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QJM : Monthly Journal of the... Jul 2023
Topics: Humans; Tracheal Neoplasms; Leiomyoma
PubMed: 36944268
DOI: 10.1093/qjmed/hcad044 -
Current Opinion in Pulmonary Medicine Jul 2019This article provides the most recent literature and experienced guidance about diagnosis and management of tracheal tumors, including future directions. (Review)
Review
PURPOSE OF REVIEW
This article provides the most recent literature and experienced guidance about diagnosis and management of tracheal tumors, including future directions.
RECENT FINDINGS
Tracheal tumors are challenging to diagnose given their nonspecific and late-onset symptoms. Critical airway obstruction is the most feared complication. The cornerstone in management of them is surgical resection whenever is possible. Different diagnostic tests (i.e., imaging and bronchoscopy) help in the assessment of resectability. Alternative management including interventional bronchoscopic techniques can be offered to patients who are not suitable for surgical resection. Radiation and chemotherapy can also be used as adjuvant, neoadjuvant or sole treatment in malignant tumors. Recent advances in tracheal transplantation and bioengineering with tracheal reconstruction have shown a new direction in the management of these tumors. All these topics will be discussed in this article.
SUMMARY
Despite advances in diagnostic and therapeutic techniques, tracheal tumors are still a medical challenge. Although studies are still trying to find the best surgical techniques as well as the role for chemotherapy and radiation, most recent studies are addressing tracheal reconstruction and transplantation as the new horizon for management.
Topics: Humans; Patient Care Management; Practice Guidelines as Topic; Tracheal Neoplasms; Treatment Outcome
PubMed: 30973357
DOI: 10.1097/MCP.0000000000000585 -
Head & Neck Surgery 1981Sixty-three patients with primary tracheal tumours were seen in a 15-year period. The most common lesion was squamous-cell carcinoma, the next most common lesion was...
Sixty-three patients with primary tracheal tumours were seen in a 15-year period. The most common lesion was squamous-cell carcinoma, the next most common lesion was adenoid cystic carcinoma, and the remaining lesions were a variety of malignant and benign lesions. There were 3 carcinoid tumors in the group. Twenty-four cylindrical resections of the trachea, 2 lateral resections of the trachea, and 10 carinal reconstructions were performed. The balance of the patients seen in this period of time were not amenable to single-stage reconstruction and were managed by staged procedures, by irradiation, or by no treatment at all. Twenty-eight of the patients in the group with resections had primary tumors and 8 had secondary tumors. Secondary tumors included carcinoma of the thyroid, carcinoma of the esophagus, and recurrent carcinoid tumor in the left main bronchus. Although the numbers in any group are small and the period of follow-up not very long, indications are that surgical removal of squamous-cell carcinoma and adenoid cystic carcinoma of the trachea, usually with adjunctive irradiation, provides good palliation or the possibility of cure. Resection of benign primary tumors and low-grade malignant tumors resulted in excellent palliation and usually cure. Resection of selected secondary tumors did not offer much prospect for cure but did provide long-term palliation.
Topics: Anesthesia; Humans; Methods; Postoperative Complications; Trachea; Tracheal Neoplasms
PubMed: 7287446
DOI: 10.1002/hed.2890040103 -
Acta Oto-rhino-laryngologica Belgica 1998The case of a 76 year old man with a progressive upper respiratory distress due to a chondroma of the trachea is reported which necessitated a segmental tracheal... (Review)
Review
The case of a 76 year old man with a progressive upper respiratory distress due to a chondroma of the trachea is reported which necessitated a segmental tracheal resection with end-to-end anastomosis and restoration of the initial tracheal lumen. This case report is illustrative of a rare benign disease (10 cases described till today) originating from the cartilaginous rings of the trachea. The tumor usually appears as an upper airway obstructing syndrome and endoscopy is essential for establishing the diagnosis. Laser resection can be recommended for the treatment of limited lesions, whereas tracheal resection with end-to-end anastomosis is recommended for more advanced chondroma because it is prone to local recurrence and potentially exposed to malignant transformation into chondrosarcoma.
Topics: Aged; Chondroma; Humans; Intubation, Intratracheal; Male; Stents; Trachea; Tracheal Neoplasms
PubMed: 9810461
DOI: No ID Found -
American Journal of Respiratory and... Aug 2020
Topics: Aged, 80 and over; Female; Humans; Papilloma; Tracheal Neoplasms
PubMed: 32352835
DOI: 10.1164/rccm.201911-2147IM -
Thorax Jul 1993
Topics: Humans; Tracheal Neoplasms
PubMed: 8153911
DOI: 10.1136/thx.48.7.681 -
The Annals of Thoracic Surgery Feb 2012Primary tracheal tumors are rare. Approximately 1% of them are leiomyoma. Given the rarity of these lesions, optimal management has not been defined. Bronchoscopic,...
Primary tracheal tumors are rare. Approximately 1% of them are leiomyoma. Given the rarity of these lesions, optimal management has not been defined. Bronchoscopic, local surgical excision and partial tracheal resection have all been described. One report of recurrence after resection has been published. The incidence of recurrence following local excision is unknown. We report a case of an incidental tracheal leiomyoma diagnosed and treated with a combined approach.
Topics: Adult; Asthma, Exercise-Induced; Bronchoscopy; Humans; Incidental Findings; Leiomyoma; Male; Shoulder Injuries; Sternotomy; Tomography, X-Ray Computed; Tracheal Neoplasms
PubMed: 22269742
DOI: 10.1016/j.athoracsur.2011.07.022 -
Respiration; International Review of... 2019We describe an exceptionally rare case of a male patient with newly diagnosed advanced human immunodeficiency virus (HIV) infection, who presented with a plasmablastic... (Review)
Review
We describe an exceptionally rare case of a male patient with newly diagnosed advanced human immunodeficiency virus (HIV) infection, who presented with a plasmablastic lymphoma involving the right maxillary alveolar ridge with associated cervical lymphadenopathy. On a staging positron emission tomography computed tomography (PET-CT) scan, he was incidentally found to have an endotracheal tumour involving the anterolateral aspect of the mid-trachea. The tumour appeared to be well-vascularised at bronchoscopy and was confirmed as well-differentiated plasmablastic lymphoma. Plasmablastic lymphoma is a rare form of non-Hodgkin lymphoma and is associated with HIV. Tracheal involvement to the extent seen in our patient is exceptionally rare, and, to the best of our knowledge, has never been described.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biopsy, Needle; Bronchoscopy; Combined Modality Therapy; Follow-Up Studies; HIV Infections; Humans; Immunohistochemistry; Male; Neoplasm Invasiveness; Neoplasm Staging; Plasmablastic Lymphoma; Positron Emission Tomography Computed Tomography; Radiotherapy, Adjuvant; Rare Diseases; Tracheal Neoplasms; Treatment Outcome
PubMed: 31634891
DOI: 10.1159/000503586 -
The Journal of Pediatrics Jun 2016
Topics: Histiocytoma, Benign Fibrous; Humans; Infant; Male; Tomography, X-Ray Computed; Tracheal Neoplasms
PubMed: 27056452
DOI: 10.1016/j.jpeds.2016.03.017 -
Journal of the American Veterinary... May 2017
Topics: Aging; Animals; Dog Diseases; Dogs; Male; Plasmacytoma; Tracheal Neoplasms
PubMed: 28414594
DOI: 10.2460/javma.250.9.993