Neoplastic Process
leiomyosarcoma

[ ly-oh-my-oh-sar-koh-muh ]
Subclass of:
Neoplasms, Muscle Tissue;
Sarcoma
Definitions related to leiomyosarcoma:
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(leiomyosarcoma, malignant) A malignant neoplasm, originating from smooth muscle cells.CDISC TerminologyClinical Data Interchange Standards Consortium (CDISC), 2021
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A malignant (cancer) tumor of smooth muscle cells that can arise almost anywhere in the body, but is most common in the uterus, abdomen, or pelvis.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A malignant tumor of smooth muscle cells that can arise almost anywhere in the body but is most common in the uterus, abdomen, or pelvis.U.S. FDA GlossaryU.S. Food & Drug Administration, 2021
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A rare soft tissue sarcoma characterized by a malignant space-occupying lesion most commonly located in the retroperitoneum or the inferior vena cava, but also other soft tissues, and composed of cells showing distinct features of smooth muscle cells. The tumor presents with mass effect depending on the location. It is capable of both local recurrence and distant metastasis, while lymph node metastasis is rare. Prognosis largely depends on tumor location and size.OrphaNetINSERM, 2021
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A sarcoma containing large spindle cells of smooth muscle. Although it rarely occurs in soft tissue, it is common in the viscera. It is the most common soft tissue sarcoma of the gastrointestinal tract and uterus. The median age of patients is 60 years. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p1865)NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A smooth muscle connective tissue tumor, which is rare type of cancer that is a malignant neoplasm of smooth muscle. When such a neoplasm is benign, it is called a leiomyoma.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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An uncommon, aggressive malignant smooth muscle neoplasm, usually occurring in post-menopausal women. It is characterized by a proliferation of neoplastic spindle cells. Morphologic variants include epithelioid, granular cell, inflammatory and myxoid leimyosarcomas.NCI ThesaurusU.S. National Cancer Institute, 2021
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Sarcoma containing large spindle cells of smooth muscle; although it rarely occurs in soft tissue, it is common in the viscera; the most common soft tissue sarcoma of the uterus and retroperitoneal region.CRISP ThesaurusNational Institutes of Health, 2006
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Leiomyosarcoma is a rare type of cancer that affects smooth muscle tissue. These tumors are most common in the abdomen, but can occur anywhere in the body, including the uterus. Other common sites include blood vessels and skin.Mayo Foundation for Medical Education and Research
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Leiomyosarcoma is a rare cancerous tumor that consists of smooth (involuntary) muscle cells. Leiomyosarcoma is a type of sarcoma. It spreads through the blood stream and can affect the lungs, liver, blood vessels, or any other soft tissue in the body. The exact cause of leiomyosarcoma is not known, although genetic and environmental...National Center for Advancing Translational Sciences
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