (Review)
Review
PURPOSE OF REVIEW
Recently, significant progress has been made in the research related to regenerative medicine. At the same time, biomedical implants in orthopedics and dentistry are facing many challenges and posing clinical concerns. The purpose of this chapter is to provide an overview of the clinical applications of current regenerative strategies to the fields of dentistry and orthopedic surgery. The main research question in this review is: What are the major advancement strategies in regenerative medicine that can be used for implant research?
RECENT FINDINGS
The implant surfaces can be modified through patient-specific stem cells and plasma coatings, which may provide methods to improve osseointegration and sustainability of the implant. Overall understanding from the review suggesting that the outcome from the studies could lead to identify optimum solutions for many concerns in biomedical implants and even in drug developments as a long-term solution to orthopedic and dental patients.
Topics: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone-Implant Interface; Dental Implants; Hip Prosthesis; Humans; Joint Prosthesis; Knee Prosthesis; Orthopedics; Osseointegration; Osteoarthritis; Prostheses and Implants; Regenerative Medicine; Spondylosis; Stem Cells; Total Disc Replacement
PubMed: 29679306
DOI: 10.1007/s11914-018-0441-0 -
Experimental Neurology Jan 2017Safe and effective neuroprosthetic systems are of great interest to both DARPA and CDRH, due to their innovative nature and their potential to aid severely disabled... (Review)
Review
Safe and effective neuroprosthetic systems are of great interest to both DARPA and CDRH, due to their innovative nature and their potential to aid severely disabled populations. By expanding what is possible in human-device interaction, these devices introduce new potential benefits and risks. Therefore patient input, which is increasingly important in weighing benefits and risks, is particularly relevant for this class of devices. FDA has been a significant contributor to an ongoing stakeholder conversation about the inclusion of the patient voice, working collaboratively to create a new framework for a patient-centered approach to medical device development. This framework is evolving through open dialogue with researcher and patient communities, investment in the science of patient input, and policymaking that is responsive to patient-centered data throughout the total product life cycle. In this commentary, we will discuss recent developments in patient-centered benefit-risk assessment and their relevance to the development of neural prosthetic systems.
Topics: Brain-Computer Interfaces; Device Approval; Disabled Persons; Guidelines as Topic; Humans; Patient Preference; Patient-Centered Care; Prostheses and Implants; Prosthesis Design; Risk Assessment; United States; United States Food and Drug Administration
PubMed: 27456271
DOI: 10.1016/j.expneurol.2016.07.017 -
The Bone & Joint Journal Feb 2021Antibiotic resistance represents a threat to human health. It has been suggested that by 2050, antibiotic-resistant infections could cause ten million deaths each year.... (Review)
Review
Antibiotic resistance represents a threat to human health. It has been suggested that by 2050, antibiotic-resistant infections could cause ten million deaths each year. In orthopaedics, many patients undergoing surgery suffer from complications resulting from implant-associated infection. In these circumstances secondary surgery is usually required and chronic and/or relapsing disease may ensue. The development of effective treatments for antibiotic-resistant infections is needed. Recent evidence shows that bacteriophage (phages; viruses that infect bacteria) therapy may represent a viable and successful solution. In this review, a brief description of bone and joint infection and the nature of bacteriophages is presented, as well as a summary of our current knowledge on the use of bacteriophages in the treatment of bacterial infections. We present contemporary published in vitro and in vivo data as well as data from clinical trials, as they relate to bone and joint infections. We discuss the potential use of bacteriophage therapy in orthopaedic infections. This area of research is beginning to reveal successful results, but mostly in nonorthopaedic fields. We believe that bacteriophage therapy has potential therapeutic value for implant-associated infections in orthopaedics. Cite this article: 2021;103-B(2):234-244.
Topics: Arthritis, Infectious; Bacterial Infections; Bone Diseases, Infectious; Humans; Orthopedic Fixation Devices; Phage Therapy; Prostheses and Implants; Prosthesis-Related Infections; Treatment Outcome
PubMed: 33517726
DOI: 10.1302/0301-620X.103B2.BJJ-2020-0452.R2 -
Clinical Microbiology and Infection :... Dec 2012
Topics: Humans; Orthopedic Procedures; Osteoarthritis; Prostheses and Implants; Prosthesis-Related Infections
PubMed: 23148446
DOI: 10.1111/j.1469-0691.2012.04011.x -
AJNR. American Journal of Neuroradiology Feb 2014Cosmetic rhinoplasty encompasses a diverse group of procedures, including alteration of the radix, nasal dorsum, nasal tip, and nasal base; premaxillary augmentation;... (Review)
Review
Cosmetic rhinoplasty encompasses a diverse group of procedures, including alteration of the radix, nasal dorsum, nasal tip, and nasal base; premaxillary augmentation; septoplasty; and combinations thereof. Similarly, many different types of grafts and alloplastic materials can be used in cosmetic rhinoplasty, such as cartilage, bone, silicone, porous polyethylene, expanded polytetrafluoroethylene, and calcium hydroxylapatite. Complications of rhinoplasty that can be observed on imaging include retained metallic surgical instrument fragments, infection, implant extrusion, nerve impingement by implants, nasal valve collapse, and implant deformity. Knowledge of the basic surgical procedures and potential complications of cosmetic rhinoplasty is important for adequately interpreting postoperative radiologic imaging studies.
Topics: Equipment Failure Analysis; Foreign-Body Reaction; Humans; Paresthesia; Prostheses and Implants; Prosthesis Design; Prosthesis-Related Infections; Radiography; Rhinoplasty; Surgery, Computer-Assisted
PubMed: 23306010
DOI: 10.3174/ajnr.A3443 -
BioMed Research International 2015
Topics: Female; Gynecology; Humans; Legislation as Topic; Male; Prostheses and Implants; Plastic Surgery Procedures; United States; United States Food and Drug Administration; Urology
PubMed: 25984531
DOI: 10.1155/2015/354342