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Revista Espanola de Quimioterapia :... Oct 2023
Topics: Child; Humans; Corynebacterium; Anti-Bacterial Agents; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Bacteremia
PubMed: 37462015
DOI: 10.37201/req/126.2022 -
Revista Espanola de Quimioterapia :... Aug 2021
Topics: Corynebacterium; Exudates and Transudates; Humans; Otitis Media
PubMed: 34081421
DOI: 10.37201/req/011.2021 -
Frontiers in Cellular and Infection... 2020and are common bacteria of the human ear. They have frequently been isolated from the middle ear of children with otitis media (OM), though their potential role in... (Review)
Review
and are common bacteria of the human ear. They have frequently been isolated from the middle ear of children with otitis media (OM), though their potential role in this disease remains unclear and confounded due to their presence as commensal inhabitants of the external auditory canal. In this review, we summarize the current literature on these organisms with an emphasis on their role in OM. Much of the literature focuses on the presence and abundance of these organisms, and little work has been done to explore their activity in the middle ear. We find there is currently insufficient evidence available to determine whether these organisms are pathogens, commensals or contribute indirectly to the pathogenesis of OM. However, building on the knowledge currently available, we suggest future approaches aimed at providing stronger evidence to determine whether and are involved in the pathogenesis of OM. Such evidence will increase our understanding of the microbial risk factors contributing to OM and may lead to novel treatment approaches for severe and recurrent disease.
Topics: Bacteria; Carnobacteriaceae; Child; Corynebacterium; Humans; Otitis Media
PubMed: 32117817
DOI: 10.3389/fcimb.2020.00051 -
Revista Espanola de Quimioterapia :... Jun 2021
Topics: Corynebacterium; Humans; Otitis
PubMed: 33715319
DOI: 10.37201/req/144.2020 -
BMC Infectious Diseases Oct 2023Turicella otitidis belongs to the Corynebacteriaceae family and is a normal inhabitant of the ear and exists in a commensal relationship with its host. In children, T....
Turicella otitidis belongs to the Corynebacteriaceae family and is a normal inhabitant of the ear and exists in a commensal relationship with its host. In children, T. otitidis is frequently associated with otitis media. The emergence of Turicella otitidis as a pathogen is concerning, particularly due to the limited availability of data on its pathogenic properties. The objective of this study is to conduct a systematic review of T. otitidis infections occurring in both the ear and other anatomical sites, and to summarize the differences in metabolism and genome sequences between isolates obtained from the ear and blood.
Topics: Child; Humans; Virulence; Otitis Media; Corynebacterium; Actinomycetales
PubMed: 37891485
DOI: 10.1186/s12879-023-08721-y -
Revista Chilena de Infectologia :... Dec 2012
Topics: Corynebacterium
PubMed: 23412035
DOI: 10.4067/S0716-10182012000700011 -
The Pediatric Infectious Disease Journal Dec 2002The recently described coryneform bacteria and were first detected in the middle ear of patients with acute otitis media and chronic otitis media. Whether these bacteria... (Comparative Study)
Comparative Study
BACKGROUND
The recently described coryneform bacteria and were first detected in the middle ear of patients with acute otitis media and chronic otitis media. Whether these bacteria play an essential role in the pathogenesis of otitis media with effusion (OME) is unclear.
METHODS
In a prospective study 60 children with OME and 205 controls were evaluated to determine the incidence of and. Swabs from the external auditory canal (EAC) and the middle ear effusion (MEE) of OME children undergoing tympanotomy, ventilation tube insertion or both were cultured. Swabs from the EAC from healthy children served as controls.
RESULTS
In control children was found in EAC swabs from 23 of 205 (11.2%) and in 32 of 205 (15.6%). was isolated from 14 of 60 (23.3%) OME patients from the EAC only and in 6 of 60 (10.0%) OME patients from both EAC and MEE. was isolated in 2 of 60 (3.3%) from the EAC only and in 1 of 60 (1.7%) from both EAC and MEE. In no patient did or grow exclusively from MEE.
CONCLUSION
and may be part of the normal bacterial flora of the EAC in some children. Neither organism seems to cause OME in children.
Topics: Age Distribution; Anti-Bacterial Agents; Case-Control Studies; Child; Child, Preschool; Combined Modality Therapy; Corynebacterium; Corynebacterium Infections; Drug Resistance, Microbial; Female; Follow-Up Studies; Humans; Incidence; Infant; Male; Microbial Sensitivity Tests; Middle Ear Ventilation; Otitis Media with Effusion; Probability; Prospective Studies; Reference Values; Risk Assessment; Sensitivity and Specificity; Sex Distribution
PubMed: 12488661
DOI: 10.1097/00006454-200212000-00007 -
Future Microbiology Sep 2016While formerly known infections of Corynebacterium ulcerans are rare and mainly associated with contact to infected cattle, C. ulcerans has become an emerging pathogen... (Review)
Review
While formerly known infections of Corynebacterium ulcerans are rare and mainly associated with contact to infected cattle, C. ulcerans has become an emerging pathogen today. In Western Europe, cases of respiratory diphtheria caused by C. ulcerans have been reported more often than infections by Corynebacterium diphtheria, while systemic infections are also increasingly reported. Little is known about factors that contribute to host colonization and virulence of this zoonotic pathogen. Research in this field has received new impetus by the publication of several C. ulcerans genome sequences in the past years. This review gives a comprehensive overview of the basic knowledge of C. ulcerans, as well as the recent advances made in the analysis of putative virulence factors.
Topics: Animals; Bacterial Proteins; Cattle; Cattle Diseases; Corynebacterium; Corynebacterium Infections; Humans; Virulence; Virulence Factors
PubMed: 27545005
DOI: 10.2217/fmb-2016-0085 -
Enfermedades Infecciosas Y... Feb 1990
Topics: Corynebacterium; Corynebacterium Infections; Drug Resistance, Microbial; Humans
PubMed: 2098141
DOI: No ID Found -
Journal of Medical Microbiology Oct 2019In Western Europe, the incidence of both respiratory and cutaneous diphtheria, caused by toxin-producing , or , has been low over the past few decades thanks to the use...
In Western Europe, the incidence of both respiratory and cutaneous diphtheria, caused by toxin-producing , or , has been low over the past few decades thanks to the use of an effective vaccine and a high level of vaccination coverage. However, the disease has still not been eradicated and continues to occur in all of Europe. In order to prevent sequelae or a fatal outcome, diphtheria antitoxin (DAT) should be administered to suspected diphtheria patients as soon as possible, but economic factors and issues concerning regulations have led to poor availability of DAT in many countries. The European Centre for Disease Prevention and Control and World Health Organization have called for European Union-wide solutions to this DAT-shortage. In order to illustrate the importance of these efforts and underline the need for continued diphtheria surveillance, we present data on all registered cases of toxigenic and non-toxigenic , and in Belgium during the past decade, up to and including 2017.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Belgium; Child, Preschool; Corynebacterium; Diphtheria; Diphtheria Toxin; Drug Resistance, Bacterial; Female; Humans; Male; Middle Aged
PubMed: 31418673
DOI: 10.1099/jmm.0.001039