Pharmacologic Substance
phosphodiesterase inhibitor
Subclass of:
Enzyme Inhibitors
Definitions related to phosphodiesterase inhibitors:
  • Any substance or agent which suppresses, prevents or opposes the actions or biosynthesis of phosphodiesterases.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Any substance that inhibits phosphodiesterase, an enzyme that catalyzes the breaking of a phosphodiester bond. Usually, this refers to cyclic nucleotide phosphodiesterase, an enzyme that breaks the phosphodiester bond in the second messenger molecules cAMP and cGMP. Inhibition of cyclic nucleotide phosphodiesterase can be used to affect vasodilation.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.