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Advances in Parasitology 2018Climate change is expected to impact across every domain of society, including health. The majority of the world's population is susceptible to pathological, infectious... (Review)
Review
Climate change is expected to impact across every domain of society, including health. The majority of the world's population is susceptible to pathological, infectious disease whose life cycles are sensitive to environmental factors across different physical phases including air, water and soil. Nearly all so-called neglected tropical diseases (NTDs) fall into this category, meaning that future geographic patterns of transmission of dozens of infections are likely to be affected by climate change over the short (seasonal), medium (annual) and long (decadal) term. This review offers an introduction into the terms and processes deployed in modelling climate change and reviews the state of the art in terms of research into how climate change may affect future transmission of NTDs. The 34 infections included in this chapter are drawn from the WHO NTD list and the WHO blueprint list of priority diseases. For the majority of infections, some evidence is available of which environmental factors contribute to the population biology of parasites, vectors and zoonotic hosts. There is a general paucity of published research on the potential effects of decadal climate change, with some exceptions, mainly in vector-borne diseases.
Topics: Animals; Climate Change; Humans; Neglected Diseases; Tropical Climate; Tropical Medicine
PubMed: 29753342
DOI: 10.1016/bs.apar.2018.02.001 -
Infectious Diseases of Poverty Jan 2020Neglected tropical diseases (NTDs) have long been overlooked in the global health agenda. They are intimately related to poverty, cause important local burdens of... (Review)
Review
BACKGROUND
Neglected tropical diseases (NTDs) have long been overlooked in the global health agenda. They are intimately related to poverty, cause important local burdens of disease, but individually do not represent global priorities. Yet, NTDs were estimated to affect close to 2 billion people at the turn of the millennium, with a collective burden equivalent to HIV/AIDS, tuberculosis, or malaria. A global response was therefore warranted.
MAIN TEXT
The World Health Organization (WHO) conceived an innovative strategy in the early 2000s to combat NTDs as a group of diseases, based on a combination of five public health interventions. Access to essential NTD medicines has hugely improved thanks to strong public-private partnership involving the pharmaceutical sector. The combination of a WHO NTD roadmap with clear targets to be achieved by 2020 and game-changing partner commitments endorsed in the London Declaration on Neglected Tropical Diseases, have led to unprecedented progress in the implementation of large-scale preventive treatment, case management and care of NTDs. The coming decade will see as challenges the mainstreaming of these NTD interventions into Universal Health Coverage and the coordination with other sectors to get to the roots of poverty and scale up transmission-breaking interventions. Chinese expertise with the elimination of multiple NTDs, together with poverty reduction and intersectoral action piloted by municipalities and local governments, can serve as a model for the latter. The international community will also need to keep a specific focus on NTDs in order to further steer this global response, manage the scaling up and sustainment of NTD interventions globally, and develop novel products and implementation strategies for NTDs that are still lagging behind.
CONCLUSIONS
The year 2020 will be crucial for the future of the global response to NTDs. Progress against the 2020 roadmap targets will be assessed, a new 2021-2030 NTD roadmap will be launched, and the London Declaration commitments will need to be renewed. It is hoped that during the coming decade the global response will be able to further build on today's successes, align with the new global health and development frameworks, but also keep focused attention on NTDs and mobilize enough resources to see the effort effectively through to 2030.
Topics: Communicable Disease Control; Global Health; Humans; Neglected Diseases; Poverty; Tropical Medicine
PubMed: 31987053
DOI: 10.1186/s40249-020-0630-9 -
Annals of Global Health 2014
Topics: Chikungunya Fever; Dengue; Developing Countries; Global Health; Hemorrhagic Fever, Ebola; Humans; Neglected Diseases; Tropical Medicine; Tuberculosis, Multidrug-Resistant
PubMed: 25960090
DOI: 10.1016/j.aogh.2015.02.1040 -
Systematic Reviews Aug 2023More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most... (Review)
Review
BACKGROUND
More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most vulnerable, and hard to reach geographical areas. The NTDs cause significant social and economic burden and deepen marginalization and stigmatization. The World Health Organization's current roadmap for NTD aims to prevent, control, eliminate, or eradicate 20 tropical diseases. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine, and/or care has been little explored to inform the country's NTD strategic plan. The overall purpose of the scoping review was to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine, and/or care in Ethiopia.
METHODS
A systematic search of evidence was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022, without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review was followed for screening of studies. Key findings were extracted and narrated qualitatively.
RESULTS
The search resulted in 4532 articles, of which 105 met the inclusion criteria and were included in the scoping review under three themes: burden of NTDs, access to diagnostics, medicine and/or care, and key barriers. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high, and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country.
CONCLUSIONS
The scoping review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment, and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies.
Topics: Humans; Ethiopia; Quality of Life; Tropical Medicine; Global Health; Neglected Diseases; Health Services Accessibility
PubMed: 37580784
DOI: 10.1186/s13643-023-02302-5 -
The Lancet. Microbe Jan 2024
Topics: Tropical Medicine; Societies, Medical
PubMed: 38147881
DOI: 10.1016/S2666-5247(23)00400-7 -
Medecine Et Sante Tropicales Feb 2019
Topics: Humans; Neglected Diseases; Tropical Medicine
PubMed: 31031249
DOI: 10.1684/mst.2019.0867 -
Tropical Medicine & International... Jan 2019
Topics: Global Health; Humans; International Cooperation; Tropical Medicine
PubMed: 30618156
DOI: 10.1111/tmi.13091 -
Tropical Medicine & International... Jul 2018
Topics: Global Health; Humans; Tropical Medicine
PubMed: 29969846
DOI: 10.1111/tmi.12953 -
Tropical Medicine & International... Jun 2018
Topics: Global Health; Humans; Tropical Medicine
PubMed: 29864267
DOI: 10.1111/tmi.12951 -
Tropical Medicine & International... May 2018
Topics: Communicable Diseases, Emerging; Global Health; Humans; International Cooperation; Tropical Medicine
PubMed: 29717797
DOI: 10.1111/tmi.12949