Pharmacologic Substance
cyclooxygenase inhibitor Audio
[ sy-kloh-ok-sih-jeh-nays in-hih-bih-ter ]
Subclass of:
Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors
Definitions related to cyclooxygenase inhibitors:
  • A type of drug that is used to treat inflammation and pain, and is being studied in the prevention and treatment of cancer. COX inhibitors belong to the family of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • Any agent that inhibits prostaglandin G/H synthase (cyclooxygenase or COX), an enzyme that catalyzes the production of prostanoids, including prostaglandins, prostacyclin and thromboxane, from arachidonic acid. Cyclooxygenase inhibitors are a type of non-steroidal anti-inflammatory drug.
    NCI
    U.S. National Cancer Institute, 2021
  • Compounds or agents that combine with cyclooxygenase (PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES) and thereby prevent its substrate-enzyme combination with arachidonic acid and the formation of eicosanoids, prostaglandins, and thromboxanes.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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