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Diagnostic Microbiology and Infectious... Jan 2021A prolonged incubation time is generally recommended for diagnosing periprosthetic joint infections (PJI). However, in literature, no distinction is made between acute...
INTRODUCTION
A prolonged incubation time is generally recommended for diagnosing periprosthetic joint infections (PJI). However, in literature, no distinction is made between acute and chronic infections.
METHODS
All patients with a PJI that underwent surgical debridement between November 2015 and February 2019 with or without revision of the prosthesis were retrospectively evaluated. Synovial fluid, 5 intraoperative periprosthetic tissue samples, and the sonicated prosthesis were cultured.
RESULTS
Fifty-nine patients were analyzed, including 21 acute PJIs (33 isolates) and 38 chronic PJIs (46 isolates). In acute PJIs, all isolates grew within 5 days, while this took 11 days for chronic PJIs. Sonication fluid showed the shortest time to positivity (78% at day 2) for chronic PJIs, but no difference was observed for acute PJIs compared to tissue cultures.
CONCLUSION
In contrast to cultures from chronic PJIs, acute PJIs do not need a prolonged incubation time and no clear benefit is observed for sonication.
Topics: Arthroplasty; Bacteria; Humans; Infectious Disease Incubation Period; Prostheses and Implants; Prosthesis-Related Infections; Reoperation; Retrospective Studies; Synovial Fluid
PubMed: 33017799
DOI: 10.1016/j.diagmicrobio.2020.115178 -
Asian Journal of Andrology Nov 2011A new type of testicular prosthesis made of silastic with an elliptical shape to mimic a normal testis was developed by our team and submitted for patenting in China....
A new type of testicular prosthesis made of silastic with an elliptical shape to mimic a normal testis was developed by our team and submitted for patenting in China. The prosthesis was produced in different sizes to imitate the normal testis of the patient. To investigate the effects and safety of the testicular prosthesis, 20 patients receiving testicular prosthesis implantation were recruited for this study. Follow-up after 6 months revealed no complications in the patients. All the patients answered that they were satisfied with their body image and the position of the implants, 19 patients were satisfied with the size and 16 patients were satisfied with the weight. These results show that the testicular prosthesis used in this study can meet patient's expectations. Patients undergoing orchiectomy should be offered the option to receive a testicular prosthesis implantation. The dimensions and weight of the available prosthetic implants should be further addressed to improve patient satisfaction.
Topics: Adult; Humans; Male; Patient Satisfaction; Prostheses and Implants; Testis
PubMed: 21927041
DOI: 10.1038/aja.2011.87 -
Neurosurgical Focus Jul 2009Common causes of blindness are diseases that affect the ocular structures, such as glaucoma, retinitis pigmentosa, and macular degeneration, rendering the eyes no longer... (Review)
Review
Common causes of blindness are diseases that affect the ocular structures, such as glaucoma, retinitis pigmentosa, and macular degeneration, rendering the eyes no longer sensitive to light. The visual pathway, however, as a predominantly central structure, is largely spared in these cases. It is thus widely thought that a device-based prosthetic approach to restoration of visual function will be effective and will enjoy similar success as cochlear implants have for restoration of auditory function. In this article the authors review the potential locations for stimulation electrode placement for visual prostheses, assessing the anatomical and functional advantages and disadvantages of each. Of particular interest to the neurosurgical community is placement of deep brain stimulating electrodes in thalamic structures that has shown substantial promise in an animal model. The theory of operation of visual prostheses is discussed, along with a review of the current state of knowledge. Finally, the visual prosthesis is proposed as a model for a general high-fidelity machine-brain interface.
Topics: Animals; Blindness; Deep Brain Stimulation; Electrodes, Implanted; Humans; Models, Animal; Neurosurgical Procedures; Prostheses and Implants; Prosthesis Design; Prosthesis Implantation; Retina; Thalamus; User-Computer Interface; Vision, Ocular; Visual Cortex; Visual Pathways; Visual Perception
PubMed: 19569894
DOI: 10.3171/2009.4.FOCUS0986 -
The Bone & Joint Journal Dec 2016Extendible endoprostheses have been available for more than 30 years and have become more sophisticated with time. The latest generation is 'non-invasive' and can be...
AIMS
Extendible endoprostheses have been available for more than 30 years and have become more sophisticated with time. The latest generation is 'non-invasive' and can be lengthened with an external magnetic force. Early results have shown a worryingly high rate of complications such as infection. This study investigates the incidence of complications and the need for further surgery in a cohort of patients with a non-invasive growing endoprosthesis.
PATIENTS AND METHODS
Between 2003 and June 2014, 50 children (51 prostheses) had a non-invasive growing prosthesis implanted for a primary bone sarcoma. The minimum follow-up was 24 months for those who survived. Their mean age was 10.4 years (6 to 14). The incidence of complications and further surgery was documented.
RESULTS
The mean follow-up was 64 months (20 to 145). The overall survivorship of the patients was 84% at three years and 70% at five years. Revision-free survival was 81.7% at three years and 61.6% at five years with competing risk analysis. Deep infection occurred in 19.6% of implants at a mean of 12.5 months (0 to 55). Other complications were a failure of the lengthening mechanism in five prostheses (9.8%) and breakage of the implant in two (3.9%). Overall, there were 53 additional operations (0 to 5 per patient). A total of seven patients (14%) underwent amputation, three for local recurrence and four for infection. Their mean limb length discrepancy was 4.3 mm (0 to 25) and mean Musculoskeletal Tumor Society Score functional score was 26.5 (18 to 30) at the final follow-up.
CONCLUSIONS
When compared with previously published early results, this mid-term series has shown continued good functional outcomes and compensation for leg-length discrepancy. Infection is still the most common complication: post-operative wound healing problems, central line infection and proximal tibial location are the main risk factors. Cite this article: Bone Joint J 2016;98-B:1697-1703.
Topics: Adolescent; Age Distribution; Bone Lengthening; Bone Neoplasms; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Male; Periprosthetic Fractures; Prostheses and Implants; Prosthesis Design; Prosthesis Failure; Prosthesis Implantation; Prosthesis-Related Infections; Reoperation; Sarcoma; Sex Distribution
PubMed: 27909134
DOI: 10.1302/0301-620X.98B12.BJJ-2016-0467 -
EuroIntervention : Journal of EuroPCR... Nov 2023
Topics: Humans; Transcatheter Aortic Valve Replacement; Heart Valve Prosthesis Implantation; Aortic Valve; Prostheses and Implants; Aortic Valve Stenosis; Heart Valve Prosthesis; Treatment Outcome; Prosthesis Design; Risk Factors
PubMed: 37994100
DOI: 10.4244/EIJ-E-23-00048 -
Journal of Refractive Surgery... Jan 2023
Topics: Humans; Cornea; Prostheses and Implants; Corneal Stroma; Prosthesis Implantation; Keratoconus; Corneal Topography
PubMed: 36630437
DOI: 10.3928/1081597X-20221206-01 -
Medicine Mar 2020Breast loss causes negative influence on women physically, psychologically, and socially. Breast prosthesis can improve patient's figure externally, increase... (Randomized Controlled Trial)
Randomized Controlled Trial
Physical and psychological effects of different temperature-controlled breast prostheses on patients with breast cancer during rehabilitation: a randomized controlled study (CONSORT).
BACKGROUND
Breast loss causes negative influence on women physically, psychologically, and socially. Breast prosthesis can improve patient's figure externally, increase self-confidence, thus improving quality of life (QOL). Prospective study of different breast prostheses has not yet been performed in China. Our objective was to evaluate the QOL of patients wearing different types of breast prostheses and to compare the physical and psychological effects of different temperature-controlled breast prostheses on patients.
METHODS
Thirty patients with breast cancer were recruited through the Yankang E-follow-up Platform at the Department of Breast Surgery of Fudan University, Shanghai Cancer Center and were randomized into either intervention or control group. Random number tables were used in this study for randomization. In the first 6 weeks of the study, self-adhesive breast prostheses and conventional breast prostheses had been used in the intervention and control group, respectively. In the later 6 weeks, the breast prostheses used were switched into another kind. Several dimensional parameters including skin conditions, breast prosthesis knowledge, breast prosthesis knowledge, QOL, and body image were examined by different questionnaires in the end of both 6th and 12th week.
RESULTS
There were no significant difference in QOL and body image between the 2 groups during 6th and 12th week. At the 6th week of the study, patients of the intervention group preferred to the self-adhesive breast prosthesis, indicating that the self-adhesive breast prosthesis seemed more likely to feel like part of their body, while prosthesis cleaning remaining their biggest concern. At the end of 12th week, in comparison with the number at 6th week, more patients in both groups were willing to choose self-adhesive breast prosthesis.
CONCLUSIONS
We conclude that women are satisfied with the temperature-controlled breast prosthesis and are more willing to choose self-adhesive breast prostheses although cleaning remains a problem. In China, patients still lack information about breast prostheses. Therefore, specialist breast nurses should provide comprehensive information about breast prostheses, assist patients in selecting suitable breast prostheses, collect feedback about the prostheses, and reduce each patient's physical and mental discomfort.
Topics: Adult; Body Image; Breast Neoplasms; Cross-Over Studies; Female; Humans; Mastectomy; Middle Aged; Patient Preference; Patient Satisfaction; Prospective Studies; Prostheses and Implants; Quality of Life; Temperature
PubMed: 32221086
DOI: 10.1097/MD.0000000000019616 -
TheScientificWorldJournal Jan 2009We present an overview of the current literature and management techniques for vaginal extrusion or urinary tract erosion of graft materials used in pelvic floor... (Review)
Review
We present an overview of the current literature and management techniques for vaginal extrusion or urinary tract erosion of graft materials used in pelvic floor reconstruction. A MEDLINE search was performed to identify literature pertaining to the incidence and management of vaginal or urinary tract exposure of graft materials commonly used in anti-incontinence and pelvic floor reconstructive procedures. Dependent on the type of mesh material used, a vaginal extrusion rate of up to 77% has been reported. The currently accepted, loosely woven, monofilament type I polypropylene meshes appear to have acceptable lower exposure rates in the range of 1-3% for slings, but with the larger area of mesh used in prolapse repairs, the rate increases to up to 10%. With the current widespread use of graft materials to reinforce pelvic floor reconstructive techniques, it is imperative for surgeons to be familiar with potential complications related to the materials and proper management of these complications. Although it is beginning to appear that the benefit of using some synthetic materials may outweigh the risks, proper management and understanding of the risks is important in order to counsel our patients appropriately and responsibly prior to their surgeries.
Topics: Humans; Materials Testing; Pelvic Floor; Prostheses and Implants; Plastic Surgery Procedures
PubMed: 19151896
DOI: 10.1100/tsw.2009.2 -
Neurosurgical Focus Jul 2009Direct brain control of a prosthetic system is the subject of much popular and scientific news. Neural technology and science have advanced to the point that... (Review)
Review
Direct brain control of a prosthetic system is the subject of much popular and scientific news. Neural technology and science have advanced to the point that proof-of-concept systems exist for cortically-controlled prostheses in rats, monkeys, and even humans. However, realizing the dream of making such technology available to everyone is still far off. Fortunately today there is great public and scientific interest in making this happen, but it will only occur when the functional benefits of such systems outweigh the risks. In this article, the authors briefly summarize the state of the art and then highlight many issues that will directly limit clinical translation, including system durability, system performance, and patient risk. Despite the challenges, scientists and clinicians are in the desirable position of having both public and fiscal support to begin addressing these issues directly. The ultimate challenge now is to determine definitively whether these prosthetic systems will become clinical reality or forever unrealized.
Topics: Cerebral Cortex; Electrodes, Implanted; Ethics, Research; Humans; Man-Machine Systems; Motor Cortex; Paralysis; Prostheses and Implants; Prosthesis Design; Risk Factors; Signal Processing, Computer-Assisted; User-Computer Interface
PubMed: 19569893
DOI: 10.3171/2009.4.FOCUS0987 -
Journal of Thrombosis and Haemostasis :... Jun 2015Blood-contacting medical devices, such as vascular grafts, stents, heart valves, and catheters, are often used to treat cardiovascular diseases. Thrombus formation is a... (Review)
Review
Blood-contacting medical devices, such as vascular grafts, stents, heart valves, and catheters, are often used to treat cardiovascular diseases. Thrombus formation is a common cause of failure of these devices. This study (i) examines the interface between devices and blood, (ii) reviews the pathogenesis of clotting on blood-contacting medical devices, (iii) describes contemporary methods to prevent thrombosis on blood-contacting medical devices, (iv) explains why some anticoagulants are better than others for prevention of thrombosis on medical devices, and (v) identifies future directions in biomaterial research for prevention of thrombosis on blood-contacting medical devices.
Topics: Animals; Anticoagulants; Blood Coagulation; Blood Vessel Prosthesis; Catheter Obstruction; Coated Materials, Biocompatible; Fibrinolytic Agents; Graft Occlusion, Vascular; Heart Valve Prosthesis; Heart-Assist Devices; Humans; Prostheses and Implants; Prosthesis Design; Prosthesis Failure; Stents; Thrombosis; Vascular Access Devices
PubMed: 26149053
DOI: 10.1111/jth.12961