Antibiotic
roxithromycin
Effect:
Decreased Protein Synthesis
May Prevent:
Bacterial Infections
May Treat:
Gram-Negative Bacterial Infections; Legionnaires' Disease
Definitions related to roxithromycin:
  • A semi-synthetic derivative of the macrolide antibiotic erythromycin that includes an N-oxime side chain on the lactone ring, with antibacterial and anti-malarial activities. Roxithromycin binds to the subunit 50S of the bacterial ribosome, which inhibits bacterial protein synthesis and leads to inhibition of bacterial cell growth and replication.
    NCI
    U.S. National Cancer Institute, 2021
  • Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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