Antibiotic
clarithromycin Audio
[ kluh-rith-roh-my-sin ]
Brand Names:
Biaxin
Effect:
Decreased Protein Synthesis
May Prevent:
Endocarditis, Bacterial; Mycobacterium Infections, Nontuberculous
May Treat:
Bronchitis; Chlamydia Infections; Duodenal Ulcer; Haemophilus Infections; Helicobacter Infections; Mycobacterium Infections, Nontuberculous; Otitis Media; Pneumonia, Mycoplasma; Sinusitis; Skin Diseases, Infectious; Staphylococcal Infections; Streptococcal Infections; Tonsillitis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to clarithromycin:
  • A semisynthetic 14-membered ring macrolide antibiotic. Clarithromycin binds to the 50S ribosomal subunit and inhibits RNA-dependent protein synthesis in susceptible organisms. Clarithromycin has been shown to eradicate gastric MALT (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic Helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An antibiotic drug used to treat infection. It belongs to the family of drugs called macrolides.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Semi-synthetic macrolide antibiotic; derivative of erythromycin.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.