Antibiotic
cefotetan
Brand Names:
Cefotan
Effect:
Decreased Cell Wall Synthesis & Repair
May Prevent:
Pregnancy Complications, Infectious; Surgical Wound Infection
May Treat:
Abscess;
Bacteroides Infections;
Bites, Human;
Bone Diseases, Infectious;
Clostridium Infections;
Escherichia coli Infections;
Fusobacterium Infections;
Gonorrhea;
Haemophilus Infections;
Klebsiella Infections;
Peritonitis;
Pregnancy Complications, Infectious;
Proteus Infections;
Respiratory Tract Infections;
Sepsis;
Skin Diseases, Bacterial;
Soft Tissue Infections;
Staphylococcal Infections;
Streptococcal Infections;
Surgical Wound Infection;
Urinary Tract Infections
More Information:
Definitions related to cefotetan:
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A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A semi-synthetic, broad-spectrum, beta-lactamase-resistant, second-generation cephalosporin antibiotic derived from cephalosporium. The bactericidal activity of cefotetan disodium is caused by an inhibition of bacterial cell wall synthesis via inhibition of cross-linking of peptidoglycans. This results in a reduction of cell wall stability and causes cell lysis. Cefotetan disodium is more active against gram-negative organisms and less active against gram-positive organisms compared to first-generation cephalosporins.NCI ThesaurusU.S. National Cancer Institute, 2021
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