Congenital Abnormality
macrocephaly
mac·ro·ceph·a·ly
Subclass of:
Malformations of Cortical Development, Group I;
Craniofacial Abnormalities
Definitions related to macrocephaly:
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An abnormal increase in head circumference, which can have a variety of causes, including hydrocephalus, enlarged brain, and cranial hyperostosis.NCI ThesaurusU.S. National Cancer Institute, 2021
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(megalencephaly) A congenital abnormality in which the occipitofrontal circumference is greater than two standard deviations above the mean for a given age. It is associated with HYDROCEPHALUS; SUBDURAL EFFUSION; ARACHNOID CYSTS; or is part of a genetic condition (e.g., ALEXANDER DISEASE; SOTOS SYNDROME).NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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(megalencephaly) Diffuse enlargement of the entire cerebral hemispheres leading to macrocephaly (with or without overlying cortical dysplasia).Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Macrocephaly (megacephaly) is a head circumference > 2 standard deviations above the mean for age (1, 2).Merck & Co., Inc., 2020
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