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adenosarcoma
carcinosarcoma
chondrosarcoma
phyllodes tumor
fibrosarcoma
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leiomyosarcoma
lipoma
lymphangiosarcoma
Neoplastic Process
liposarcoma Audio
[ lih-poh-sar-koh-muh ]
Subclass of:
Lipomatous neoplasm; Sarcoma
Definitions related to liposarcoma:
  • (liposarcoma, malignant) A malignant neoplasm composed of adipose tissue.
    CDISC Terminology
    Clinical Data Interchange Standards Consortium (CDISC), 2021
  • A malignant tumor derived from primitive or embryonal lipoblastic cells. It may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid (LIPOSARCOMA, MYXOID), round-celled, or pleomorphic, usually in association with a rich network of capillaries. Recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces. (From Dorland, 27th ed; Stedman, 25th ed)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A usually painless malignant tumor that arises from adipose tissue. Microscopically, it may contain a spectrum of neoplastic adipocytes ranging from lipoblasts to pleomorphic malignant adipocytes. Morphologic variants include: well differentiated, dedifferentiated, pleomorphic, and myxoid liposarcoma. The metastatic potential is higher in less differentiated tumors.
    NCI
    U.S. National Cancer Institute, 2021
  • Liposarcoma (LS), a type of soft tissue sarcoma, describes a group of lipomatous tumors of varying severity ranging from slow-growing to aggressive and metastatic. Liposarcomas are most often located in the lower extremities or retroperitoneum, but they can also occur in the upper extremities, neck, peritoneal cavity, spermatic cord, breast, vulva and axilla.
    OrphaNet
    INSERM, 2021
  • Malignant neoplasms which probably originate in primitive mesenchymal stem cell populations differentiating down a lipomatous pathway.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Malignant tumor derived from primitive or embryonal lipoblastic cells; may be composed of well-differentiated fat cells or may be dedifferentiated: myxoid, round-celled, or pleomorphic, usually in association with a rich network of capillaries; recurrences are common and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Liposarcoma is a malignancy of fat cells (see Liposarcoma in the Pediatric Medicine section and Liposarcoma, Soft Tissue in the Radiology section). In adults, it is the most common soft tissue sarcoma.
    Medscape
    WebMD, 2025
  • Liposarcoma is a rare type of cancer that begins in the fat cells. Liposarcoma is considered a type of soft tissue sarcoma.
    Mayo Clinic
    Mayo Foundation for Medical Education and Research, 2025
  • Liposarcoma is a tumor that arises from fat tissue. This tumor often occurs in the thigh, legs, behind the knee, or in the abdomen, but it can be found in other parts of the body, in the retroperitoneum; and, less often, in the head and neck area. Their primary occurrence in the skin is rare. Because a liposarcoma may grow into...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.

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