Pharmacologic Substance
dipyridamole Audio
di·pyr·id·a·mole [ dahy-pir-i-duh-mohl, -puh-rid-uh- ]
Brand Names:
Aggrenox
Effect:
Coronary Arterial Vasodilation
May Prevent:
Coronary Thrombosis; Graft Occlusion, Vascular
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to dipyridamole:
  • A drug that prevents blood cell clumping and enhances the effectiveness of fluorouracil and other chemotherapeutic agents.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic agent derivative of pyrimido-pyrimidine, with antiplatelet properties. Dipyridamole inhibits adenosine uptake by platelets and endothelial cells, triggering an accumulation of cyclic adenosine monophosphate (cAMP), and inhibiting the stimulation of platelet aggregation by agents such as platelet activating factor and collagen. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • Platelet inhibitor and coronary vasodilator used to prevent thromboembolism associated with mechanical heart valves, as prophylactic adjunct in the prevention of myocardial reinfarction, and as a diagnostic aid adjunct in myocardial perfusion imaging; administered orally and intravenously.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.