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Andes Pediatrica : Revista Chilena de... Dec 2021Children with better motor skills tend to develop more positive peer relationships. However, there is little information about the relationship between motor skills and...
INTRODUCTION
Children with better motor skills tend to develop more positive peer relationships. However, there is little information about the relationship between motor skills and the five sociometric status groups, as well as how much it interferes with self-perception of social status.
OBJECTIVE
To analyze the as sociation of low motor skills with sociometric status and perceived social status in students aged 7 to 10 years.
SUBJECTS AND METHOD
Cross-sectional, descriptive study with convenience sampling. Parti cipated in the study children in public schools from Florianopolis, Brazil. Children with disabilities and those who changed schools during the school year were excluded. Motor skills were evaluated by the Movement Assessment Battery for Children (MABC-2), validated for this population. Movement skills were considered low when they were below the 15th percentile. Sociometric Status was assessed using the Subjective Scale of Social Status in the Classroom, according to the sociometric method, and the Perceived Social Status by the MacArthur Scale of Subjective Social Status, classifying chil dren into five groups. Multinominal logistic regression analysis was performed.
RESULTS
439 children participated (242 girls and 197 boys), with a median age of 8.94 ± 1.03. Participants classified as rejec ted, neglected, and controversial, regarding sociometric status, were 5.01, 2.40, and 2.86, respectively, more likely to present low motor skills when compared with the average group. Regarding perceived social status, there were no significant differences.
CONCLUSION
The difficulties found in children with low motor skills go beyond the motor domain, extending to social relationships.
Topics: Child; Cross-Sectional Studies; Female; Humans; Male; Motor Skills; Peer Group; Social Status; Sociometric Techniques
PubMed: 35506797
DOI: 10.32641/andespediatr.v92i6.3537 -
Seizure Aug 2019Hashimoto's encephalopathy is a non-infectious, probably autoimmune encephalitis, characterized by varied signs coupled with elevated levels of anti-thyroid antibodies... (Review)
Review
Hashimoto's encephalopathy is a non-infectious, probably autoimmune encephalitis, characterized by varied signs coupled with elevated levels of anti-thyroid antibodies and, often, good response to corticosteroid therapy. Seizures, namely focal and generalized tonic-clonic seizures, myoclonus, and status epilepticus, are frequent manifestations of Hashimoto's encephalopathy. Typically, seizures in these patients respond poorly to anti-epileptic drugs. Although cases of Hashimoto's encephalopathy with status epilepticus have been reported in literature, they vary in demographic, clinical, and treatment characteristics. We could not identify any systematic review summarizing the evidence in regard to factors predicting the occurrence of status epilepticus in Hashimoto's encephalopathy and the responsiveness of status epilepticus to anti-epileptic drugs, steroids and other immunomodulatory medication. Therefore, we performed an extensive review of the literature to identify and compare Hashimoto's encephalopathy patients presenting with and without status epilepticus. In 31 patients with status epilepticus and 104 patients without status epilepticus, thyroid status, anti-thyroid antibodies, cerebrospinal fluid analysis, brain MRI/CT/SPECT scan did not predict occurrence of status epilepticus of variable phenomenology. Status epilepticus did not respond to anti-epileptic drugs but completely remitted under steroid treatment, alone or in combination with other immunomodulatory medication, in about three quarter of patients. Generalized convulsive status epilepticus might be a factor negatively influencing outcome.
Topics: Adult; Encephalitis; Female; Hashimoto Disease; Humans; Status Epilepticus
PubMed: 31228700
DOI: 10.1016/j.seizure.2019.06.020 -
International Journal of Environmental... Apr 2022Fertility, social status, and social trust are main social choice behaviors of Chinese farmers. This paper adopts the childbearing-value logic to establish a theoretical...
Fertility, social status, and social trust are main social choice behaviors of Chinese farmers. This paper adopts the childbearing-value logic to establish a theoretical model of farmers' childbearing-social status-social trust choices to examine the influence of farmers' childbearing and social status on farmers' social trust. The theoretical model showed that farmers will rationally choose the number of children to bear, emotional value, social value, economic value, social status, and social trust. The fertility of farmers' children is actually a trade-off between quantity and value, and the fertility behavior affects social status through the direct mechanism of the number of children and the value of the adjustment mechanism, and together with the social status, through the direct mechanism, the adjustment mechanism of the number of children, the intermediate mechanism of social status, and the mixed adjustment mechanism. Asymmetry affects social trust equilibrium. Empirical research based on the CFPS (China Family Panel Studies) data in 2018 showed that farmers' children quantity primarily inhibits, through the adjustment mechanism of children's value-social status, social status and social trust; it exerts no direct impact or mediating effect on the social status. The economic value of children does not affect the social status, but it affects social trust through a positive child quantity adjustment mechanism, a negative social status mediation mechanism, and a negative mixed mediation mechanism. The social value of children affects social trust by the positive direct mechanism and the negative children quantity adjustment mechanism, as well as social trust by the negative direct mechanism, children quantity adjustment mechanism, children quantity-social status mixed adjustment mediating mechanism, and the positive social status-mediated mechanism. The emotional value of children affects the social status through the positive direct mechanism, as well as social trust through the positive direct mechanism, social status-mediated mechanism, and negative child quantity adjustment mechanism, and negative mixed mediation mechanism. Furthermore, social status positively impacts social trust rather than a symmetric transmission of the mediating effect of children's value and the quantity adjustment effect of children's value. However, no mediating effect of social trust was observed on children quantity. Social development leads to structural changes in the fertility value of farmers' children, which makes farmers prefer their children's social and economic value, exerting a complex impact on their own social status and social trust.
Topics: Agriculture; Child; China; Farmers; Fertility; Humans; Social Status; Trust
PubMed: 35457627
DOI: 10.3390/ijerph19084759 -
Ugeskrift For Laeger Feb 2023Non-convulsive status epilepticus (NCSE) is a rare complication to electroconvulsive therapy (ECT). This case report presents a 28-year-old female with schizophrenia in...
Non-convulsive status epilepticus (NCSE) is a rare complication to electroconvulsive therapy (ECT). This case report presents a 28-year-old female with schizophrenia in clozapine treatment developing NCSE twice after two different series of ECT treatment. NCSE should be suspected in patients with impairment of consciousness after ECT and requires confirmation with electroencephalogram. Although NCSE is described after ECT, the diagnosis always necessitates thorough screening for other potential underlying causes.
Topics: Female; Humans; Adult; Electroconvulsive Therapy; Status Epilepticus; Electroencephalography; Consciousness
PubMed: 36896614
DOI: No ID Found -
Epilepsia Sep 2013MicroRNAs are an important class of noncoding RNA, which function as posttranscriptional regulators of protein levels within cells. Emerging work has revealed that... (Review)
Review
MicroRNAs are an important class of noncoding RNA, which function as posttranscriptional regulators of protein levels within cells. Emerging work has revealed that status epilepticus produces select changes to microRNA levels within the brain, which may impact levels of proteins involved in neuronal structure and excitability, gliosis, inflammation, and apoptosis. Animal studies show that targeting microRNAs using locked nucleic acid-modified oligonucleotides ("antagomirs") can have potent effects on status epilepticus, seizure-induced neuronal death, and the later emergence of recurrent spontaneous seizures. Accordingly, microRNA-based therapeutics may have potential as a future treatment of status epilepticus.
Topics: Animals; Cell Death; Hippocampus; Humans; MicroRNAs; Neurons; Status Epilepticus
PubMed: 24001063
DOI: 10.1111/epi.12267 -
Journal of Clinical Medicine Apr 2016Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early,... (Review)
Review
Status epilepticus is the most severe form of epilepsy, with a high mortality rate and high health care costs. Status epilepticus is divided into four stages: early, established, refractory, and super-refractory. While initial treatment with benzodiazepines has become standard of care for early status epilepticus, treatment after benzodiazepine failure (established status epilepticus (ESE)) is incompletely studied. Effective treatment of ESE is critical as morbidity and mortality increases dramatically the longer convulsive status epilepticus persists. Phenytoin/fosphenytoin, valproic acid, levetiracetam, phenobarbital, and lacosamide are the most frequently prescribed antiseizure medications for treatment of ESE. To date there are no class 1 data to support pharmacologic recommendations of one agent over another. We review each of these medications, their pharmacology, the scientific evidence in support and against each in the available literature, adverse effects and safety profiles, dosing recommendations, and limitations of the available evidence. We also discuss future directions including the established status epilepticus treatment trial (ESETT). Substantial further research is urgently needed to identify these patients (particularly those with non-convulsive status epilepticus), elucidate the most efficacious antiseizure treatment with head-to-head randomized prospective trials, and determine whether this differs for convulsive vs. non-convulsive ESE.
PubMed: 27120626
DOI: 10.3390/jcm5050049 -
Epilepsia Feb 2010Nonconvulsive status epilepticus (NCSE) in a comatose patient cannot be diagnosed without electroencephalography (EEG). In many advanced coma stages, the EEG exhibits... (Comparative Study)
Comparative Study Review
Nonconvulsive status epilepticus (NCSE) in a comatose patient cannot be diagnosed without electroencephalography (EEG). In many advanced coma stages, the EEG exhibits continuous or periodic EEG abnormalities, but their causal role in coma remains unclear in many cases. To date there is no consensus on whether to treat NCSE in a comatose patient in order to improve the outcome or to retract from treatment, as these EEG patterns might reflect the end stages of a dying brain. On the basis of EEG, NCSE in comatose patients may be classified as generalized or lateralized. This review aims to summarize the ongoing debate of NCSE and coma and to critically reassess the available literature on coma with epileptiform EEG pattern and its prognostic and therapeutic implications. The authors suggest distinguishing NCSE proper and comatose NCSE, which includes coma with continuous lateralized discharges or generalized epileptiform discharges (coma-LED, coma-GED). Although NCSE proper is accompanied by clinical symptoms suggestive of status epilepticus and mild impairment of consciousness, such as in absence status or complex focal status epilepticus, coma-LED and coma-GED represent deep coma of various etiology without any clinical motor signs of status epilepticus but with characteristic epileptiform EEG pattern. Hence coma-LED and coma-GED can be diagnosed with EEG only. Subtle or stuporous status epilepticus and epilepsia partialis continua-like symptoms in severe acute central nervous system (CNS) disorders represent the borderland in this biologic continuum between NCSE proper and comatose NCSE (coma-LED/GED). This pragmatic differentiation could act as a starting point to solve terminologic and factual confusion.
Topics: Adult; Aged; Brain; Central Nervous System Diseases; Coma; Comorbidity; Diagnosis, Differential; Electroencephalography; Epilepsy, Generalized; Female; Functional Laterality; Humans; Male; Middle Aged; Prognosis; Status Epilepticus; Terminology as Topic; Unconsciousness
PubMed: 19744116
DOI: 10.1111/j.1528-1167.2009.02297.x -
SSM - Population Health Mar 2023Previous research on pre-COVID-19 pandemic rising White mortality in the United States suggests that White Americans' perceived decline in relative group status may have... (Review)
Review
Previous research on pre-COVID-19 pandemic rising White mortality in the United States suggests that White Americans' perceived decline in relative group status may have influenced worsening mortality. In conjunction with other social and economic indicators, social status threat is one determinant of this population-level health shift, yet it is unclear perceptions of status threat shape individual health outcomes. Because of this, we sought to identify and synthesize research studies across disciplines that broadly explored how perceived threats to White Americans' social status affect their health. Our research objectives were to (1) examine how status threat (and related constructs) have been measured across the health and social sciences, (2) determine which health outcomes and behaviors are related to status threat, and (3) identify gaps in the existing knowledge base. We systematically searched six multidisciplinary databases. Only 12 studies met inclusion criteria, suggesting that status threat and Whites' health is an understudied topic that warrants continued investigation. Furthermore, there was inconsistency in how threats to status were measured and conceptualized across disciplines. Threat-related indicators evaluated changes in Democratic or Republican vote share, perceived racial treatment, financial status, personal identification with political party affiliation, perceptions of hypothetical "majority-minority" population shifts, racial awareness, and subjective social status. Studies primarily relied on self-rated measures of overall health, mental health status, and social determinants of health. Consequently, there is a gap in the literature concerning which specific health outcomes (besides mortality) are directly affected by status threat. Overall, included studies demonstrated that Whites' can experience negative health effects when they perceive threats in societal conditions, within their interpersonal social experiences, or related to their individual social standing. Moving forward, researchers should consider how Whites' beliefs about their position within social hierarchies potentially affect individual and group-level health outcomes.
PubMed: 36605332
DOI: 10.1016/j.ssmph.2022.101326 -
Journal of Clinical Neurophysiology :... Dec 2015Electrographic status epilepticus and myoclonus represent frequent findings in patients surviving cardiac arrest; both features have been related to poor clinical... (Review)
Review
Electrographic status epilepticus and myoclonus represent frequent findings in patients surviving cardiac arrest; both features have been related to poor clinical outcome. Recent data have outlined that status epilepticus appearing during therapeutic hypothermia and sedation is practically and invariably related to a fatal issue, as opposed to some patients presenting status epilepticus and/or myoclonus after return to normothermic conditions. Although it seems reasonable to give a chance of awakening to the latter patients by administering consequent antiepileptic treatment, especially if other favorable prognostic markers are observed, an aggressive treatment of status epilepticus arising during hypothermia seems futile in view of the existing evidence.
Topics: Anticonvulsants; Humans; Hypothermia, Induced; Status Epilepticus
PubMed: 26629752
DOI: 10.1097/WNP.0000000000000208