Pharmacologic Substance
mopidamol
Subclass of:
Pyrimidines
Definitions related to mopidamol:
  • A derivative of dipyridamole that is a phosphodiesterase inhibitor, with potential antiplatelet activity. Mopidamol inhibits the hydrolysis of cyclic nucleotides, such as cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP), by cyclic nucleotide phosphodiesterases; thus, cAMP- and cGMP-dependent processes are potentiated. This leads to the induction of prostacyclin synthesis, the inhibition of thromboxane B2 synthesis and prevention of platelet activation and aggregation.
    NCI
    U.S. National Cancer Institute, 2021
  • A phosphodiesterase inhibitor which inhibits platelet aggregation. Formerly used as an antineoplastic.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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