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Journal of Neurophysiology Aug 2020Express saccades are unusually short latency, visually guided saccadic eye movements. They are most commonly observed when the fixation spot disappears at a consistent,...
Express saccades are unusually short latency, visually guided saccadic eye movements. They are most commonly observed when the fixation spot disappears at a consistent, short interval before a target spot appears at a repeated location. The saccade countermanding task includes no fixation-target gap, variable target presentation times, and the requirement to withhold saccades on some trials. These testing conditions should discourage production of express saccades. However, two macaque monkeys performing the saccade countermanding task produced consistent, multimodal distributions of saccadic latencies. These distributions consisted of a longer mode extending from 200 ms to as much as 600 ms after target presentation and another consistently less than 100 ms after target presentation. Simulations revealed that, by varying express saccade production, monkeys could earn more reward. If express saccades were not rewarded, they were rarely produced. The distinct mechanisms producing express and longer saccade latencies were revealed further by the influence of regularities in the duration of the fixation interval preceding target presentation on saccade latency. Temporal expectancy systematically affected the latencies of regular but not of express saccades. This study highlights that cognitive control can integrate information across trials and strategically elicit intermittent very short latency saccades to acquire more reward. A serendipitous discovery that macaque monkeys produce express saccades under conditions that should discourage them reveals how cognitive control can adapt behavior to maximize reward.
Topics: Animals; Anticipation, Psychological; Behavior, Animal; Executive Function; Female; Fixation, Ocular; Macaca mulatta; Macaca radiata; Male; Reward; Saccades; Time Factors; Visual Perception
PubMed: 32667242
DOI: 10.1152/jn.00365.2020 -
Journal of Neurophysiology Mar 2021A fundamental problem in motor control is the coordination of complementary movement types to achieve a common goal. As a common example, humans view moving objects...
A fundamental problem in motor control is the coordination of complementary movement types to achieve a common goal. As a common example, humans view moving objects through coordinated pursuit and saccadic eye movements. Pursuit is initiated and continuously controlled by retinal image velocity. During pursuit, eye position may lag behind the target. This can be compensated by the discrete execution of a catch-up saccade. The decision to trigger a saccade is influenced by both position and velocity errors, and the timing of saccades can be highly variable. The observed distributions of saccade frequency and trigger time remain poorly understood, and this decision process remains imprecisely quantified. Here, we propose a predictive, probabilistic model explaining the decision to trigger saccades during pursuit to foveate moving targets. In this model, expected position error and its associated uncertainty are predicted through Bayesian inference across noisy, delayed sensory observations (Kalman filtering). This probabilistic prediction is used to estimate the confidence that a saccade is needed (quantified through log-probability ratio), triggering a saccade upon accumulating to a fixed threshold. The model qualitatively explains behavioral observations on the frequency and trigger time distributions of saccades during pursuit over a range of target motion trajectories. Furthermore, this model makes novel predictions that saccade decisions are highly sensitive to uncertainty for small predicted position errors, but this influence diminishes as the magnitude of predicted position error increases. We suggest that this predictive, confidence-based decision-making strategy represents a fundamental principle for the probabilistic neural control of coordinated movements. This is the first stochastic dynamical systems model of pursuit-saccade coordination accounting for noise and delays in the sensorimotor system. The model uses Bayesian inference to predictively estimate visual motion, triggering saccades when confidence in predicted position error accumulates to a threshold. This model explains saccade frequency and trigger time distributions across target trajectories and makes novel predictions about the influence of sensory uncertainty in saccade decisions during pursuit.
Topics: Bayes Theorem; Decision Making; Forecasting; Humans; Models, Neurological; Motion Perception; Photic Stimulation; Pursuit, Smooth; Saccades; Stochastic Processes
PubMed: 33356899
DOI: 10.1152/jn.00492.2019 -
Philosophical Transactions of the Royal... Feb 2011Perceptual phenomena that occur around the time of a saccade, such as peri-saccadic mislocalization or saccadic suppression of displacement, have often been linked to... (Review)
Review
Perceptual phenomena that occur around the time of a saccade, such as peri-saccadic mislocalization or saccadic suppression of displacement, have often been linked to mechanisms of spatial stability. These phenomena are usually regarded as errors in processes of trans-saccadic spatial transformations and they provide important tools to study these processes. However, a true understanding of the underlying brain processes that participate in the preparation for a saccade and in the transfer of information across it requires a closer, more quantitative approach that links different perceptual phenomena with each other and with the functional requirements of ensuring spatial stability. We review a number of computational models of peri-saccadic spatial perception that provide steps in that direction. Although most models are concerned with only specific phenomena, some generalization and interconnection between them can be obtained from a comparison. Our analysis shows how different perceptual effects can coherently be brought together and linked back to neuronal mechanisms on the way to explaining vision across saccades.
Topics: Humans; Models, Neurological; Photic Stimulation; Saccades; Space Perception; Visual Perception
PubMed: 21242143
DOI: 10.1098/rstb.2010.0229 -
Vision Research Feb 2018Previous research on the spatiotemporal dynamics of exogenous and endogenous attentional allocation during saccade preparation yielded conflicting results. We...
Previous research on the spatiotemporal dynamics of exogenous and endogenous attentional allocation during saccade preparation yielded conflicting results. We hypothesize that this can be explained by the cueing type used to orient attention in a perceptual task. We investigated the time-course of attentional allocation as a function of cueing type (central vs peripheral), spatial congruency of the cued perceptual and saccade task locations, and cue validity in a dual-task paradigm. Participants performed a visual discrimination task during saccade preparation. We found that central and peripheral cues differentially affected the time-course of attentional allocation depending on spatial congruency and cue validity. Peripheral cues quickly and transiently oriented attention to the cued location. In the congruent condition, attention was maintained by the pre-saccadic attention shift, but declined in the spatially incongruent condition. Central cues slowly oriented attention to the cued location. In the congruent condition, attention was boosted by the pre-saccadic attention shift compared to a slower increase in the spatially incongruent condition. The pre-saccadic attention shift - the automatic and obligatory shift of attention to the saccade target - observed in the invalid spatially incongruent condition was not differentially affected by the cueing type orienting attention away from it. Our results suggest that exogenous and endogenous attention is dynamically and flexibly allocated to cued locations during saccade preparation while pre-saccadic attentional resources are progressively shifted to the saccade target irrespective of the cueing type. We argue that attentional selection for perception represents a partially independent process in contrast to the pre-saccadic attention shift.
Topics: Adult; Analysis of Variance; Attention; Cues; Discrimination, Psychological; Female; Humans; Male; Photic Stimulation; Reaction Time; Saccades; Visual Fields; Visual Perception; Young Adult
PubMed: 29262304
DOI: 10.1016/j.visres.2017.12.002 -
Vision Research Aug 2024Visual attention is typically shifted toward the targets of upcoming saccadic eye movements. This observation is commonly interpreted in terms of an obligatory coupling...
Visual attention is typically shifted toward the targets of upcoming saccadic eye movements. This observation is commonly interpreted in terms of an obligatory coupling between attentional selection and oculomotor programming. Here, we investigated whether this coupling is facilitated by a habitual expectation of spatial congruence between visual and motor targets. To this end, we conducted a dual-task (i.e., concurrent saccade task and visual discrimination task) experiment in which male and female participants were trained to either anticipate spatial congruence or incongruence between a saccade target and an attention probe stimulus. To assess training-induced effects of expectation on premotor attention allocation, participants subsequently completed a test phase in which the attention probe position was randomized. Results revealed that discrimination performance was systematically biased toward the expected attention probe position, irrespective of whether this position matched the saccade target or not. Overall, our findings demonstrate that visual attention can be substantially decoupled from ongoing oculomotor programming and suggest an important role of habitual expectations in the attention-action coupling.
Topics: Humans; Saccades; Attention; Male; Female; Young Adult; Adult; Visual Perception; Photic Stimulation; Reaction Time; Analysis of Variance
PubMed: 38744033
DOI: 10.1016/j.visres.2024.108424 -
Current Biology : CB Mar 2022Neurons governing saccadic eye movements typically multiplex sensory, cognitive, and movement-related signals. How is a reliable 'go' signal extracted from this mixture?...
Neurons governing saccadic eye movements typically multiplex sensory, cognitive, and movement-related signals. How is a reliable 'go' signal extracted from this mixture? A new study reveals that saccade initiation is gated by the temporal stability of rising population activity.
Topics: Movement; Neurons; Saccades
PubMed: 35349819
DOI: 10.1016/j.cub.2022.02.042 -
Proceedings of the National Academy of... Apr 2020Most people easily learn to recognize new faces and places, and with more extensive practice they can become experts at visual tasks as complex as radiological diagnosis...
Most people easily learn to recognize new faces and places, and with more extensive practice they can become experts at visual tasks as complex as radiological diagnosis and action video games. Such perceptual plasticity has been thoroughly studied in the context of training paradigms that require constant fixation. In contrast, when observers learn under more natural conditions, they make frequent saccadic eye movements. Here we show that such eye movements can play an important role in visual learning. Observers performed a task in which they executed a saccade while discriminating the motion of a cued visual stimulus. Additional stimuli, presented simultaneously with the cued one, permitted an assessment of the perceptual integration of information across visual space. Consistent with previous results on perisaccadic remapping [M. Szinte, D. Jonikaitis, M. Rolfs, P. Cavanagh, H. Deubel, 116, 1592-1602 (2016)], most observers preferentially integrated information from locations representing the presaccadic and postsaccadic retinal positions of the cue. With extensive training on the saccade task, these observers gradually acquired the ability to perform similar motion integration without making eye movements. Importantly, the newly acquired pattern of spatial integration was determined by the metrics of the saccades made during training. These results suggest that oculomotor influences on visual processing, long thought to subserve the function of perceptual stability, also play a role in visual plasticity.
Topics: Adult; Cues; Female; Humans; Male; Photic Stimulation; Saccades; Spatial Learning; Visual Perception; Young Adult
PubMed: 32209663
DOI: 10.1073/pnas.1913851117 -
Scientific Reports May 2023The accuracy of saccadic eye movements is maintained by saccadic adaptation, a learning mechanism that is proposed to rely on visual prediction error, i.e., a mismatch...
The accuracy of saccadic eye movements is maintained by saccadic adaptation, a learning mechanism that is proposed to rely on visual prediction error, i.e., a mismatch between the pre-saccadically predicted and post-saccadically experienced position of the saccade target. However, recent research indicates that saccadic adaptation might be driven by postdictive motor error, i.e., a retrospective estimation of the pre-saccadic target position based on the post-saccadic image. We investigated whether oculomotor behavior can be adapted based on post-saccadic target information alone. We measured eye movements and localization judgements as participants aimed saccades at an initially invisible target, which was always shown only after the saccade. Each such trial was followed by either a pre- or a post-saccadic localization trial. The target position was fixed for the first 100 trials of the experiment and, during the following 200 trials, successively shifted inward or outward. Saccade amplitude and the pre- and post-saccadic localization judgements adjusted to the changing target position. Our results suggest that post-saccadic information is sufficient to induce error-reducing adaptive changes in saccade amplitude and target localization, possibly reflecting continuous updating of the estimated pre-saccadic target location driven by postdictive motor error.
Topics: Humans; Saccades; Retrospective Studies; Eye Movements; Acclimatization; Judgment
PubMed: 37221275
DOI: 10.1038/s41598-023-35434-8 -
Vision Research Nov 2018Traditional perceptual learning protocols rely almost exclusively on long periods of uninterrupted fixation. Taking a first step towards understanding perceptual...
Traditional perceptual learning protocols rely almost exclusively on long periods of uninterrupted fixation. Taking a first step towards understanding perceptual learning in natural vision, we had observers report the orientation of a briefly flashed stimulus (clockwise or counterclockwise from a reference orientation) presented strictly during saccade preparation at a location offset from the saccade target. For each observer, the saccade direction, stimulus location, and orientation remained the same throughout training. Subsequently, we assessed performance during fixation in three transfer sessions, either at the trained or at an untrained location, and either using an untrained (Experiment 1) or the trained (Experiment 2) stimulus orientation. We modeled the evolution of contrast thresholds (i.e., the stimulus contrast necessary to discriminate its orientation correctly 75% of the time) as an exponential learning curve, and quantified departures from this curve in transfer sessions using two new, complementary measures of transfer costs (i.e., performance decrements after the transition into the Transfer phase). We observed robust perceptual learning and associated transfer costs for untrained locations and orientations. We also assessed if spatial transfer costs were reduced for the remapped location of the pre-saccadic stimulus-the location the stimulus would have had (but never had) after the saccade. Although the pattern of results at that location differed somewhat from that at the control location, we found no clear evidence for perceptual learning at remapped locations. Using novel, model-based ways to assess learning and transfer costs, our results show that location and feature specificity, hallmarks of perceptual learning, subsist if the target stimulus is presented strictly during saccade preparation throughout training.
Topics: Adolescent; Adult; Attention; Female; Fixation, Ocular; Humans; Learning; Male; Reaction Time; Saccades; Visual Perception; Young Adult
PubMed: 29277450
DOI: 10.1016/j.visres.2017.11.009 -
Journal of Vision Mar 2019Recent studies have demonstrated that saccadic reaction times (SRTs) are influenced by the temporal regularities of dynamic environments (Vullings & Madelain, 2018)....
Recent studies have demonstrated that saccadic reaction times (SRTs) are influenced by the temporal regularities of dynamic environments (Vullings & Madelain, 2018). Here, we ask whether discriminative control (i.e., the possibility to use external stimuli signaling the future state of the environment) of latencies in a search task might be established using reinforcement contingencies. Eight participants made saccades within 80-750 ms toward a target displayed among distractors. We constructed two latency classes, "short" and "long," using the first and last quartiles of the individual baseline distributions. We then used a latency-contingent display paradigm in which finding the visual target among other items was made contingent upon specific SRTs. For a first group, the postsaccadic target was displayed only following short latencies with leftward saccades, and following long latencies with rightward saccades. The opposite was true for a second group. When short- and long-latency saccades were reinforced (i.e., the target was displayed) depending on the saccade direction, median latencies differed by 74 ms on average (all outside the 98% null hypothesis confidence intervals). Posttraining, in the absence of reinforcement, we still observed strong differences in latency distributions, averaging 64 ms for leftward versus rightward saccades. Our results demonstrate the discriminative control of SRTs, further supporting the effects of reinforcement learning for saccade. This study reveals that saccade triggering is finely controlled by learned temporal and spatial properties of the environment using predictive mechanisms.
Topics: Adolescent; Adult; Female; Humans; Learning; Male; Photic Stimulation; Reaction Time; Reinforcement, Psychology; Saccades; Young Adult
PubMed: 30924844
DOI: 10.1167/19.3.16